Anne M Noonan, MBBCh
Physician
Gender: female
Languages: Gaelic
Research Program: Translational Therapeutics
About Me
More info forI am a medical oncologist who specializes in the treatment of breast cancer and gastrointestinal malignancies like esophageal, pancreatic and colorectal cancers, as well as hepatocellular carcinoma. My medical degree, residency and initial fellowship in medical oncology were completed in Ireland followed by a second fellowship in medical oncology at the National Cancer Institute in Bethesda, Maryland, where I focused on laboratory research and biomarker-driven phase I and II clinical trials. I currently serve as an assistant professor in the Department of Internal Medicine at The Ohio State University and as section chief of the Gastrointestinal Medical Oncology Section. As a member of the Translational Therapeutics Program at the OSUCCC – James, my research interests include the development of biomarker-driven targeted therapies through clinical trials and translational research. In 2012, I received the Marsha Rivkin Scientific Scholar Award for my work on proteomic biomarker development to treat relapsed ovarian cancer. I have also been published in the Journal of the National Cancer Institute, Cancer Research, Clinical Cancer Research and the British Medical Journal. I'm committed to providing individualized, multidisciplinary care for my patients by incorporating supportive treatments as well as the most up-to-date cancer therapies, including clinical trials. At the OSUCCC – James, we have the unique opportunity to access opinions from different cancer specialists and use the latest therapies to provide specific cancer care for each patient. Our collegial environment, cutting-edge science and united mission to end cancer make coming to work a privilege and an honor.
Clinical Expertise
More info for- Stomach Cancers
- Liver Cancers
- Pancreatic Cancers
- Referral and Consultation
- Experimental Liver Cancers
- Gastrointestinal Cancers
- Colorectal Cancers
- Cancers
- Drug Discovery
- Esophageal Cancers
Research Interests
More info for- Lymphoma, T-Cell, Peripheral
- Neoplasms
- Neutropenia
- Breast Neoplasms
- Depression
- Lymphoma, T-Cell, Cutaneous
- Hypersensitivity
- Neoplasm Metastasis
- Heart Rate
- Ovarian Neoplasms
Where I See Patients
More info forEducation & Training
More info forPh.D.
- National University of Ireland
2 Earlsfort TER, Dublin
MB /BCH.
- Cork University School of Medicine
Brookfield Health Sciences Complex, Cork
undefined - Internal Medicine
- Cork University School of Medicine
Brookfield Health Sciences Complex, Cork
undefined - Medical Oncology
- Cork University School of Medicine
Brookfield Health Sciences Complex, Cork
undefined - Medical Oncology
- Beaumont Hospital
PO Box 1297, Dublin 9
undefined - Medical Oncology
- Royal College of Surgeons-Ireland
123 St Stephen's Green, Dublin 2
- National University of Ireland
Academic Office & Contact Information
More info forEmail:
noonan.71@osu.eduReviews
More info forPatient Satisfaction Review
The overall patient satisfaction rating is an average of all patient responses to the five questions gathered from the Outpatient Oncology survey, developed by Press Ganey Associates for use in oncology clinics across the country. On behalf of The James, Press Ganey administers the survey to patients who see our providers in an outpatient clinic office. For additional information about the patient satisfaction survey, please visit our
Patient Satisfaction Survey page The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of The James.
Videos
More info forPublications
More info forJune 23, 2021A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186.
Herting CJ, Farren MR, Tong Y, Liu Z, O'Neil B, Bekaii-Saab T, Noonan A, McQuinn C, Mace TA, Shaib W, Wu C, El-Rayes BF, Shahda S, Lesinski GB
Cancer Immunol Immunother
June 2, 2021Randomized Phase II Study of PET Response-Adapted Combined Modality Therapy for Esophageal Cancer: Mature Results of the CALGB 80803 (Alliance) Trial.
Goodman KA, Ou FS, Hall NC, Bekaii-Saab T, Fruth B, Twohy E, Meyers MO, Boffa DJ, Mitchell K, Frankel WL, Niedzwiecki D, Noonan A, Janjigian YY, Thurmes PJ, Venook AP, Meyerhardt JA, O'Reilly EM, Ilson DH
J Clin Oncol
February 1, 2021Patient-reported sexual function of breast cancer survivors with genitourinary syndrome of menopause after fractional CO2 laser therapy.
Quick AM, Zvinovski F, Hudson C, Hundley A, Evans C, Stephens JA, Arthur E, Ramaswamy B, Reinbolt RE, Noonan AM, VanDeusen JB, Wesolowski R, Stover DG, Williams NO, Sardesai SD, Faubion SS, Loprinzi CL, Lustberg MB
Menopause
December 19, 2020From Hospice to Hope: Colloid Carcinoma of the Pancreas.
Zeh R, Beal EW, Noonan A, Cloyd JM
Am Surg
December 15, 2020Matrix Drug Screen Identifies Synergistic Drug Combinations to Augment SMAC Mimetic Activity in Ovarian Cancer.
Noonan AM, Cousins A, Anderson D, Zeligs KP, Bunch K, Hernandez L, Shibuya Y, Goldlust IS, Guha R, Ferrer M, Thomas CJ, Annunziata CM
Cancers (Basel)
December 1, 2020Liver Cancer-Specific Serine Protease Inhibitor Kazal Is a Potentially Novel Biomarker for the Early Detection of Hepatocellular Carcinoma.
Lu F, Shah PA, Rao A, Gifford-Hollingsworth C, Chen A, Trey G, Soryal M, Talat A, Aslam A, Nasir B, Choudhry S, Ishtiaq R, Sanoff H, Conteh LF, Noonan A, Hu KQ, Schmidt C, Fu M, Civan J, Xiao G, Lau DT, Lu X
Clin Transl Gastroenterol
November 1, 2020Worry and rumination in breast cancer patients: perseveration worsens self-rated health.
Renna ME, Rosie Shrout M, Madison AA, Lustberg M, Povoski SP, Agnese DM, Reinbolt RE, Wesolowski R, Williams NO, Ramaswamy B, Sardesai SD, Noonan AM, VanDeusen JB, Malarkey WB, Kiecolt-Glaser JK
J Behav Med
August 27, 2020Post-diagnosis dietary insulinemic potential and survival outcomes among colorectal cancer patients.
Tabung FK, Noonan A, Lee DH, Song M, Clinton SK, Spakowicz D, Wu K, Cheng E, Meyerhardt JA, Fuchs CS, Giovannucci EL
BMC Cancer
July 6, 2020Implementing a multidisciplinary approach for older adults with Cancer: geriatric oncology in practice.
Presley CJ, Krok-Schoen JL, Wall SA, Noonan AM, Jones DC, Folefac E, Williams N, Overcash J, Rosko AE
BMC Geriatr
July 1, 2020Features, Outcomes, and Management Strategies of Male Breast Cancer: A Single Institution Comparison to Well-Matched Female Controls.
Liu J, Suresh A, Palettas M, Stephens J, Ganju A, Morgan E, Kassem M, Hou Y, Parwani A, Noonan A, Reinbolt R, VanDeusen J, Sardesai S, Williams N, Cherian M, Tozbikian G, Stover DG, Lustberg M, Li Z, Ramaswamy B, Wesolowski R
Abstr Euro J of Hum Gen
June 2, 2020Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice.
Huang KM, Leblanc AF, Uddin ME, Kim JY, Chen M, Eisenmann ED, Gibson A, Li Y, Hong KW, DiGiacomo D, Xia SH, Alberti P, Chiorazzi A, Housley SN, Cope TC, Sprowl JA, Wang J, Loprinzi CL, Noonan A, Lustberg M, Cavaletti G, Pabla N, Hu S, Sparreboom A
J Clin Invest
June 1, 2020CD200 promotes immunosuppression in the pancreatic tumor microenvironment.
Choueiry F, Torok M, Shakya R, Agrawal K, Deems A, Benner B, Hinton A, Shaffer J, Blaser BW, Noonan AM, Williams TM, Dillhoff M, Conwell DL, Hart PA, Cruz-Monserrate Z, Bai XF, Carson Iii WE, Mace TA
J Immunother Cancer
May 16, 2020Neoadjuvant-modified FOLFIRINOX vs nab-paclitaxel plus gemcitabine for borderline resectable or locally advanced pancreatic cancer patients who achieved surgical resection.
Wolfe AR, Prabhakar D, Yildiz VO, Cloyd JM, Dillhoff M, Abushahin L, Alexandra Diaz D, Miller ED, Chen W, Frankel WL, Noonan A, Williams TM
Cancer Med
May 6, 2020Metastatic breast cancer patient perceptions of somatic tumor genomic testing.
Adams EJ, Asad S, Reinbolt R, Collier KA, Abdel-Rasoul M, Gillespie S, Chen JL, Cherian MA, Noonan AM, Sardesai S, VanDeusen J, Wesolowski R, Williams N, Shapiro CL, Macrae ER, Pilarski R, Toland AE, Senter L, Ramaswamy B, Lee CN, Lustberg MB, Stover DG
BMC Cancer
April 27, 2020Primary care physician's confidence and coordination regarding the survivorship care for older breast cancer survivors.
Stephens C, Klemanski D, Lustberg MB, Noonan AM, Brill S, Krok-Schoen JL
Support Care Cancer
April 27, 2020Immune checkpoint inhibitors in hepatocellular cancer: current understanding on mechanisms of resistance and biomarkers of response to treatment.
Onuma AE, Zhang H, Huang H, Williams TM, Noonan A, Tsung A
Gene Expr
February 13, 2020Pathologic complete response following neoadjuvant therapy for pancreatic ductal adenocarcinoma: defining the incidence, predictors, and outcomes.
Cloyd JM, Ejaz A, Shen C, Dillhoff M, Williams TM, Noonan A, Pawlik TM, Tsung A
HPB (Oxford)
January 1, 2020Perspectives of Survivorship Care Plans Among Older Breast Cancer Survivors: A Pilot Study.
Krok-Schoen JL, Naughton MJ, Noonan AM, Pisegna J, DeSalvo J, Lustberg MB
Cancer Control
December 6, 2019Fractional CO2 laser therapy for genitourinary syndrome of menopause for breast cancer survivors.
Quick AM, Zvinovski F, Hudson C, Hundley A, Evans C, Suresh A, Stephens JA, Arthur E, Ramaswamy B, Reinbolt RE, Noonan AM, VanDeusen JB, Wesolowski R, Stover DG, Williams NO, Sardesai SD, Smith KL, Faubion SS, Loprinzi CL, Lustberg MB
Support Care Cancer
November 1, 2019Hepatocellular carcinoma: an update on investigational drugs in phase I and II clinical trials.
Noonan A, Pawlik TM
Expert Opin Investig Drugs
October 3, 2019Ibrutinib potentiates anti-hepatocarcinogenic efficacy of sorafenib by targeting EGFR in tumor cells and BTK in immune cells in the stroma.
Lin CH, Elkholy KH, Wani NA, Li D, Hu P, Barajas JM, Yu L, Zhang X, Jacob ST, Khan WN, Bai XF, Noonan AM, Ghoshal K
Mol Cancer Ther
September 7, 2019Comparison of conventional versus liposomal irinotecan in combination with fluorouracil for advanced pancreatic cancer: a single-institution experience.
Tossey JC, Reardon J, VanDeusen JB, Noonan AM, Porter K, Arango MJ
Med Oncol
September 4, 2019Association of Liver-Directed Local Therapy With Overall Survival in Adults With Metastatic Intrahepatic Cholangiocarcinoma.
Sebastian NT, Tan Y, Miller ED, Williams TM, Noonan AM, Hays JL, Abdel-Misih S, Diaz DA
JAMA Netw Open
July 28, 2019Neoadjuvant and adjuvant treatment strategies for hepatocellular carcinoma.
Akateh C, Black SM, Conteh L, Miller ED, Noonan A, Elliott E, Pawlik TM, Tsung A, Cloyd JM
World J Gastroenterol
July 17, 2019Progression-Free Survival for Real-World Use of Palbociclib in Hormone Receptor-Positive Metastatic Breast Cancer.
Wilkie J, Schickli MA, Berger MJ, Lustberg M, Reinbolt R, Noonan A, Ramaswamy B, Sardesai S, VanDeusen J, Wesolowski R, Williams N, Stover DG, Li J, Vargo CA
Clin Breast Cancer
June 1, 2019Physical Activity After Breast Cancer Surgery: Does Depression Make Exercise Feel More Effortful than It Actually Is?
Padin AC, Wilson SJ, Bailey BE, Malarkey WB, Lustberg MB, Farrar WB, Povoski SP, Agnese DM, Reinbolt RE, Wesolowski R, Williams N, Sardesai S, Ramaswamy B, Noonan AM, Vandeusen JB, Haas GJ, Kiecolt-Glaser JK
Int J Behav Med
May 1, 2019ASCO gastrointestinal cancers symposium: Perspectives on older adults with gastrointestinal malignancies.
Arora SP, Noonan AM, Vanderwalde N, Williams GR
J Geriatr Oncol
March 24, 2019Evaluation of a locked nucleic acid form of antisense oligo targeting HIF-1α in advanced hepatocellular carcinoma.
Wu J, Contratto M, Shanbhogue KP, Manji GA, O'Neil BH, Noonan A, Tudor R, Lee R
World J Clin Oncol
January 1, 2019Significant and Durable Clinical Response to Sorafenib and Radiation Therapy for a Patient With Stage IV Hepatocellular Carcinoma and LRRK2 Mutation.
Yang L, Wald P, Roychowdhury S, Noonan AM, Zuo L, Chuang CC, Reeser J, Wuthrick E, Schmidt C, Williams T
JCO Precis Oncol
September 1, 2018Comprehensive Geriatric Assessment in Oncology: Best Practices in Caring for Older Patients.
Overcash J, Ford N, Erdeljac HP, Fugett S, Knauss B, Kress E, Utendorf C, Noonan A
J Adv Pract Oncol
January 1, 2018Factors Associated With Poor Sleep in Older Women Diagnosed With Breast Cancer
Overcash J, Tan A, Patel K, Noonan AM
Oncol Nurs Forum
Consulting and Related Relationships
More info forAt The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 09/30/2024, Dr. Noonan has reported relationships with the companies or entities listed below. If you have questions about the relationships listed below, please ask the faculty member. If you have questions about how these relationships are monitored by The Ohio State University Wexner Medical Center, please contact our Compliance Office.
- Eisai, Inc.
Patient Comments
Dr Noonan and staff are excellent. They review all details in great depth and address any issues or concerns coming up. I am so pleased to have her as my oncologist and I am doing well.
Good
Life savers. And very open about diagnosis, wishes, and coordination with care team.
Dr. Noonan has always treated me with respect and kindness. She goes in depth about how my cancer is affecting my body. She explains how the treatments work in great detail. She always asks me if I have any concerns or issues. She always addresses my concerns/issues until they are resolved. She has had her staff print out details of other documents that I might question. I feel very grateful that she is my cancer doctor. I would always choose her if I have to go through cancer again. She exhibits professionalism and deep compassion and empathy for others.
The care provider was the best I have ever experienced.
Excellent
Dr. Noonan always explains things thoroughly so that I understand. She makes sure appointments scheduled fit my schedule. If I was able to answer all these questions with a 10 for phenomenal I would.Claire Jackman, who is over my clinical trial is, keeps me well informed. She is an invaluable member of the team.
Dr Noonan provides excellent care & always answers all my concerns
Dr. Noonan was outstanding.
I love everyone there . They are so nice
Excellent
Good
2 hours late
Dr. Noonan seems to be over worked. More patients that time.
Dr. Noonan is knowledgeable and takes her time with patients; my ONLY concern is the wait time to see her is awful. If she could please manager her time better.
I have to constantly follow up with dr./nurses to see what is going on. I don't get contacted when dr./nurse has completed a test/Rx order placed etc.
Dr. Noonan was very insightful and answered our questions thoroughly.