General Research InterestIn situ correlates of oncogenesis and infectious diseases
Research DescriptionMy research focuses on the correlation of the histologic features and molecular events in cancers and infectious diseases. My work makes extensive use of in situ hybridization and immunohistochemistry techniques to detect proteins, rnas, dnas of interest within intact tissues. Recently, our group has done extensive microrna in situ analyses with co-localization of the putative target(s) and identification of the cell target(s) of interest.
Transinstitutional WorkI collaborate extensively with many members of the cancer center includings drs. Caligiuri, croce, clay marsh, elton, carson, sen, chiocca, otterson. Our work together usually involves blinded analyses of dna/rna/protein targets of interest and then correlation of my in situ work and my collaborators solution phase data. Our group also has extensive collaboration with members of veterinary biosciences and outside institutions (such as the univ cinn and univ alabama).