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Melanoma Clinical Trials

With an emphasis on transdisciplinary translational research, the OSUCCC-James facilitates investigator-initiated early phase clinical trials and participates in many cooperative groups.


Protocol No.PITitle
OSU-05127Doreen AgneseA Phase III Multicenter Randomized Trial of Sentinel Lymphadenectomy and Complete Lymph Node Dissection versus Sentinel Lymphadenectomy Alone in Cutaneous Melanoma Patient with Molecular or Histopathological Evidence of Metastases in the Sentinel Node.
OSU-07030William CarsonAnalysis of Micro-RNA Species in Melanoma.
OSU-11099William CarsonIdentifying CT Imaging Biomarkers to Predict Disease Outcome in Melanoma on Anti-angiogenic Therapy
OSU-11166William CarsonA Phase 1, Open-label, Dose-escalation, Safety and Pharmacokinetic Study of CDX-1127 in Patients with Selected Refractory or Relapsed Hematologic Malignancies or Solid Tumors
OSU-0358Frederick DavidorfMolecular Genetic Profiling of Uveal Melanomas
OSU-06036Frederick DavidorfGenetics of Hereditary Uveal Melanoma.
OSU-11024Kari KendraBRF114144: A Rollover Study to Provide Continued Treatment with GSK2118436 to Subjects with BRAF Mutation-Positive Tumor
ECOG-E1609Kari KendraA Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy Versus High-Dose Interferon á-2b for Resected High-Risk Melanoma
OSU-12093Quan LiIncidence of febrile neutropenia for metastatic melanoma patients receiving CVD without prophylactic granulocyte-stimulating factor (GCSF)
OSU-12087Thomas OlenckiA PROSPECTIVE OBSERVATIONAL STUDY OF TREATMENT PATTERNS AND EFFECTIVENESS AND SAFETY OUTCOMES IN ADVANCED BASAL CELL CARCINOMA AND BASAL CELL CARCINOMA NEVUS SYNDROME PATIENTS
OSU-12129Thomas OlenckiThe High-Dose Aldesleukin (IL-2) "Select" Trial: A PROSPECTIVE TISSUE COLLECTION PROTOCOL TO INVESTIGATE PREDICTIVE MODELS OF RESPONSE TO HIGH DOSE IL-2 TREATMENT IN PATIENTS WITH ADVANCED MELANOMA
OSU-12055Alicia TerandoFeasibility and Safety of Minimally Invasive Inguinal Lymph Node Dissection in Patients with Melanoma
OSU-08070Traci WilgusVascular Endothelial Growth Facto Signaling in Skin Carcinogenesis