David O'Malley, MDThe James Cancer Center
A physician, or doctor, is extensively trained to diagnose and treat complex medical problems. Often, physicians focus their practice on certain disease categories, treatment methods or patient types. Physicians can diagnose and treat illness, prescribe medication, offer medical consultation and advice, perform surgery and more.
- Gynecologic Oncology
- Ovarian Cancers
- Soft Tissue Cancers
- Endometrial Cancers
- Gynecologic Cancers
- Minimally Invasive Surgical Procedures
- Peritoneal Cancers
- Cervical Cancer
- Reproductive Health
- Uterine Cancers
- Women's Health
- Vaginal Cancers
- Vulvar Cancers
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I am a professor and faculty member since 2005. I completed my gynecologic oncology fellowship at Yale University, residency at Case Western Reserve University (MetroHealth) and the Cleveland Clinic Foundation, medical school at Wayne State and earned my undergraduate degree at the University of Notre Dame. I am the director for clinical research in gynecologic oncology, as well as the co-director of the gynecologic oncology phase I program, and I also serve as the ORIEN physician liaison for the Ohio State University Comprehensive Cancer Center. I am active nationally as a committee member for the NCI Gynecologic Cancer Steering Committee’s Ovarian Task Force, NRG Oncology (Ovarian Cancer and Developmental Therapeutics Groups), Society of Gynecologist Oncology and the American Society of Clinical Oncology. My passion for improving the care of patients with gynecologic cancers and expertise in ovarian cancer resulted in my appointment to the panel of the National Comprehensive Cancer Network (NCCN) Guidelines for Ovarian Cancer, where I continue as an active participant.
My drive to have no patient with a gynecologic cancer succumb to their disease guides my research that specializes in the development of therapeutics/treatments for gynecologic cancers, concentrating on ovarian and uterine (endometrial). I have designed, coordinated and published on all levels of clinical trials to include phase I, II and III studies with a special interest in novel compounds. I continue to work to improve not only the therapies (novel techniques/targets/immune therapy) but to identify patients who would benefit (or not benefit) from different treatment options in ovarian and uterine cancer (specifically high-risk histologies) while minimizing side effects.
The quest to improve patient outcomes has led me to my work on improving surgical techniques. Robotic-assisted, minimally invasive surgical techniques have been implemented in all aspects of practice, resulting in the publication of the improved outcomes and as an instructor on these techniques at a national level.
I am honored and humbled to help care for the amazing women who are my patients and their families. Improving the care of women with gynecologic cancer through research has led to me being recognized with over 100 publications in the most respected journals, including New England Journal of Medicine, Journal of Clinical Oncology, Lancet Oncology, JAMA Oncology and Nature Genetics. My compassionate nature and communication has been recognized with patient satisfaction that ranks at the very top for the country. My accomplishments have also resulted in being named as one of the Best/Top Doctors in America by US News and World Report (Castle Connelly) and Best Doctors for multiple years. However, my greatest pride comes from my family and my beautiful wife and our five amazing children.
Education and Background
Case Western Reserve University
OB/GYN / Gynecological Oncology
Yale University School of Medicine
New Haven, CT
- American Board of OB/GYN
- American Board of OB/GYN (Subspecialty: Gynecologic Oncology)
- Department of Obstetrics & Gynecology
- Division of Gynecologic Oncology
I see patients at
Stefanie Spielman Comprehensive Breast Center
1145 Olentangy River Road, Columbus, Ohio 43212
JamesCare Gynecologic Oncology at Mill Run
3651 Ridge Mill Drive, Hilliard, Ohio 43026
Consulting and Related Relationships
At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 12/20/2018, Dr. O'Malley has reported relationships with the companies or entities listed below. If you have questions about the relationships listed below, please ask the faculty member. If you have questions about how these relationships are monitored by The Ohio State University Wexner Medical Center, please contact our Compliance Office.
- Clovis Oncology
- Tesaro, Inc.
- Regeneron Pharmaceuticals
- Janssen Research
- AbbVie Inc.
- Ambry Genetics
- Immunogen, Inc.
- Myriad Genetic Laboratories, Inc.