Gregory Otterson, MD

The James Cancer Center
Gregory Otterson

A physician, or doctor, is extensively trained to diagnose and treat complex medical problems. Often, physicians focus their practice on certain disease categories, treatment methods or patient types. Physicians can diagnose and treat illness, prescribe medication, offer medical consultation and advice, perform surgery and more.


  • Medical Oncology

Clinical Expertise

  • Lung Cancers
  • Lung Cancers
  • Pleural Cancers
  • Thymus Cancers
Insurance Information



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I’m a thoracic oncologist dedicated to advancing the care and treatment of patients with thoracic malignancies – such as adenocarcinoma, mesothelioma and thymic cancers – by helping develop novel therapeutic approaches to these diseases. Such treatments range from combinations of conventional cytotoxic chemotherapy, novel targeted agents and immunotherapy applied to patients with early stage or advanced disease. I was named to the Castle Connolly list of “Regional Top Doctors” from 2006-2018 and rated in the top 10 percent of physicians in the nation for patient satisfaction in 2017.

I am a professor of internal medicine, associate division director for education in the Division of Medical Oncology, associate program director of the Hematology/Oncology Fellowship Program and clinical director of the Thoracic Oncology Disease Specific Research Group at OSUCCC – James. I serve on the National Comprehensive Cancer Network (NCCN) nonsmall cell lung cancer guidelines panel.

At The James, we have a true multi-disciplinary team in thoracic oncology that includes medical oncologists, thoracic surgeons, radiation oncologists, pulmonologists, pathologists, radiologists, nurses, pharmacists, nurse practitioners and physician assistants. Together we work to continually improve patients’ quality of life and develop effective therapies in an effort to end cancer.

Education and Background


  • Georgetown University School of Medicine

    Washington, DC


  • Rush-Presbyterian-St.Luke's Med Ctr

    Chicago, IL


  • Medical Oncology

    National Cancer Institute

    Bethesda, MD

Board Certifications

  • American Board of Internal Medicine
  • American Board of Internal Medicine (Subspecialty: Medicine Oncology)

Academic Department

I see patients at

The James at Brain and Spine Hospital

300 West 10th Avenue, Columbus, Ohio 43210


Consulting and Related Relationships

At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 12/20/2018, Dr. Otterson has reported no relationships with companies or entities.


Clinical Trials | Lead

  • RTOG-1008



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