The GSR enables researchers to use the expertise and state-of-the-art genomics services found at both institutions. Led by scientists from the OSUCCC – James and Nationwide Children’s IGM, this shared resource provides high-throughput genomics technologies along with consultation and assistance in experimental design, troubleshooting, training and development of novel methodologies.
Nationwide Children’s IGM director Richard Wilson, PhD, who also is a professor in the Department of Pediatrics at Ohio State, serves as director of the GSR, focusing on next-generation sequencing (NGS) and overseeing development of new technologies at both locations. The team at Nationwide Children’s can assist investigators with multiple aspects of NGS, including library preparation, sequence generation and data analysis.
Amanda Toland, PhD, associate professor in the Department of Cancer Biology and Genetics at Ohio State, is co-director of the GSR. She is responsible for the direction and development of all non-NGS services (Sanger sequencing, cell line verification, gene expression profiling, microarrays, QC and Nanostring) and oversees NGS library generation, including single cell libraries, at Ohio State.
Technical directors for the GSR are Pearlly Yan, PhD, research assistant professor in the Division of Hematology at Ohio State and member of the Leukemia Research Program at the OSUCCC – James; and Vincent Magrini, PhD, research assistant professor in the Department of Pediatrics at Ohio State and senior director in the IGM.
Faculty leaders at the OSUCCC – James and Nationwide Children’s IGM believe that, through the GSR, the institutions have formed a centralized, comprehensive hub for genomic research in Ohio and beyond. They anticipate that this collaborative service will enhance opportunities for more National Cancer Institute-sponsored research.
For more information about services available through the GSR, call (614) 247-8185 or email amanda.toland@osumc.edu.
For more information about high-throughput sequencing and library generation, call (614) 685-9164 or email pearlly-yan@osumc.edu.
To learn more about services offered through the lab at Nationwide Children’s IGM, call (614) 355-3530 or email vincent.magrini@nationwidechildrens.org or amy.wetzel@nationwidechildrens.org.
NOTE: The Shared Resources and core facilities at the OSUCCC – James are a National Cancer Institute-recognized network of specialized service facilities that enhance an investigator’s ability to conduct cancer research by reaching across medical disciplines and offering: expert leadership and training; clinical, administrative and technical support; and state-of-the-art instrumentation. This issue of Frontiers highlights the Genomics Shared Resource (GSR).