There is no routine cancer, and every person’s disease is different, with individually unique genes and molecules driving that disorder. The internationally renowned specialists and subspecialists at the OSUCCC – James believe the best way to treat patients and manage their disease successfully is to deliver the latest treatments available.

Because these renowned experts understand that cancer is complex, they use the most effective means of treating patients through a coordinated team approach that reaches across multiple medical disciplines (radiation oncologists, surgical oncologists, medical oncologists, molecular and biological pathologists, genetic scientists and more) to design the very best treatment plan and therapies targeting each patient’s specific cancer — offering improved outcomes, faster responses and fewer side effects.

The OSUCCC – James team also runs groundbreaking studies, and, through detailed observations, evaluates the latest treatments and targeted therapies.

If you have been diagnosed with cancer and would like a second opinion, or if you would like to speak with a radiation oncology specialist, please call The James Line at 800-293-5066 or 614-293-5066 to make an appointment.

Treatment Options

As a National Cancer Institute (NCI)–designated comprehensive cancer center, the OSUCCC – James offers patients access to novel therapies that may not be available anywhere else in the United States. This includes:

The Varian TrueBeam Linear Accelerator

In the hands of the OSUCCC – James team of radiation oncology experts, the Varian TrueBeam Accelerator gives these specialists and subspecialists on multidisciplinary teams the power to manage highly challenging cancers with unparalleled ease and precision anywhere in the body. This includes the lung, abdomen, breast, and head and neck. It is a radically new solution that is faster and more powerful, and it seamlessly integrates respiratory gating, imaging and treatment techniques.

The TrueBeam rotates around the patient to deliver a prescribed radiation dose from virtually any angle. It combines imaging, beam delivery and sophisticated RapidArc technology to target tumors accurately and precisely as well as with great speed. Real-time imaging tools allow the experts to "see" the tumor they are about to treat, and respiratory gating enables the team to synchronize beam delivery with patient respiration.

TheTrueBeam Linear Accelerator is equipped with Brainlab technology, including ExacTrac® Frameless Radiosurgery, which replaces frame-based treatments. This offers highly accurate delivery of single-fraction treatments for improved patient comfort.

The TrueBeam is capable of all conventional radiation therapies, Image Guided Radiation Therapy (IGRT) and Intensity Modulated Radiation Therapy (IMRT). Automated technologies ensure the patient receives the same focused radiation directly to the tumor each day of treatment, making treatment easier, safer and more effective.

The OSUCCC – James team of experts offers cancer patients the most advanced tumor-targeting technologies available today, sometimes even combining the power and precision of the TrueBeam Linear Accelerator with conventional radiation therapies, including:

External Beam Radiation Therapy

Delivers high energy X-rays that easily penetrate the body to reach the tumor. The treatment is delivered with a linear accelerator (Linac). Also called conformal radiation therapy, the Linac rotates to several different angles around the patient to deliver individually shaped beams to the tumor target.

These beams are closely adjusted (conformed) to converge on the tumor to deliver the planned dose of radiation (conformal radiation therapy).

In early 2015, the OSUCCC – James became the only central Ohio facility to offer Calypso 4D image-guided external beam radiation, which further enhances targeting prostate cancer and soft tissue tumors.

Intensity Modulated Radiation Therapy (IMRT)

A type of external beam radiation therapy that delivers escalated doses that “paint” radiation around the tumor, allowing higher radiation doses than with conformal therapy while also protecting healthy tissues even more effectively. IMRT is quickly becoming the first choice in head-and-neck and prostate cancers, and it is expanding to the treatment of many other tumors as well.

Stereotactic Body Radiation Therapy (SBRT)

An image-guided radiation therapy that delivers high doses of radiation to selected body sites with fewer treatments. It is particularly effective for treating inoperable early-stage lung cancer, liver tumors, spinal tumors and other cancers. Experts at the OSUCCC – James, the only central Ohio facility to offer SBRT, have published multiple scientific articles about SBRT advantages, and they have contributed to the only textbook dedicated to using SBRT to treat spinal tumors.

Image-Guided Radiation Therapy (IGRT)

Combines IMRT with precise CT (computed tomography) imaging. This allows higher doses of radiation to be targeted to the tumor while protecting the surrounding healthy tissue and reducing treatment-related side effects and complications.

Stereotactic Radiosurgery (SRS) and Fractionated Stereotactic Radiotherapy (FSRT)

SRS is a single large dose of radiation delivered with millimeter precision to a small tumor target, sometimes using the Gamma Knife radiosurgery option, available only at the OSUCCC – James. SRS can be delivered in multiple doses with the Linac-based delivery system, and this method is preferred for larger tumors or tumors located close to critical healthy tissues.

While a single large dose of radiation can be given only to relatively small targets, larger tumors can be treated with similar high precision using FSRT. Special attachments are added to the Linac-based system and the treatments can be spread out over several days.

Brachytherapy, Image-Guided Brachytherapy 

Delivers radiation from the inside of the patient or tumor. Radioactive “seeds” are placed within or around a tumor and may remain in the tumor region temporarily or permanently (if left permanently, the radioactivity incrementally decreases over time).

The OSUCCC – James offers a range of brachytherapy options, such as:

  • Temporary high-dose-rate (HDR) implants that are inserted during an outpatient procedure.
  • Temporary low-dose-rate (LDR) implants that are inserted as an inpatient procedure.
  • Image-guided brachytherapy using CT, MRI or both. This enables the specialists to deliver a highly personalized prescription dose of radiation directly to the patient’s tumor area.

The OSUCCC – James is the only central Ohio facility to offer MRI image-guided brachytherapy.

Intraoperative Radiation Therapy (IORT)

Used for those patients whose tumors are closely positioned next to healthy tissues. Often, the only way to protect those healthy tissues from radiation is to deliver radiation therapy during surgery, when these healthy tissues can be temporarily moved out of the way. The OSUCCC – James is one of a few centers in the country to offer this radiation therapy with two options that can be tailored to each patient's individual situation: electron beam IORT, with a dedicated Linac in the operating room (Mobetron); and intraoperative high-dose-rate brachytherapy, with custom-designed brachytherapy delivered during surgery to the tumor bed.

Vision RT 

This form of radiation therapy, available in central Ohio only at the James Cancer Hospital and Solove Research Institute and the Stefanie Spielman Comprehensive Breast Center, allows optical surface tracking for even more precise radiation delivery.

Proton Therapy

The OSUCCC – James is collaborating with Nationwide Children’s Hospital to introduce the first proton therapy treatment facility to central Ohio in 2021, offering state-of-the-art radiation oncology treatment for adult and pediatric cancer patients all in one place.

Proton therapy is an advanced radiation treatment that uses protons (positively charged particles) instead of X-rays to kill cancer cells.

Highly trained OSUCCC – James radiation oncology specialists use a dedicated machine to delivers a high-energy proton beam painlessly through the skin from outside the body.

Proton therapy can be used alone or in combination with other therapies to treat several localized cancers, including prostate, brain, head and neck, lung, spine and gastrointestinal in adults, as well as brain cancer, lymphoma, retinoblastomas and sarcomas in children.

If you have been diagnosed with cancer and would like a second opinion, or if you would like to speak with a radiation oncology specialist, please call The James Line at 800-293-5066 or 614-293-5066 to make an appointment.

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The James Cancer Hospital and Solove Research Institute

460 West 10th Avenue

Columbus, Ohio 43210

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