Quintin Pan PhD

Quintin Pan PhD
Assoc ProfessorCollege of Medicinepan.116@osu.edu
442 Tzagournis Med Res Facility 420 W 12th Avenue Columbus Ohio 43210
Phone:614-247-4438Fax:
  • Translational Therapeutics

Research Description

Dr. Pan’s research is focused on understanding the genetic determinants of aggressive head and neck cancer. His laboratory is interested in identifying "druggable" genes/targets, to understand how these genes function in the context of head and neck cancer development and progression, and to design selective inhibitors against these genes as novel anti-cancer therapeutics

Current Publications

  • Xie X, Teknos TN, Pan QAre All Cancer Stem Cells Created Equal?Stem Cells Transl Med in press 8/13/2014
  • Xie X, Piao L, Cavey GS, Old M, Teknos TN, Mapp AK, Pan QPhosphorylation of Nanog is essential to regulate Bmi1 and promote tumorigenesis.Oncogene 33 2040-52 4/17/2014
  • Kumar B, Piao L, Xie X, Schmitt A, Arradaza N, Cippola M, Old M, Agrawal A, Ozer E, Schuller DE, Teknos TN, Pan Q, Zhang MElevated intrinsic cancer stem cell population in human papillomavirus-associated head and neck squamous cell carcinoma.Cancer 120 992-1001 4/1/2014
  • Xie X, Piao L, Bullock BN, Smith A, Su T, Zhang M, Teknos TN, Arora PS, Pan QTargeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma.Oncogene 33 1037-46 2/20/2014
  • Santaliz-Ruiz LE, Xie X, Old M, Teknos TN, Pan Q, James AG, Solove RJEmerging role of nanog in tumorigenesis and cancer stem cells.Int J Cancer in press 12/21/2013
  • Tassone P, Old M, Teknos TN, Pan Qp53-based therapeutics for head and neck squamous cell carcinoma.Oral Oncol 49 733-7 8/1/2013
  • Zhang M, Taylor CE, Piao L, Datta J, Bruno PA, Bhave S, Su T, Lang JC, Xie X, Teknos TN, Mapp AK, Pan QGenetic and chemical targeting of epithelial-restricted with serine box reduces EGF receptor and potentiates the efficacy of afatinib.Mol Cancer Ther 12 1515-25 8/1/2013
  • Smith A, Teknos TN, Pan QEpithelial to mesenchymal transition in head and neck squamous cell carcinoma.Oral Oncol 49 287-92 4/1/2013
  • Datta J, Smith A, Lang JC, Islam M, Dutt D, Teknos TN, Pan QmicroRNA-107 functions as a candidate tumor-suppressor gene in head and neck squamous cell carcinoma by downregulation of protein kinase Cɛ.Oncogene 31 4045-53 9/6/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu