The internationally recognized experts at the OSUCCC – James believe the best way to treat patients and manage their disease successfully is to be at the forefront of delivering the latest, most effective treatments available and by working with nationally and internationally renowned experts to develop the newest and best acute myeloid leukemia (AML) treatments and programs.

Because these renowned subspecialists understand that AML is a complex disease, they use the most effective means of treating patients through an expert team approach from across multiple medical disciplines. These teams also run groundbreaking studies, and through detailed observations, evaluate the latest treatments and targeted therapies for each patient.

The OSUCCC – James team of experts – who are central Ohio’s only referral center for treating acute leukemia – analyzes the genetic composition of each individual’s leukemia to determine the best possible treatment, offering improved outcomes, faster responses and fewer side effects.

If you’ve been diagnosed with acute myeloid leukemia, would like a second opinion or would like to speak with a leukemia specialist, please call The James Line at 800-293-5066 or 614-293-5066 to make an appointment.

Treatment for Acute Myeloid Leukemia

The OSUCCC – James is a leader in offering some of the world’s most advanced, sophisticated treatments for leukemia patients.

Acute myeloid leukemia (AML) treatment usually takes place in two phases:

1. Remission Induction

The first treatment phase, and it’s designed to destroy leukemia cells and put the cancer into remission. This treatment usually begins with chemotherapy.

After the patient’s leukemia is in remission, a second phase of therapy begins.

2. Post-remission Therapy or Remission Continuation Therapy

Is the second phase, and this is designed to kill any remaining leukemia cells and prevent a relapse.

Patients might also have radiation therapy (which uses X-rays to destroy cancer cells) or a stem cell transplant. A stem cell transplant replaces abnormal blood-forming cells or cells that are killed during chemotherapy. The OSUCCC – James is the only central Ohio hospital to offer stem cell transplantation.

Once the OSUCCC – James experts complete initial treatments, one or more of the following therapies may be recommended for AML patients:

Maintenance Therapy

After initial treatment, patients will sometimes receive maintenance therapy to help prolong remission. Because there is always a chance that the cancer may come back or progress, it is very important to see your doctor regularly for follow-up exams.

The OSUCCC – James subspecialists closely monitor patients with AML because of their weakened bone marrow activity and increased likelihood to get infections.

Targeted Therapies

Targeted therapies are drugs that attack cancer cells without destroying healthy surrounding cells. These therapies are particularly effective in treating AML with fewer harmful side effects than with traditional chemotherapy.

Leukemia Biomarker Testing

The OSUCCC – James research experts recently identified an important marker (gene identifier) for AML, called microRNA-155 — a discovery that led the OSUCCC – James subspecialists to develop a new targeted therapy that is particularly effective in treating AML.

Acute Myeloid Leukemia & Clinical Trials

For leukemia patients, clinical trials mean hope.

The OSUCCC – James has hundreds of open clinical trials at any given time, with some of the world’s latest discoveries available to clinical trial patients right here in Columbus, Ohio. In fact, patients have access to more of this nation’s leading-edge, targeted treatments and drugs than at most hospitals in the region.

Patients can enter clinical trials before, during or after starting their individual treatments.

The OSUCCC – James is one of only a few U.S. cancer centers funded by the National Cancer Institute to conduct phase I and phase II clinical trials on novel anticancer drugs. These trials go only to centers that demonstrate an exemplary capacity for research and clinical care, the expertise to deliver the latest in treatments and the infrastructure to interpret and track treatment results.

If you’ve been diagnosed with acute myeloid leukemia, would like a second opinion or would like to speak with a leukemia specialist, please call The James Line at 800-293-5066 or 614-293-5066 to make an appointment.

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The James Cancer Hospital and Solove Research Institute

460 West 10th Avenue

Columbus, Ohio 43210

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