Ohio State researchers have found a new target in their efforts to develop better treatments for brain tumors. OSUCCC – James experts are preparing to conduct a clinical trial that targets a protein called PRMT5 that is sometimes used by cancer cells to drive brain cancers. By working to inhibit these proteins, researchers hope to shut down cancers as well, according to Vinay Puduvalli, MD. “A new target, a new way of attacking the tumor, something that fundamentally hits the tumor at the stem cell level and then being able to translate that — that’s very hopeful for me,” he says.