Theodoros Teknos N MD

Theodoros Teknos N MD
ProfessorCollege of
B-222 Starling Loving Hall 320 W 10th Avenue Columbus Ohio 43210
  • Translational Therapeutics

Research Description

Dr. Teknos' research interests include: Cancer stem cell biology, cancer cell signalling, predictors of metastasis, predictors of treatment response, tumor/metastasis prevention.

Current Publications

  • Shen TK, Teknos TN, Toland AE, Senter L, Nagy RSalivary Gland Cancer in BRCA-Positive Families : A Retrospective Review.JAMA Otolaryngol Head Neck Surg in press 9/25/2014
  • Durmus K, Patwa HS, Gokozan HN, Kucur C, Teknos TN, Agrawal A, Old MO, Ozer EFunctional and quality-of-life outcomes of transoral robotic surgery for carcinoma of unknown primary.Laryngoscope 124 2089-95 9/1/2014
  • Kucur C, Durmus K, Teknos TN, Ozer EHow often parapharyngeal space is encountered in TORS oropharynx cancer resection.Eur Arch Otorhinolaryngol in press 8/21/2014
  • Xie X, Teknos TN, Pan QAre All Cancer Stem Cells Created Equal?Stem Cells Transl Med in press 8/13/2014
  • Durmus K, Rangarajan SV, Old MO, Agrawal A, Teknos TN, Ozer ETransoral robotic approach to carcinoma of unknown primary.Head Neck 36 848-52 6/1/2014
  • Calli C, Teknos TN, Agrawal A, Schuller DE, Ozer E, Songu MDoes body mass index matter while selecting the flap type for pharyngeal reconstructions?J Craniofac Surg 25 780-2 5/1/2014
  • Islam M, Datta J, Lang JC, Teknos TNDown regulation of RhoC by microRNA-138 results in de-activation of FAK, Src and Erk1/2 signaling pathway in head and neck squamous cell carcinoma.Oral Oncol 50 448-56 5/1/2014
  • Byrd S, Maxwell JH, Urba S, Bradford CR, Carey TE, Worden FP, Dobrosotskaya IY, Bellile E, Spector ME, Kumar B, Feng F, Eisbruch A, Wolf GT, Prince ME, Moyer JS, Teknos T, Chepeha DB, Walline HM, McHugh JB, Cordell KG, Ward PDWeekly chemotherapy with radiation versus high-dose cisplatin with radiation as organ preservation for patients with HPV-positive and HPV-negative locally advanced squamous cell carcinoma of the oropharynx.Head Neck 36 617-23 5/1/2014
  • Xie X, Piao L, Cavey GS, Old M, Teknos TN, Mapp AK, Pan QPhosphorylation of Nanog is essential to regulate Bmi1 and promote tumorigenesis.Oncogene 33 2040-52 4/17/2014
  • Arshad H, Ozer HG, Thatcher A, Old M, Ozer E, Agarwal A, Jafari H, Birkheimer D, Basinger H, Forest LA, Schuller DE, Teknos TNIntensive care unit versus non-intensive care unit postoperative management of head and neck free flaps: comparative effectiveness and cost comparisons.Head Neck 36 536-9 4/1/2014
  • Agrawal A, Ozer E, Schuller DE, Teknos TN, Pan Q, Zhang M, Kumar B, Piao L, Xie X, Schmitt A, Arradaza N, Cippola M, Old MElevated intrinsic cancer stem cell population in human papillomavirus-associated head and neck squamous cell carcinoma.Cancer 120 992-1001 4/1/2014
  • Xie X, Piao L, Bullock BN, Smith A, Su T, Zhang M, Teknos TN, Arora PS, Pan QTargeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma.Oncogene 33 1037-46 2/20/2014
  • Chinn SB, Spector ME, Bellile EL, Rozek LS, Lin T, Teknos TN, Prince ME, Bradford CR, Urba SG, Carey TE, Eisbruch A, Wolf GT, Worden FP, Chepeha DBEfficacy of induction selection chemotherapy vs primary surgery for patients with advanced oral cavity carcinoma.JAMA Otolaryngol Head Neck Surg 140 134-42 2/1/2014
  • Akagi K, Li J, Broutian TR, Padilla-Nash H, Xiao W, Jiang B, Rocco JW, Teknos TN, Kumar B, Wangsa D, He D, Ried T, Symer DE, Gillison MLGenome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability.Genome Res 24 185-99 2/1/2014
  • Islam M, Sharma S, Teknos TNRhoC regulates cancer stem cells in head and neck squamous cell carcinoma by overexpressing IL-6 and phosphorylation of STAT3.PLoS One 9 e88527 1/1/2014
  • Kumar B, Yadav A, Hideg K, Kuppusamy P, Teknos TN, Kumar PA novel curcumin analog (H-4073) enhances the therapeutic efficacy of cisplatin treatment in head and neck cancer.PLoS One 9 e93208 1/1/2014
  • Bradford CR, Kumar B, Bellile E, Lee J, Taylor J, D'Silva N, Cordell K, Kleer C, Kupfer R, Kumar P, Urba S, Worden F, Eisbruch A, Wolf GT, Teknos TN, Prince ME, Chepeha DB, Hogikyan ND, Moyer JS, Carey TEBiomarkers in advanced larynx cancer.Laryngoscope 124 179-87 1/1/2014
  • Santaliz-Ruiz LE, Xie X, Old M, Teknos TN, Pan Q, James AG, Solove RJEmerging role of nanog in tumorigenesis and cancer stem cells.Int J Cancer in press 12/21/2013
  • Dziegielewski PT, Teknos TN, Durmus K, Old M, Agrawal A, Kakarala K, Marcinow A, Ozer ETransoral robotic surgery for oropharyngeal cancer: long-term quality of life and functional outcomes.JAMA Otolaryngol Head Neck Surg 139 1099-108 11/1/2013
  • Marcinow A, Ozer E, Teknos T, Wei L, Hurtuk A, Old M, Agrawal A, Carrau R, Iwenofu OHClinicopathologic predictors of recurrence and overall survival in adenoid cystic carcinoma of the head and neck: A single institutional experience at a tertiary care center.Head Neck in press 10/25/2013
  • Marcinow AM, Hall N, Byrum E, Teknos TN, Old MO, Agrawal AUse of a novel receptor-targeted (CD206) radiotracer, 99mTc-tilmanocept, and SPECT/CT for sentinel lymph node detection in oral cavity squamous cell carcinoma: initial institutional report in an ongoing phase 3 study.JAMA Otolaryngol Head Neck Surg 139 895-902 9/1/2013
  • Kaka AS, Kumar B, Kumar P, Wakely PE Jr, Kirsch CM, Old MO, Ozer E, Agrawal A, Carrau RE, Schuller DE, Siddiqui F, Teknos TNHighly aggressive human papillomavirus-related oropharyngeal cancer: clinical, radiologic, and pathologic characteristics.Oral Surg Oral Med Oral Pathol Oral Radiol 116 327-35 9/1/2013
  • Tassone P, Old M, Teknos TN, Pan Qp53-based therapeutics for head and neck squamous cell carcinoma.Oral Oncol 49 733-7 8/1/2013
  • Durmus K, Kakarala K, Old MO, Teknos TN, Ozer EAnterolateral thigh butterfly free flap reconstruction for peristomal recurrence following laryngectomy: our experience in six patients.Clin Otolaryngol 38 339-42 8/1/2013
  • Islam M, Sharma S, Kumar B, Teknos TNAtorvastatin inhibits RhoC function and limits head and neck cancer metastasis.Oral Oncol 49 778-86 8/1/2013
  • Ozer E, Alvarez B, Kakarala K, Durmus K, Teknos TN, Carrau RLClinical outcomes of transoral robotic supraglottic laryngectomy.Head Neck 35 1158-61 8/1/2013
  • Zhang M, Taylor CE, Piao L, Datta J, Bruno PA, Bhave S, Su T, Lang JC, Xie X, Teknos TN, Mapp AK, Pan QGenetic and chemical targeting of epithelial-restricted with serine box reduces EGF receptor and potentiates the efficacy of afatinib.Mol Cancer Ther 12 1515-25 8/1/2013
  • Smith A, Teknos TN, Pan QEpithelial to mesenchymal transition in head and neck squamous cell carcinoma.Oral Oncol 49 287-92 4/1/2013
  • McClurg SW, Leon M, Teknos TN, Iwenofu OHChondromyxoid fibroma of the nasal septum: case report and review of literature.Head Neck 35 E1-5 1/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 460 W. 10th Avenue, Columbus, OH 43210 Phone: 1-800-293-5066 | Email: