Xue-feng Bai MD, PhD

Xue-feng Bai MD, PhD
Assoc ProfessorCollege of Medicinebai.21@osu.edu
168 Hamilton Hall 1645 Neil Avenue Columbus Ohio 43210
Phone:614-292-8649Fax: (614) 292-7072
  • Translational Therapeutics

Research Description

Dr. Bai's laboratory studies the pathogenic mechanisms in immune-mediated diseases. They are particularly interested in T lymphocyte responses in autoimmune diseases and cancer. In autoimmune diseases such as multiple sclerosis, aberrant activation of T lymphocytes leads to their attack of the central nervous system (CNS).

Current Publications

  • Chu J, He S, Deng Y, Zhang J, Peng Y, Hughes T, Yi L, Kwon CH, Wang QE, Devine SM, He X, Bai XF, Hofmeister CC, Yu JGenetic modification of T cells redirected toward CS1 enhances eradication of myeloma cells.Clin Cancer Res 20 3989-4000 8/1/2014
  • Liao KL, Bai XF, Friedman AMathematical modeling of interleukin-27 induction of anti-tumor T cells response.PLoS One 9 e91844 1/1/2014
  • Liao KL, Bai XF, Friedman AMathematical modeling of interleukin-35 promoting tumor growth and angiogenesis.PLoS One 9 e110126 1/1/2014
  • Liao KL, Bai XF, Friedman AThe role of CD200-CD200R in tumor immune evasion.J Theor Biol 328 65-76 7/7/2013
  • Wang Z, Liu JQ, Liu Z, Shen R, Zhang G, Xu J, Basu S, Feng Y, Bai XFTumor-derived IL-35 promotes tumor growth by enhancing myeloid cell accumulation and angiogenesis.J Immunol 190 2415-23 3/1/2013
  • Liu Z, Yu J, Carson WE 3rd, Bai XFThe role of IL-27 in the induction of anti-tumor cytotoxic T lymphocyte response.Am J Transl Res 5 470-80 1/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 460 W. 10th Avenue, Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu