Tracey L. Papenfuss DVM, PhD, DACVP

Asst ProfessorCollege of Veterinary MedicineTracey.Papenfuss@osumc.edu

370 Vet Med Acad Bldg 1900 Coffey Road Columbus OH 43210

Phone:614-292-7343Fax: 614-292-6473

Innate Immunity

General Research Interest

Dr. Papenfuss is an immunologist with an interest in how the tumor microenvironment and endogenous steroid hormones alter immune cell function. Her laboratory investigates how antigen presenting cells (e.g. dendritic cells and macrophages) are altered by steroid hormones (e.g. sex hormones) and how this affects adaptive (T cell) immune responses. Dr. Papenfuss is also a board certified veterinary (experimental) pathologist that evaluates pathologic alterations in animal models of human disease including both cancer and inflammatory diseases.

Current Publications

Sherger M, Kisseberth W, London C, Olivo-Marston S, Papenfuss TLIdentification of myeloid derived suppressor cells in the peripheral blood of tumor bearing dogs.BMC Vet Res 8 209 10/31/2012
Wasserman J, Diese L, Vangundy Z, London C, Carson WE, Papenfuss TLSuppression of canine myeloid cells by soluble factors from cultured canine tumor cells.Vet Immunol Immunopathol 145(1-2) 420-30 1/15/2012
Park JK, Kogure T, Nuovo GJ, Jiang J, He L, Kim JH, Phelps MA, Papenfuss TL, Croce CM, Patel T, Schmittgen TDmiR-221 silencing blocks hepatocellular carcinoma and promotes survival.Cancer Res 71(24) 7608-16 12/15/2011