Under the direction of Pravin Mishra, PhD, MBA, a member of the Translational Therapeutics Program at the OSUCCC – James, this shared resource helps researchers translate basic science findings to the clinical setting and vice-versa to improve diagnosis and treatment strategies for patients with cancer.
Toward this goal, the CTSSR offers multiple laboratory services, including clinical sample receiving, processing, storage and distribution; automated DNA, RNA, miRNA purification from cells, blood, FFPE or fresh frozen tissue samples; circulating nucleic acid (DNA, miRNA) purification from plasma, urine and other bodily fluids; and many others.
The CTSSR serves as a central repository for specimens collected from patients on clinical trials and is responsible for processing the tissue for any number of downstream analyses. In addition to developing novel assays, the CTSSR partners with other OSUCCC shared resources to utilize available technologies such as next-generation sequencing, RNA expression analysis and proteomics. In these situations, the CTSSR obtains and prepares the patient samples for downstream analyses and then collects and organizes the data.
This shared resource also helps identify and develop partnerships among investigators and pharmaceutical companies to gain access to new drugs and compounds, and to provide corresponding correlative testing and analyses for cancer studies. For more information about services available through the CTSSR, call 614-366-9041 or email Pravin.Mishra@osumc.edu.
NOTE: The Shared Resources and core facilities at the OSUCCC – James constitute a National Cancer Instituter-recognized network of specialized service facilities that enhance an investigator’s ability to conduct cancer research by offering: expert multidisciplinary leadership and training; clinical, administrative and technical support; and state-of-the-art instrumentation. The CTSSR highlighted here is one of 20 OSUCCC – James Shared Resources.