Cancer is complex — there is no routine cervical cancer, nor is there ever a routine way to treat it. 

The OSUCCC – James physicians are nationally and internationally renowned in research and patient care for their one particular cancer. Because of that expertise and understanding of cancer’s complexities and how it acts and reacts differently in each person, the very best outcomes — and the most effective means of treating cancer patients — come from a team approach. 

At the OSUCCC – James, cervical cancer patients have a team of experts that includes medical gynecologic oncologists, surgical oncologists, radiation oncologists, geneticists, nutritionists and more. Also on that team are cervical cancer researchers who help sequence tumors to identify key molecules that fuel each patient’s cancer and who then develop drugs that target only those particular molecules. Many of our experts also help write the national clinical guidelines for treatments.

As one of only a few cancer centers in the country funded by the National Cancer Institute to conduct both phase I and phase II clinical trials, the OSUCCC – James offers patients access to more clinical trials than nearly any other cancer hospital in the country and to more of the latest, most targeted, most effective treatment options — many that are available nowhere else but at the OSUCCC – James. 

There are several types of treatment for cervical cancer. The OSUCCC – James team of subspecialists determine the best treatment for each patient based on his or her specific, individual cervical cancer. Patients may receive one treatment or a combination of treatments. 

Treatment for Cervical Cancer

Cervical Cancer Surgery 

Our gynecologic cancer doctors were among the first in the nation certified to perform minimally invasive robotic surgery.

That specialized treatment results in smaller incisions, better outcomes and less scarring for our cervical cancer patients. 

OSUCCC – James is one of the leading cancer hospitals in the country for robotic cervical cancer surgery. One procedure we’ve pioneered — sentinel lymph node dissection — creates less postsurgical swelling in the legs. In fact, we perform more of these procedures than any other hospital in Midwest. 

Types of surgery available to treat cervical cancer are as follows:

Hysterectomy (Total, Modified & Radical)

A hysterectomy is a type of surgery to remove the uterus and cervix. A radical hysterectomy may remove other tissues including ovaries and fallopian tubes. There are many different techniques used to perform this surgery. Your doctor will help you decide which one is right for you.

Bilateral Salpingo-Oophorectomy

A type of surgery that removes both ovaries and both fallopian tubes.

Pelvic Exenteration

A type of surgery to remove the lower colon, rectum and bladder along with the cervix, vagina and ovaries. Plastic surgery is sometimes used after this surgery to repair or replace missing tissues.

Cryosurgery or Cryotherapy

A type of treatment that freezes and thereby destroys abnormal tissue. This type of treatment is often used for early stage cervical cancer, like stage 0 (carcinoma in situ). 

Laser Surgery

A type of procedure that uses a laser beam (a narrow beam of intense light) as a knife to make precise cuts in tissue or to remove small tumors.

Loop Electrosurgical Excision Procedure

A type of treatment that uses electrical current passed through a thin wire loop as a knife to remove abnormal tissue or cancer.

(Source: National Cancer Institute )

Radiation Therapy

Radiation therapy uses high-energy X-rays or other radiation to destroy cancer cells. The radiation is aimed at the cancer from outside the body or delivered to the cancer inside the body through tiny seeds that are usually directed to the organ using catheters, or thin tubes. 

Radiation therapy usually is used to treat cervical cancers that have spread beyond the cervix or very large tumors.

The radiation oncologists at OSUCCC – James are constantly improving radiation techniques and procedures so that tumors are targeted more precisely with the least damage to healthy cells.


Chemotherapy drugs stop the growth of cervical cancer cells by killing the cells or by stopping them from making new cells. The way the chemotherapy is given depends on the type and stage of your cervical cancer. A low-dose chemotherapy is often given during the time of external radiation therapy. 

OSUCCC – James offers the most advanced, targeted chemotherapy options for cervical cancer, including clinical trial options. We also provide support and care if you experience side effects of treatment, including nausea and constipation. 

Cervical Cancer Research & Clinical Trials 

For cancer patients, clinical trials mean hope. Hope for a cancer-free world and for better, more targeted ways to prevent, detect, treat and cure individual cancers. Patients can enter clinical trials before, during or after starting their cancer treatment.

The OSUCCC – James has more than 500 open clinical trials at any given time, with some of the world’s latest discoveries available to clinical trial patients right here in Columbus, Ohio. In fact, patients have access to more cancer clinical trials here than at nearly any other hospital in the region as well as access to some of the most advanced, targeted treatments and drugs available. 

The OSUCCC – James is one of only a few U.S. cancer centers funded by the National Cancer Institute (NCI) to conduct phase I and phase II clinical trials on novel anticancer drugs. These trials go only to centers that demonstrate an exemplary capacity for research and clinical care, the expertise to deliver the latest in treatments and the infrastructure to interpret and track treatment results. 

Additionally, Ohio State has nearly 300 cancer researchers dedicated to understanding what makes each patient’s cancer grow, move, metastasize or reoccur. Because of the OSUCCC – James’ NCI phase I and phase II approvals, these experts can move research discoveries into clinical trials and make them available to patients sooner.

If you have received a cervical cancer diagnosis, or if you want a second opinion or just want to speak to a cervical cancer specialist, we are here to help you. Call 800-293-5066 or 614-293-5066 to make an appointment.

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The James Cancer Hospital and Solove Research Institute

460 West 10th Avenue

Columbus, Ohio 43210

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