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Patrick L. Green PhD


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Patrick L. Green PhD
Professor / Assoc DeanCollege of Veterinary Medicinegreen.466@osu.edu
444 VMAB 1900 Coffey Road Columbus OH 432101093
Phone:614-688-4899Alternate Phone:614-688-3554Fax: 614-292-6473
  • Viral Oncology
  • Administrative

General Research Interest

Molecular Pathogenesis of Human T-cell Leukemia Virus (HTLV) Molecular Biology of Retrovirus Replication T-cell Activation/Transformation

Research Description

The laboratory of Patrick Green is internationally recognized for their contributions to the understanding of the molecular basis of T-lymphocyte transformation and induction of leukemia/lymphoma and neurological disease by the human T-cell leukemia viruses (HTLVs). The Green lab has three areas of research focus investigating viral and cellular regulators of HTLV gene expression/replication, cellular transformation, and virus survival or persistence in the infected host. 

Current Publications

  • Enose-Akahata Y, Abrams A, Massoud R, Bialuk I, Johnson KR, Green PL, Maloney EM, Jacobson SHumoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individuals.Retrovirology 10 19 2/13/2013
  • Doueiri R, Anupam R, Kvaratskhelia M, Green-Church K, Lairmore MD, Green PLComparative host protein interactions with HTLV-1 p30 and HTLV-2 p28: insights into difference in pathobiology of human retroviruses.Retrovirology 9 64 8/9/2012
  • Yin H, Kannian P, Dissinger N, Haines R, Niewiesk S, Green PLHuman T-cell leukemia virus type 2 antisense viral protein 2 is dispensable for in vitro immortalization but functions to repress early virus replication in vivo.J Virol 86(16) 8412-21 8/1/2012
  • Kannian P, Yin H, Doueiri R, Lairmore MD, Fernandez S, Green PLDistinct transformation tropism exhibited by human T lymphotropic virus type 1 (HTLV-1) and HTLV-2 is the result of postinfection T cell clonal expansion.J Virol 86(7) 3757-66 4/1/2012
  • Zhao T, Satou Y, Sugata K, Miyazato P, Green PL, Imamura T, Matsuoka MHTLV-1 bZIP factor enhances TGF-β signaling through p300 coactivator.Blood 118(7) 1865-76 8/18/2011
  • Lairmore MD, Anupam R, Bowden N, Haines R, Haynes RA 2nd, Ratner L, Green PLMolecular determinants of human T-lymphotropic virus type 1 transmission and spread.Viruses 3(7) 1131-65 7/1/2011