Viral Oncology (VO) is one of OSUCCC–James' six highly interactive cancer research programs. The programs comprise more than 200 leading scientists from 13 different colleges within OSU and affiliated academic institutions.
Devoted to scientific excellence and specifically tailored to capitalize on the professional strengths and expertise of its members, the VO promotes basic (bench) to translational (therapy) collaborative research. The overarching goals and aims of VO are to foster collaborative research directed at:
1. Elucidating the mechanisms of viral oncogenesis, with an emphasis on:
- Molecular and cellular mechanisms of human T-cell leukemia virus (HTLV-1) associated neoplastic disease
- HPV-associated cancers
- EBV-associated lymphoproliferative disorder
2. Designing improved viral vector-mediated gene transfer technologies and improving oncolytic virotherapy
Thematic research areas include: oncogenic virus proteins and cellular transformation and virus vector development for gene delivery/novel vaccines and targeted therapy.
Leader: Patrick L. Green, PhD