There is no such thing as routine bone and spine sarcoma. Every patient’s cancer is different, with different, individually unique genes and molecules driving that specific cancer.

At the OSUCCC – James, our bone and spine sarcoma sub-specialists are world-renowned cancer experts who focus solely on bone and spine sarcoma and who reach across medical disciplines (medical oncologists, surgical  oncologists, radiation oncologists, pharmacists and more) to design the very best treatment plan and therapies to target each patient’s specific cancer.

Not only is the OSUCCC – James is also among the top five sarcoma programs in the country, it is also the only central Ohio provider for patients with recurrent sarcoma.

And by offering access to some of the country’s most advanced clinical trials right here at the OSUCCC – James, patients know that additional options, when needed, are often available for their treatment and care.

About Bone & Spine Sarcoma

Sarcoma is a rare cancer that forms in the the body’s fat cells; soft tissues such as muscles, nerves or tendons; blood vessels; tissues that surround joints; the spinal cord; or in the bones.

Bones are made up of different types of tissues, including the hard tissue on the outside, flexible cartilage, and fibrous tissue surrounding the joints and bone marrow, which is the soft, sponge-like material found inside the bones.

The spinal cord is a long column of nerve tissue that connects the brain stem to important nerves throughout the body. It is covered by layered tissue called membranes, which are surrounded by the backbones, or vertebrae.

(Source: National Cancer Institute)

Types of Bone & Spine Sarcoma

There are several different types of bone and spine sarcomas. These include:

Osteosarcoma (Bone Sarcoma)

In the bones, sarcomas usually start in cells called osteoblasts, that form new bone tissue. Tumors usually form in the knee or upper arm.

Osteosarcomas can be further classified into subtypes based on the types of cells that make up the tumor.

Ewing Sarcoma

Ewing sarcoma primarily affects children and adolescents and it can form in cells in either bones or soft tissues. Ewing sarcoma and osteosarcoma are two types of sarcomas that can form in or near the spine.

A type of Ewing sarcoma called primitive neuroectodermal tumor, or PNET, develops from early or immature cells (stem cells). PNET is more likely than some types of sarcoma to form in the area of the spine or pelvis.


Chondrosarcoma, which affects older adults, begins in cells that make up the cartilage tissue found at the ends of bones or in the joints lining. These tumors usually form in the pelvis, upper leg and shoulder.

(Source: National Cancer Institute)

Bone & Spine Sarcoma Symptoms


Osteosarcoma symptoms include:

  • Swelling over a bone or bony part of the body
  • Pain in a bone or joint
  • A bone that breaks for no known reason

Ewing Sarcoma

Ewing sarcoma symptoms include:

  • Pain and/or swelling, usually in the arms, legs, chest, back or pelvis 
  • A lump (which may feel soft and warm) in the arms, legs, chest or pelvis
  • Fever for no known reason
  • A bone that breaks for no known reason

(Source: National Cancer Institute)

Having these symptoms does not necessarily mean you have spine or bone sarcoma. But if you have symptoms, you should tell your doctor, especially if symptoms have continued for longer than a few weeks.

If you’ve been diagnosed with a bone or spine sarcoma, would like a second opinion or would like to speak with a sarcoma specialist, please call The James Line at 800-293-5066 or 614-293-5066 to make an appointment.

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The James Cancer Hospital and Solove Research Institute

460 West 10th Avenue

Columbus, Ohio 43210

800-293-5066 or 614-293-5066

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