There is no such thing as routine testicular cancer. Every patient’s testicular cancer is different, with different, individually unique genes and molecules driving that specific cancer.

At the OSUCCC – James, our testicular cancer specialists are world-renowned cancer experts who focus solely on testicular cancer and who reach across medical disciplines (urologists, oncologists, surgeons, radiologists, pharmacists and more) to design the very best treatment plan and therapies to target each patient’s specific testicular cancer.

In fact, our unique Multidisciplinary Testicular Cancer Clinic offers all newly diagnosed testicular cancer patients an on-site, thorough evaluation and treatment-options review with experts from urologic radiation oncology, surgical oncology and medical oncology – all on the same day – so that together, the patient and the experts can decide on the best personalized treatment option.

And by offering access to the country’s most advanced clinical trials right here at the OSUCCC – James, patients know that additional options, when needed, are often available for their treatment and care.

Testicular Cancer Facts

Men have testicles, also called testes, which are part of their sexual or reproductive systems. The testicles are glands that produce testosterone, which is a hormone, and sperm. Immature sperm are created by germ cells in the testicles. Mature sperm cells fertilize female egg cells from the ovaries to begin a pregnancy.

Most testicular cancer forms in the germ cells. Testicular cancer occurs more often in young and middle-aged men, and it is the most frequently diagnosed cancer in men 20 to 35 years old. More than 8,800 new cases of the cancer are diagnosed in the United States each year.

(Source: National Cancer Institute)

Testicular Anatomy

Types of Testicular Cancer

There are two types of testicular germ cell cancers (with several sub-types), and they are based on the type of cell in which they are found. The frequency with which both occur is nearly equal. Specially trained OSUCCC – James pathology experts analyze samples of testicular tumor cells to classify them. Types include:


Seminomas grow more slowly and have a cure rate of more than 90 percent. They can be further classified into:

  • Classical
  • Spermatocytic


This type has a cure rate of nearly 100 percent. Major types include:

  • Yolk sac carcinoma
  • Choriocarcinoma
  • Teratoma
  • Embryonal carcinoma

In addition, cancer can spread to the testicles from another cancer in the body. When this happens, it's usually from a lymphoma, childhood leukemia, melanoma, or cancer in a man’s prostate, kidney or lung are responsible for these secondary testicular cancers.

Testicular Cancer Symptoms

Sometimes, testicular cancer may not cause any symptoms. When symptoms do occur, they may include the following:

  • A painless lump or swelling in either testicle
  • A change in how the testicle feels
  • A dull ache in the lower abdomen or the groin
  • A sudden buildup of fluid in the scrotum
  • Pain or discomfort in a testicle or in the scrotum

(Source: National Cancer Institute)

Having these symptoms does not necessarily mean you have testicular cancer. These symptoms could be caused by other conditions that affect men.

But if you have symptoms, you should tell your doctor, especially if symptoms have continued for longer than a few weeks.

If you’ve been diagnosed with testicular cancer, would like a second opinion or would like to speak with a testicular cancer specialist, please call The James Line at 800-293-5066 or 614-293-5066 to make an appointment.

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The James Cancer Hospital and Solove Research Institute

460 West 10th Avenue

Columbus, Ohio 43210

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