2012 ISCC Agenda

DRAFT AGENDA

 

Thursday - June 21​

2:00pm​ Registration Open​

Blackwell Inn Lobby

6:45pm​ Welcome
Tatiana M. Oberyszyn, PhD
Associate Professor
Jack C. Geer Endowed Professor
Vice Chair for Academic Affairs
Department of Pathology
The Ohio State University
 
Adam Glick, PhD
Associate Professor
Department of Veterinary and Biomedical Sciences
Co-Chair, Molecular Medicine Program
Penn State University
 
Blackwell Inn Ballroom
7:00pm  ​
Keynote: “The Yin and Yang of Skin Cancer Research
Susan Fischer, MS, PhD
Professor
Department of Carcinogenesis
University of Texas
 
7:30pm​ Welcome Reception
 
 
Blackwell Inn Ballroom
9:00pm​

 Conclusion and Registration Closes 

 

Friday - June 22​ 

​7:00am ​Continental Breakfast
​Pfahl Lobby

​8:00am

​Welcome
Michael Caligiuri, MD
Director and CEO
Comprehensive Cancer Center
James Cancer Hospital and Solove Research Institute
The Ohio State University
 
Pfahl 140
8:15 am​
Identification of Genes, Pathways, and Networks               
Involved in Susceptibility to Skin Tumor Promotion
John DiGiovanni, PhD
Professor
University of Texas
  

8:40 am​
HER2 and ADAM12 in Squamous Cell Carcinoma Progression
Laura Hansen, PhD
Associate Professor
Creighton University
 
9:05am​   
DeltaNp63 Mediate Malignant Progression of Mouse Skin Tumors                                               
Wendy Weinberg, PhD
Chief
FDA
  
9:30am​
p63 Mediated Regulation of Vitamin D Receptor and
PTEN dictates Cellular Fate
Madhavi Kadakia, PhD
Associate Professor
Wright State University
 
9:55am​ Session Discussion
 
 

10:10a   ​

 

Morning Break
 
Pfahl 140 Lobby
Session Two - Inflammatory Cells and Skin Cancer
Session Chair:  Stephen Ulrich, PhD
 
10:30am​    
PAF, Mast Cells and Immunes Suppression: A Path to Skin Cancer?
Stephen Ulrich, PhD                                                          
Professor
MD Anderson Cancer Center 
 
Pfahl 140
10:55am​
Pro-Inflammatory Regulators in UV-Induced Skin
Carcinogenesis                                                     
Traci Wilgus, PhD
Assistant Professor
The Ohio State University 
 
11:20am​
Immune Cell Infiltrates During Lip Cancer  Progression 
Role of Mast Cells on Promoting an Immunosuppressive
Microenvironment
Gina Rojas-Rudolph, DDS, PhD.
Associate Professor
University of Concepcion, Chile
 
11:45am​
Session discussion 
 
12:10pm​ Lunch
 
 

Blackwell Inn Ballroom

 

Session Three: Stem Cells and Cancer Stem Cells in the Skin
Session Chair:  Irina Budunova, MD, PhD

1:30pm​
Nanog, Keratinocyte Stem Cells and Tumor        
Development 
Dean Tang, MD, PhD
Professor
MD Anderson Cancer Center 
 
Pfahl 140
1:55pm​
Role of the Glococorticoid Receptor in Skin Carginogenesis and Stem Cell Maintenance
Irina Budunova, MD, PhD
Associate Professor
Northwestern University
 
2:20pm​
Bone Marrow Cells and Skin Carcinogenesis                                                                      
Rebecca Morris, PhD
Professor
The Hormel Institute
 
2:45pm​
Characterization of the Epidermal Touch Dome Progenitor Niche
David Owens, PhD
Assistant Professor
Columbia University 
 
3:10pm​ Connections Between Wound Healing and Skin Cancer
Sunny Wong
Assistant Professor
University of Michigan
 
3:30pm​

Session Discussion

3:45pm​ Afternoon Break
 
 
Pfahl 140 Lobby

Session Four: Critical Genes and Signaling Pathways Part II
Session Chair:  Mitch Denning, PhD

4:10pm
Role of Protein Kinase C Delta in UV Radiation DNA Damage Response
Mitch Denning, PhD
Professor
Loyola University 
 
Pfahl 140
4:35pm​
ATF2 Skin Cancer – Oncogene or Tumor Suppressor  
Ze’ev Ronai, PhD
Professor
Sanford Burnham Medical Research Institute 
 
5:00pm​
Characterization of the Microtubule Regulatory Protein, Stathmin 1, in Skin and Cutaneous Tumors of Human and Mouse Orgin
Carol Trempus, MS
Biologist
NIEHS 
 
5:25pm​ Session Discussion
 
 
5:40pm​ Conclusion
 
 
6:45-7:15​ Poster Drop-off 
 
7:15pm​ Poster Session and Reception 
 
Physics Research Building
9:00pm​ Conclusion
 
 

Saturday - June 23​

 

7:00am​ Continental Breakfast
 
 
Pfahl 140 Lobby

Session Five: Critical Genes and Signaling Pathways Part III
Session Chair:  Zigang Dong, MD, Phd
 

8:00am​
Using TetON-HIF-1 Transgenic Mice to Dissect Molecular and Neovascularization Control
Jeffrey Arbeit, MD
Professor
Washington University St. Louis 
 
Pfahl 140
8:25am​
Major Signaling Genes Required for Solar UV-Induced Skin Cancer
Zigang Dong, MD, PhD
Professor
The Hormel Institute
 
8:50am​
A Novel Animal Model of Transcription Factor Function in Epidermis
Richard Eckert, PhD
Professor
University of Maryland 
 
9:15am​

Functional Characterization of Individual Patients’ HSNCC
Responses to Small Molecule Inhibitors

Molly Kulesz-Martin, PhD
Professor
Oregon Health and Science University

 

9:40am​
Trim32 Enhances the Growth of Papillomas in Mice
During Two Stage Chemical Carcinogenesis 
Aaron Wortham, BS
Graduate Research Assistant
Oregon Health and Science University 
 
10:00am​ Session Discussion
 
 
10:15am​ Morning Break
 
 
Pfahl 140 Lobby
Session Six: The Genetics of Skin Cancer 
Session Chair:  Dennis Roop, PhD
 ​
10:40am​
Allele Specific Somatic Alterations in cSCCs Uncover Tumor Susceptibility Genes
Amanda Toland, PhD
Assistant Professor
The Ohio State University 
 
11:05am​
Skin Karyometry to Predict the Natural History of Squamous Cell Carcinoma
David Alberts, MD
Professor
University of Arizona
 
11:30pm​ Lunch
 
 
Grand Ballroom
1:00pm​
Myc, Aurora Kinase-A and Mutant p53R172H cooperate in a
Mouse Model of Metastatic Skin Carcinoma

Dennis Roop, PhD
Professor and Director
University of Colorado
 
Pfahl 140
1:25pm​
MicroRNAs in Skin Biology and Their Role in Skin Cancer
Thomas Andl, PhD 
Assistant Professor
Vanderbilt University Medical Center
 
1:45pm​ Session Discussion 
 

Session Seven: Critical Genes and Signaling Pathways Part IV
Session Chair:  Adam Glick, PhD

2:15pm​
TGFβ1 Inflammation and Cutaneous Dendritic CellAdam Glick, Ph.D
Associate Professor
Penn State University
 
Pfahl 140
2:40pm​
Slug and Calprotein: An Unexpected Pair
Donna Kusewitt, DVM, PhD, ACVP
Professor
MD Anderson Cancer Center
 
3:05pm

Afternoon Break

  

3:30pm​
HGF, Cutaneous Inflammation and Skin Cancer:
A Model with Two Tales
Christophe Cataisson, PhD
Staff Scientist
NCI Center for Cancer Research
 
3:55pm​
Elevated Polyamine Levels Generate an Immunosuppressive Oncogenic Microenvironment
Susan Gilmour, PhD
Professor
Lankenau Institute for Medical Research
 
4:20pm​
DelatNp63alpha Regulated Keratinocyte Proliferation
by Controlling PTEN Expression and Localization
Mary Leonard, BS
Graduate Research Assistant
Wright State University
 
4:40pm​ Session Discussion 
 
5:10pm Conclusion 
 
Free Night
 
 

Sunday - June 24

 

7:30am​ Full Breakfast
 
 
Blackwell Inn Ballroom
Session Eight: Inflammatory Pathways and Skin Cancer Part II
Session Chair:  Ervin Epstein, MD
 

 

9:00am​
Tumor Regression by the Dietary Flavonoid Fisetin in a 3-D Melanoma Model 
Hasan Mukhtar, PhD
Professor
University of Wisconsin

Pfahl 140
9:25am​
Bioactive Phytochemicals-Based Strategies for Prevention of Skin Cancer
Santosh Katiyar, PhD
Professor
University of Alabama Birmingham

9:50am​
Targeting of UV Induced Signal Transduction Pathways 
for the Chemoprevention of Skin Cancer
Tim Bowden, PhD
Professor
The University of Arizona Cancer Center
 
10:15am​
AMPK-mTOR Axis as a Key Target for Chemoprevention
of UV-Induced Skin Cancer
Jill Pelling, PhD
Professor
Northwestern University
 
10:40am​ Morning Break
 
 
11:00am​
Sulforaphane Analogue 1-Isothiocyonato-7-(Methylsulfinyl)-
Heptane is a Potent Modulator of Chemoprevention
Pathways Relating to AP-1 Inhibition and Nrf2 Stimulation                                                      
Sally Dickinson, PhD.
Research Assistant Professor
University of Arizona Cancer Center
 
Pfahl 140
11:20am​
Advances in the Treatment of Melanoma
Kari Kendra, MD
Associate Professor
The Ohio State University
 
 
11:45am​
Treatment of BCCs in Gorlin Patients with Vismodegib
Ervin Epstein, MD
Senior Scientist
Children's Hospital Oakland Research Institute 
 
12:10pm​ Session Discussions / Conclusions 
 
12:30pm​ Snacks to Go 
 
Pfahl Lobby

 

 

 

 

 

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) 460 W. 10th Avenue, Columbus, OH 43210 Phone: 1-800-293-5066 | Email: jamesline@osumc.edu