Pierluigi Porcu MD


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Pierluigi Porcu MD
Assoc ProfessorCollege of Medicineporcu.1@osu.edu
B320 Starling Loving Hall 320 W 10th Avenue Columbus Ohio 43210
Phone:614-293-2268Fax: (614) 366-5970
  • Leukemia Research

Research Description

Dr. Porcu's Clinical interests include: Non-Hodgkin’s Lymphomas; Cutaneous T-Cell Lymphomas, Mycosis Fungoides, Sezary Syndrome, T-cell and NK-cell Lymphomas and his research interests include: T-cell and NK-cell lymphomas; Mycosis Fungoides, Sezary Syndrome, EBV-positive lymphomas.

Current Publications

  • Cohen JB, Geyer SM, Lozanski G, Zhao W, Heerema NA, Hall NC, Nagar VA, Hemminger JA, Jones JA, Porcu P, Christian BA, Baiocchi RA, Maddocks KJ, Flynn JM, Devine SM, Blum KAComplete response to induction therapy in patients with Myc-positive and double-hit non-Hodgkin lymphoma is associated with prolonged progression-free survival.Cancer 120 1677-85 6/1/2014
  • Zelenetz AD, Gordon LI, Wierda WG, Abramson JS, Advani RH, Fisher RI, Glenn MJ, Harris NL, Hoppe RT, Horwitz SM, Kelsey CR, Kim YH, Krivacic S, LaCasce AS, Nademanee A, Porcu P, Andreadis CB, Bartlett N, Bellam N, Byrd JC, Czuczman MS, Fayad LE, Press O, Rabinovitch R, Reddy N, Reid E, Sokol L, Swinnen LJ, Tsien C, Vose JM, Yahalom J, Zafar N, Dwyer M, Sundar HNon-Hodgkin's Lymphomas, Version 2.2014.J Natl Compr Canc Netw 12 916-46 6/1/2014
  • de Silva S, Wang F, Hake TS, Porcu P, Wong HK, Wu LDownregulation of SAMHD1 expression correlates with promoter DNA methylation in Sézary syndrome patients.J Invest Dermatol 134 562-5 2/1/2014
  • Jones JA, Rupert AS, Poi M, Phelps MA, Andritsos L, Baiocchi R, Benson DM, Blum KA, Christian B, Flynn J, Penza S, Porcu P, Grever MR, Byrd JCFlavopiridol can be safely administered using a pharmacologically derived schedule and demonstrates activity in relapsed and refractory non-Hodgkin's lymphoma.Am J Hematol 89 19-24 1/1/2014
  • Fisher RI, Stiff PJ, Unger JM, Cook JR, Constine LS, Couban S, Stewart DA, Shea TC, Porcu P, Winter JN, Kahl BS, Miller TP, Tubbs RR, Marcellus D, Friedberg JW, Barton KP, Mills GM, LeBlanc M, Rimsza LM, Forman SJAutologous transplantation as consolidation for aggressive non-Hodgkin's lymphoma.N Engl J Med 369 1681-90 10/31/2013
  • Cohen JB, Hall NC, Ruppert AS, Jones JA, Porcu P, Baiocchi R, Christian BA, Penza S, Benson DM Jr, Flynn J, Andritsos LA, Devine SM, Blum KAAssociation of pre-transplantation positron emission tomography/computed tomography and outcome in mantle cell lymphoma.Bone Marrow Transplant 48 1212-7 9/1/2013
  • Kaffenberger BH, Kartono Winardi F, Frederickson J, Porcu P, Wong HKPeriocular cutaneous anaplastic large cell lymphoma clearance with brentuximab vedotin.J Clin Aesthet Dermatol 6 29-31 8/1/2013
  • de Silva S, Hoy H, Hake TS, Wong HK, Porcu P, Wu LPromoter methylation regulates SAMHD1 gene expression in human CD4+ T cells.J Biol Chem 288 9284-92 3/29/2013
  • Zelenetz AD, Wierda WG, Abramson JS, Advani RH, Andreadis CB, Bartlett N, Bellam N, Byrd JC, Czuczman MS, Fayad LE, Glenn MJ, Gockerman JP, Gordon LI, Harris NL, Hoppe RT, Pro B, Reddy N, Sokol L, Swinnen L, Tsien C, Vose JM, Yahalom J, Zafar N, Dwyer MA, Naganuma M, National Comprehensive Cancer Network, Horwitz SM, Kelsey CR, Kim YH, Krivacic S, LaCasce AS, Nademanee A, Porcu P, Press ONon-Hodgkin's lymphomas, version 1.2013.J Natl Compr Canc Netw 11 257-72; quiz 273 3/1/2013
  • Gibson HM, Mishra A, Chan DV, Hake TS, Porcu P, Wong HKImpaired proteasome function activates GATA3 in T cells and upregulates CTLA-4: relevance for Sézary syndrome.J Invest Dermatol 133 249-57 1/1/2013
  • Czuczman MS, Fayad L, Glenn MJ, Gockerman JP, Gordon LI, Zelenetz AD, Wierda WG, Abramson JS, Advani RH, Andreadis CB, Bartlett N, Bellam N, Byrd JC, Harris NL, Hoppe RT, Horwitz SM, Kelsey CR, Kim YH, Krivacic S, LaCasce AS, Nademanee A, Porcu P, Press O, Pro B, Reddy N, Sokol L, Swinnen L, Tsien C, Vose JM, Yahalom J, Zafar N, Naganuma M, Dwyer MANon-Hodgkin's Lymphomas, version 3.2012.J Natl Compr Canc Netw 10 1487-98 12/1/2012
  • Mishra A, Liu S, Sams GH, Curphey DP, Santhanam R, Rush LJ, Schaefer D, Falkenberg LG, Sullivan L, Jaroncyk L, Yang X, Fisk H, Wu LC, Hickey C, Chandler JC, Wu YZ, Heerema NA, Chan KK, Perrotti D, Zhang J, Porcu P, Racke FK, Garzon R, Lee RJ, Marcucci G, Caligiuri MAAberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation.Cancer Cell 22 645-55 11/13/2012

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 300 W. 10th Ave. Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu