At the OSUCCC – James, cancer researchers continually focus on studying prostate cancer prevention, diagnosis, treatment and cure. In fact, the OSUCCC – James is consistently paving the way in leading-edge therapies and discoveries, leading to even more highly targeted care and treatment.

Recent studies suggest that prostate cancer risk may actually be reduced through nutritional strategies, and in some cases, chemoprevention. Couple that with world-renowned diagnostic experts and the most advanced diagnostic techniques to enable physicians to detect prostate cancer at an earlier stage, and patients are experiencing exceptional outcomes and results.

Screening for Prostate Cancer 

Cancer screening exams can help find prostate cancer at its earliest stage, when the chances for successful treatment and optimal outcomes are greatest. These tests are usually done when a patient is healthy and has no specific symptoms.

Not only are expert cancer researchers at the OSUCCC – James continually working to detect and diagnose prostate cancer early, but they are also developing additional tests to detect and diagnose cancer even earlier. 

Prostate cancer screening at the OSUCCC – James includes: 

Prostate-Specific Antigen (PSA)

Prostate-specific antigen, or PSA, is a protein produced by the prostate gland. The PSA test measures the level of PSA in a man’s blood. For this test, a blood sample is sent to a laboratory for analysis. The blood level of PSA is often elevated in men with prostate cancer, though there is no specific normal or abnormal level of PSA in the blood. 

Digital Rectal Exam (DRE)

A digital rectal exam (DRE) is an exam of the rectum. A doctor or nurse inserts a lubricated, gloved finger into the lower part of the rectum to feel the prostate for lumps or anything else that seems unusual.

Prostate Cancer Risk Factors

Anything that increases your chances of developing prostate cancer is called a risk factor. The following factors may play a role in the development of prostate cancer:


Prostate cancer is rare in men younger than 50 years of age. The chance of developing prostate cancer increases as men get older.

Family History of Prostate Cancer

A man whose father, brother or son has had prostate cancer has a higher-than-average risk of prostate cancer.


Prostate cancer occurs more often in African American men than in white men. African American men with prostate cancer are more likely to die from the disease than white men with prostate cancer.


The prostate needs male hormones to work the way it should. The main male sex hormone is testosterone. Testosterone helps the body develop and maintain male sex characteristics.

Testosterone is changed into dihydrotestosterone (DHT) by an enzyme in the body. DHT is important for normal prostate growth but can also cause the prostate to get bigger and may play a part in the development of prostate cancer.

Vitamin E

The Selenium and Vitamin E Cancer Prevention Trial (SELECT) found that vitamin E taken alone increased the risk of prostate cancer. The risk continued even after the men stopped taking vitamin E.

Folic Acid

Folate is a kind of vitamin B that occurs naturally in some foods, such as green vegetables, beans and orange juice. Folic acid is a man-made form of folate that is found in vitamin supplements and fortified foods, such as whole-grain breads and cereals. A 10-year study showed that the risk of prostate cancer was increased in men who took 1 milligram (mg) supplements of folic acid. However, the risk of prostate cancer was lower in men who had enough folate in their diets.

Dairy & Calcium

A diet high in dairy foods and calcium may cause a small increase in the risk of prostate cancer. 

(Source: National Cancer Institute)

Not everyone with risk factors will get prostate cancer. But having certain risk factors may increase your risk of developing the disease. If you are at high risk for prostate cancer, talk to your doctor about tests to find out if you have early signs of the disease.

If you’ve been diagnosed with prostate cancer, would like a second opinion or would like to speak with a prostate cancer specialist, please call The James Line at 800-293-5066 or 614-293-5066 to make an appointment.

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The James Cancer Hospital and Solove Research Institute

460 West 10th Avenue

Columbus, Ohio 43210