Ashish Manne, MBBS
Academic Title: Assistant Professor in the College of Medicine
Research Program: Translational Therapeutics
About Me
More info forI am a medical oncologist who specializes in treating gastrointestinal malignancies, such as esophageal cancers, colorectal cancers and hepatopancreaticobiliary tract cancers, which include cancers of the pancreas, ampulla, liver and biliary tract. I believe in a precision approach to cancer care using the latest technology, like genetic testing of tissue and/or blood, as well as non-chemotherapy options if possible. Even in stage IV cancers, I try to be aggressive when needed if I think there is a chance to cure. I work with a multidisciplinary team of like-minded colleagues who are equally aggressive and take a patient-centric approach in order to deliver the best possible care. The OSUCCC – James offers a wide range of clinical trials for patients to enroll in that can be beneficial as well. In addition to my clinical duties, I am a member of the Translational Therapeutics Program, where my research focuses on the predictive and prognostic markers of hepatobiliary and pancreatic cancers, as well as exploring the role of the microbiome in the treatment response for these cancers. I am also interested in addressing clinicopathological risk factors that help predict immune-related adverse events and ways to overcome them. My current research projects focuses on new biomarkers in blood for managing pancreatic cancers. I am leading a clinical trial to treat biliary tract cancers (cholangiocarcinoma) with novel drugs and pancreatic cancer with electromagnetic fields. My work has been published in such peer-reviewed journals as Cancers, Frontiers in Oncology, and Frontiers in immunology, and as book chapters. The thing I enjoy most about working at the OSUCCC – James is that there are experts in every field who are always willing to collaborate. I also have the opportunity to engage in clinical and basic research to help in pushing the boundaries of cancer care and treatment, with the ultimate goal of creating a cancer-free world.
Clinical Expertise
More info for- Colon Cancers
- Liver Cancers
- Pancreatic Cancers
- Gastrointestinal Cancers
- Rectal Cancers
- Biliary Tract Cancers
- Colorectal Cancers
- Esophageal Cancers
Where I See Patients
More info forEducation & Training
More info forMedical School
- Osmania Medical College
Hyderabad 500 095, Andhra Pradesh, India
Residency - Internal Medicine
- University of Alabama Medical West
US Highway 11 South, Bessemer, AL
Fellowship - Blood Banking/Transfusion Medicine
- University of Alabama School of Medicine
619 19Th St S, Birmingham, AL
Fellowship - Medical Oncology
- University of South Alabama College of Medicine
2451 University Hospital Dr, Mobile, AL
- Osmania Medical College
Academic Office & Contact Information
More info forAcademic Office:
Lincoln Tower 1335
1800 Cannon Dr
Columbus, Ohio 43210Email:
ashish.manne@osumc.eduReviews
More info forPatient Satisfaction Review
The overall patient satisfaction rating is an average of all patient responses to the five questions gathered from the Outpatient Oncology survey, developed by Press Ganey Associates for use in oncology clinics across the country. On behalf of The James, Press Ganey administers the survey to patients who see our providers in an outpatient clinic office. For additional information about the patient satisfaction survey, please visit our
Patient Satisfaction Survey page The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of The James.
Publications
More info forAugust 20, 2024Mature MUC5AC Expression in Resected Pancreatic Ductal Adenocarcinoma Predicts Treatment Response and Outcomes.
Manne A, Esnakula A, Sheel A, Sara A, Manne U, Paluri RK, He K, Yang W, Sohal D, Kasi A, Noonan AM, Mittra A, Hays J, Roychowdhury S, Malalur P, Rahman S, Jin N, Cloyd JM, Tsai S, Ejaz A, Pitter K, Miller E, Thanikachalam K, Dillhoff M, Yu L
Int J Mol Sci
July 11, 2024Combination of dual JAK/HDAC inhibitor with regorafenib synergistically reduces tumor growth, metastasis, and regorafenib-induced toxicity in colorectal cancer.
Bajpai P, Agarwal S, Afaq F, Al Diffalha S, Chandrashekar DS, Kim HG, Shelton A, Miller CR, Singh SK, Singh R, Varambally S, Nagaraju GP, Manne A, Paluri R, Khushman M, Manne U
J Exp Clin Cancer Res
January 1, 2024Immune checkpoint inhibitor-induced subacute cutaneous lupus erythematosus: a case report and review of the literature.
Khorasanchi A, Korman AM, Manne A, Meara A
Front Med (Lausanne)
January 1, 2024Immune Checkpoint Inhibitor-Related Autoimmune Pancreatitis-Risk Factors and Outcomes.
Nuguru S, Manne A
Gastro Hep Adv
October 2, 2023Differential Expression and Diagnostic Value of MUC5AC Glycoforms in Pancreatic Ductal Adenocarcinoma.
Manne A, Yu L, Hart PA, Tsung A, Esnakula A
Cancers (Basel)
September 18, 2023Is Cell-Free DNA Testing in Hepatocellular Carcinoma Ready for Prime Time?
Jeepalyam S, Sheel A, Ejaz A, Miller E, Manne A
Int J Mol Sci
April 30, 2023Predictive Value of MUC5AC Signature in Pancreatic Ductal Adenocarcinoma: A Hypothesis Based on Preclinical Evidence.
Manne A, Kasi A, Esnakula AK, Paluri RK
Int J Mol Sci
March 30, 2023Management of locally advanced intrahepatic cholangiocarcinoma: a narrative review.
Bressler L, Bath N, Manne A, Miller E, Cloyd JM
Chin Clin Oncol
January 1, 2023Combined radiotherapy and immune checkpoint inhibition for the treatment of advanced hepatocellular carcinoma.
Shannon AH, Manne A, Diaz Pardo DA, Pawlik TM
Front Oncol
January 1, 2023The adherence to the American Association for the Study of Liver Diseases 2018 guidelines in the management of hepatocellular carcinoma and its impact on survival.
Manne A, Mulekar M, Escobar D, Prodduturvar P, Fahmawi Y, Henderson P, Abdul-Rahim O, Hussain Z, Liles S, Fonseca A, Howard JH, Mneimneh W, Gilbert R, Alkharabsheh O, Pai S, White ZB, Nelson C, Khushman M
J Cancer Res Ther
December 22, 2022Stereotactic Body Radiation Therapy (SBRT) Plus Immune Checkpoint Inhibitors (ICI) in Hepatocellular Carcinoma and Cholangiocarcinoma.
Jiang J, Diaz DA, Nuguru SP, Mittra A, Manne A
Cancers (Basel)
July 15, 2022Is Cell-Free DNA Testing in Pancreatic Ductal Adenocarcinoma Ready for Prime Time?
Sheel A, Addison S, Nuguru SP, Manne A
Cancers (Basel)
April 25, 2022Changing Landscape of Systemic Therapy in Biliary Tract Cancer.
Woods E, Le D, Jakka BK, Manne A
Cancers (Basel)
January 1, 2022Risk Factors and Biomarkers for Immune-Related Adverse Events: A Practical Guide to Identifying High-Risk Patients and Rechallenging Immune Checkpoint Inhibitors.
Chennamadhavuni A, Abushahin L, Jin N, Presley CJ, Manne A
Front Immunol
June 19, 2021Understanding the Clinical Impact of MUC5AC Expression on Pancreatic Ductal Adenocarcinoma.
Manne A, Esnakula A, Abushahin L, Tsung A
Cancers (Basel)
May 1, 2021Clinical and Hematological Predictors of High-Grade Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitors.
Manne A, Mulekar MS, Escobar DE, Alsayed A, Sharma G, Prodduturvar P, Khushman M, Howard JH, Gilbert R, Alkharabsheh O
J Clin Med Res
January 1, 2021Biliary Tract Cancers: Treatment Updates and Future Directions in the Era of Precision Medicine and Immuno-Oncology.
Manne A, Woods E, Tsung A, Mittra A
Front Oncol
Consulting and Related Relationships
More info forAt The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 09/30/2024, Dr. Manne has reported relationships with the companies or entities listed below. If you have questions about the relationships listed below, please ask the faculty member. If you have questions about how these relationships are monitored by The Ohio State University Wexner Medical Center, please contact our Compliance Office.
- AstraZeneca
- Pfizer
Patient Comments
Dr. Manne and his NP were thorough and knowledgeable
This provider was very blunt and almost negative in plans for my treatment. He brought my wife to tears and in a near panic state.
Nurse practitioner was very informative and caring
Great staff.
It was a great experience, friendly and glad to have the service
Dr. Manne was quite thorough.
No bad experiences.
Dr. Ejaz & Dr. Manne are great!