Said Sif MSc, PhD

Said Sif MSc, PhD
Assoc ProfessorCollege of Medicinesif.1@osu.edu
468 Hamilton Hall 1645 Neil Avenue Columbus Ohio 43210
Phone:614-247-7445Alternate Phone:624-688-5494Fax: 614-292-4118
  • Experimental Therapeutics

Current Publications

  • Baiocchi RAGenetic Validation of the Protein Arginine Methyltransferase PRMT5 as a Candidate Therapeutic Target in Glioblastoma.Cancer Res 74 1752-65 3/15/2014
  • Bronisz A, Carey HA, Godlewski J, Sif S, Ostrowski MC, Sharma SMThe Multifunctional Protein Fused in Sarcoma (FUS) Is a Coactivator of Microphthalmia-associated Transcription Factor (MITF).J Biol Chem 289 326-34 1/3/2014
  • Otterson GACellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors.Diagn Pathol 8 201 12/10/2013
  • Chung J, Karkhanis V, Tae S, Yan F, Smith P, Ayers LW, Agostinelli C, Pileri S, Denis GV, Baiocchi RA, Sif SProtein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.J Biol Chem 288 35534-47 12/6/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu