Mamuka Kvaratskhelia PhD


Mamuka Kvaratskhelia PhD
ProfessorCollege of
238 Parks Hall 500 W 12th Avenue Columbus Ohio 43210
Phone:614-292-6091Fax: (614) 292-7766
  • Non-Member

Current Publications

  • Malani N, Aiyer SS, Roth MJ, Bushman FD, Foster MP, Kvaratskhelia M, Larue RC, Plumb MR, Crowe BL, Shkriabai N, Sharma A, DiFiore JBimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes.Nucleic Acids Res 42 4868-81 4/1/2014
  • Aiyer S, Swapna GV, Malani N, Aramini JM, Schneider WM, Plumb MR, Ghanem M, Larue RC, Sharma A, Studamire B, Kvaratskhelia M, Bushman FD, Montelione GT, Roth MJAltering murine leukemia virus integration through disruption of the integrase and BET protein family interaction.Nucleic Acids Res 42 5917-28 1/1/2014
  • Sharma A, Larue RC, Plumb MR, Malani N, Male F, Slaughter A, Kessl JJ, Shkriabai N, Coward E, Aiyer SS, Green PL, Wu L, Roth MJ, Bushman FD, Kvaratskhelia MBET proteins promote efficient murine leukemia virus integration at transcription start sites.Proc Natl Acad Sci U S A 110 12036-41 7/16/2013
  • Engelman A, Kessl JJ, Kvaratskhelia MAllosteric inhibition of HIV-1 integrase activity.Curr Opin Chem Biol 17 339-45 6/1/2013
  • Feng L, Sharma A, Slaughter A, Jena N, Koh Y, Shkriabai N, Larue RC, Patel PA, Mitsuya H, Kessl JJ, Engelman A, Fuchs JR, Kvaratskhelia MThe A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors.J Biol Chem 288 15813-20 5/31/2013
  • Jurado KA, Wang H, Slaughter A, Feng L, Kessl JJ, Koh Y, Wang W, Ballandras-Colas A, Patel PA, Fuchs JR, Kvaratskhelia M, Engelman AAllosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation.Proc Natl Acad Sci U S A 110 8690-5 5/21/2013
  • Eidahl JO, Crowe BL, North JA, McKee CJ, Shkriabai N, Feng L, Plumb M, Graham RL, Gorelick RJ, Hess S, Poirier MG, Foster MP, Kvaratskhelia MStructural basis for high-affinity binding of LEDGF PWWP to mononucleosomes.Nucleic Acids Res 41 3924-36 4/1/2013

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 460 W. 10th Avenue, Columbus, OH 43210 Phone: 1-800-293-5066 | Email: