Tracey L Papenfuss DVM, PhD, DACVP

Tracey L Papenfuss DVM, PhD, DACVP
Asst ProfessorCollege of Veterinary Medpapenfuss.1@osu.edu
370 Veterinary Medicine Acad Bldg 1900 Coffey Road Columbus Ohio 43210
Phone:614-292-7343Fax: 614-292-6473
  • Non-Member

General Research Interest

Dr. Papenfuss is an immunologist with an interest in how the tumor microenvironment and endogenous steroid hormones alter immune cell function. Her laboratory investigates how antigen presenting cells (e.g. dendritic cells and macrophages) are altered by steroid hormones (e.g. sex hormones) and how this affects adaptive (T cell) immune responses. Dr. Papenfuss is also a board certified veterinary (experimental) pathologist that evaluates pathologic alterations in animal models of human disease including both cancer and inflammatory diseases.

Current Publications

  • Peine KJ, Guerau-de-Arellano M, Lee P, Kanthamneni N, Severin M, Probst GD, Peng H, Yang Y, Vangundy Z, Papenfuss TL, Lovett-Racke AE, Bachelder EM, Ainslie KMTreatment of Experimental Autoimmune Encephalomyelitis by Codelivery of Disease Associated Peptide and Dexamethasone in Acetalated Dextran Microparticles.Mol Pharm 11 828-835 3/3/2014
  • Peine KJ, Gupta G, Brackman DJ, Papenfuss TL, Ainslie KM, Satoskar AR, Bachelder EMLiposomal resiquimod for the treatment of Leishmania donovani infection.J Antimicrob Chemother 69 168-75 1/1/2014
  • Yasmeen R, Meyers JM, Alvarez CE, Thomas JL, Bonnegarde-Bernard A, Alder H, Papenfuss TL, Benson DM, Boyaka PN, Ziouzenkova OAldehyde dehydrogenase-1a1 induces oncogene suppressor genes in B cell populations.Biochim Biophys Acta 1833 3218-27 12/1/2013
  • Markowitz J, Wesolowski R, Papenfuss T, Brooks TR, Carson WEMyeloid-derived suppressor cells in breast cancer.Breast Cancer Res Treat 140 13-21 7/1/2013
  • Manickam C, Dwivedi V, Patterson R, Papenfuss T, Renukaradhya GJPorcine reproductive and respiratory syndrome virus induces pronounced immune modulatory responses at mucosal tissues in the parental vaccine strain VR2332 infected pigs.Vet Microbiol 162 68-77 2/22/2013
  • Manickam C, Dwivedi V, Miller J, Papenfuss T, Renukaradhya GJMycobacterium tuberculosis whole cell lysate enhances proliferation of CD8 positive lymphocytes and nitric oxide secretion in the lungs of live porcine respiratory and reproductive syndrome virus vaccinated pigs.Viral Immunol 26 102-8 2/1/2013
  • Julian MW, Shao G, Vangundy ZC, Papenfuss TL, Crouser EDMitochondrial transcription factor A, an endogenous danger signal, promotes TNFα release via RAGE- and TLR9-responsive plasmacytoid dendritic cells.PLoS One 8 e72354 1/1/2013
  • Peng H, Guerau-de-Arellano M, Mehta VB, Yang Y, Huss DJ, Papenfuss TL, Lovett-Racke AE, Racke MKDimethyl fumarate inhibits dendritic cell maturation via nuclear factor κB (NF-κB) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling.J Biol Chem 287 28017-26 8/10/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu