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Jeffrey J Chalmers PhD

Jeffrey J Chalmers PhD
ProfessorCollege of Engineeringchalmers.1@osu.edu
333B Koffolt Laboratories 140 W 19th Avenue Columbus OH 43210
Phone:614-292-2727Fax: 614-292-3769
  • Experimental Therapeutics

General Research Interest

Bioengineering, Biochemical Engineering, Biomedical Engineering

Research Description

The research conducted in laboratories that I oversee involved the development of fundamental understanding and applications of the interaction of hydrodynamic and magnetic forces and cells.  This work can range from the development of fundamental mathematical relationship describing physical phenomena to the development of simple, robust instruments for use in a clinical setting. 

Transinstitutional Work

The Chalmers laboratory, in collaboration with Dr. Maciej Zborowski are developing magnetic cell separation instrumentation that is being used in collaboration with several clinical laboratories at the Cleveland Clinic and The James Cancer Hospital to detect circulating tumor cells in the blood of cancer patients.

Current Publications

  • Chen A, Byvank T, Chang WJ, Bharde A, Vieira G, Miller BL, Chalmers JJ, Bashir R, Sooryakumar ROn-chip magnetic separation and encapsulation of cells in droplets.Lab Chip 13(6) 1172-81 3/21/2013
  • Jin X, Chalmers JJ, Zborowski MIron transport in cancer cell culture suspensions measured by cell magnetophoresis.Anal Chem 84(10) 4520-6 5/15/2012
  • Lustberg M, Jatana KR, Zborowski M, Chalmers JJEmerging technologies for CTC detection based on depletion of normal cells.Recent Results Cancer Res 195 97-110 1/1/2012
  • Balasubramanian P, Lang JC, Jatana KR, Miller B, Ozer E, Old M, Schuller DE, Agrawal A, Teknos TN, Summers TA Jr, Lustberg MB, Zborowski M, Chalmers JJMultiparameter analysis, including EMT markers, on negatively enriched blood samples from patients with squamous cell carcinoma of the head and neck.PLoS One 7(7) e42048 1/1/2012
  • Garcia-Villa A, Balasubramanian P, Miller BL, Lustberg MB, Ramaswamy B, Chalmers JJAssessment of γ-H2AX levels in circulating tumor cells from patients receiving chemotherapy.Front Oncol 2 128 1/1/2012
  • Zborowski M, Chalmers JJRare cell separation and analysis by magnetic sorting.Anal Chem 83(21) 8050-6 11/1/2011