The internationally recognized specialists at the OSUCCC – James are transforming the way cancers are prevented, detected, treated and, yes, cured. Today, cancer is no longer solely defined by location or even by stage. We know there is no routine cancer, and when it comes to treating cancer, cellular therapy is the next frontier – and available right now at The James.

The Cellular Therapy Program experts at the OSUCCC – James treat patients who have acute lymphoblastic leukemia, diffuse large B-cell lymphoma, primary mediastinal B-cell lymphoma and aggressive follicular lymphoma using FDA-approved CAR-T therapies that revolutionize individualized care – and changing the way cancer is cured worldwide.

Our experts believe the best way to treat patients and manage their disease successfully is to deliver the latest, most effective treatments available. Because these specialists understand that cancer is complex, they use the most effective means of care to design the very best treatment plan – targeting each patient’s specific cancer – and offering improved outcomes, faster responses and fewer side effects.

By using cellular therapy, James specialists are able to harness a patient’s immune system, expanding it and unleashing it to fight back against cancer. Through innovative therapies such as CAR T-cell therapy and others, these therapies are now sometimes serving as a first-line treatment in many cases – often offering an effective, less harsh treatment plan than chemotherapy or radiation therapy.

If you’ve been diagnosed with cancer, would like a second opinion or would like to speak with a cancer specialist about cellular therapy options, please call The James Line at 800-293-5066 or 614-293-5066 to make an appointment. Specialized cell therapy coordinators are also available to answer questions at 614-688-7868.

Transforming Individualized Treatment

CAR-T therapy is a type of cellular therapy – a new, proven, leading-edge approach to immunotherapy available right here at the OSUCCC – James.

Called CAR-T for short, this living-drug therapy involves using a patient’s own white blood cells. Specially trained James experts remove white blood cells (called T cells) from the patient’s blood, then in the lab, place what’s called a Chimeric Antigen Receptor (or CAR) on the cells’ surface to retrain them to identify a specific cancer-signal on that surface.

The specialists then infuse these CAR T-cells back into the patient, where these modified cancer-fighters then target and attack only the cancerous cells.

As one of the highest volume cellular therapy sites in the United States, our teams of cancer specialists and subspecialists administer CAR T-cells safely and effectively.

And as an early site for CAR-T research trials, the OSUCCC – James continues to enroll patients in CAR-T clinical studies.


The OSUCCC – James Cellular Therapy Program is accredited by the Foundation for the Accreditation of Cellular Therapy (FACT). This leading regulatory institution governs many hospitals and organizations involved in hematology, blood and marrow transplant, blood banks and cellular therapy.

As part of this accreditation, the Cellular Therapy Program is required to report quality metrics to the Center for International Blood and Marrow Transplant Research, the U.S. Food and Drug Administration (FDA), and other groups.

Referrals and Appointments

The OSUCCC – James medical experts include world-renowned cancer specialists, subspecialists and super subspecialists in cancer prevention, detection, diagnosis and treatment.

To make an appointment (or as a provider, refer a patient), please call The James Line at 614-293-5066 or 800-293-5066. The James Line is a free, confidential telephone service staffed by nurses to provide callers with cancer information and physician referrals.

Specialized cell therapy coordinators are also available to answer questions at 614-688-7868.

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