Sign In


Kalpana Ghoshal PhD

Kalpana Ghoshal PhD
Assoc ProfessorCollege of MedicineKalpana.Ghoshal@osumc.edu
646C Tzagournis Med Res Fac 420 W 12th Avenue Columbus OH 43210
Phone:614-292-8865Fax: 614-292-4118
  • Experimental Therapeutics

Current Publications

  • He S, Chu J, Wu LC, Mao H, Peng Y, Alvarez-Breckenridge CA, Hughes T, Wei M, Zhang J, Yuan S, Sandhu S, Vasu S, Benson DM Jr, Hofmeister C, He X, Ghoshal K, Devine SM, Caligiuri MA, Yu JMicroRNAs activate natural killer cells through toll-like receptor signaling.Blood in press 4/11/2013
  • Zhang M, Zhou X, Wang B, Yung BC, Lee LJ, Ghoshal K, Lee RJLactosylated gramicidin-based lipid nanoparticles (Lac-GLN) for targeted delivery of anti-miR-155 to hepatocellular carcinoma.J Control Release in press 4/6/2013
  • Hsu SH, Motiwala T, Roy S, Claus R, Mustafa M, Plass C, Freitas MA, Ghoshal K, Jacob STMethylation of gene encoding the growth suppressor protein tyrosine phosphatase receptor-type O (PTPRO) in human hepatocellular carcinoma and identification of VCP as its bona fide substrate.J Cell Biochem in press 3/26/2013
  • Hsu SH, Ghoshal KMicroRNAs in Liver Health and Disease.Curr Pathobiol Rep 1(1) 53-62 3/1/2013
  • Yu B, Hsu SH, Zhou C, Wang X, Terp MC, Wu Y, Teng L, Mao Y, Wang F, Xue W, Jacob ST, Ghoshal K, Lee RJ, Lee LJLipid nanoparticles for hepatic delivery of small interfering RNA.Biomaterials 33(25) 5924-34 9/1/2012
  • Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, Jacob ST, Mendell JT, Ghoshal KEssential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver.J Clin Invest 122(8) 2871-83 8/1/2012
  • Wang B, Hsu S, Frankel W, Ghoshal K, Jacob STStat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.Hepatology 56(1) 186-97 7/1/2012
  • Kutay H, Klepper C, Wang B, Hsu SH, Datta J, Yu L, Zhang X, Majumder S, Motiwala T, Khan N, Belury M, McClain C, Jacob S, Ghoshal KReduced susceptibility of DNA methyltransferase 1 hypomorphic (Dnmt1N/+) mice to hepatic steatosis upon feeding liquid alcohol diet.PLoS One 7(8) e41949 1/1/2012
  • Datta J, Ghoshal K, Motiwala T, Jacob STNovel Insights into the Molecular Mechanism of Action of DNA Hypomethylating Agents: Role of Protein Kinase C δ in Decitabine-Induced Degradation of DNA Methyltransferase 1.Genes Cancer 3(1) 71-81 1/1/2012