John J Lannutti PhD

ProfessorCollege of Engineeringlannutti.1@osu.eduwebsite

477 Watts Hall 2041 College Road Columbus OH 43210

Phone:614-292-3926Fax: 614-292-1537

Experimental Therapeutics

General Research Interest

application of aligned and random nanofibers as model substrates for the evaluation of tumor cell behavior in vitro. Development and application of new and existing chemotherapies on both cancer cell lines and human tumor explants in vitro. Modification of nanofiber chemistry and topography to improve in vitro relevance of these substrates to the tumor microenvironment.

Current Publications

Rao SS, Nelson MT, Xue R, Dejesus JK, Viapiano MS, Lannutti JJ, Sarkar A, Winter JOMimicking white matter tract topography using core-shell electrospun nanofibers to examine migration of malignant brain tumors.Biomaterials 34(21) 5181-90 7/1/2013
Agudelo-Garcia PA, De Jesus JK, Williams SP, Nowicki MO, Chiocca EA, Liyanarachchi S, Li PK, Lannutti JJ, Johnson JK, Lawler SE, Viapiano MSGlioma cell migration on three-dimensional nanofiber scaffolds is regulated by substrate topography and abolished by inhibition of STAT3 signaling.Neoplasia 13(9) 831-40 9/1/2011