Jacob M Kaufman, MD, PHD

Jacob M Kaufman, MD, PHD

Physician

4.8 out of 5

Specialty:Medical Oncology

Gender: Male

Academic Title: Assistant Professor in the College of Medicine

Research Program: Translational Therapeutics

  • About Me

    I am a medical oncologist who specializes in treating patients with lung cancer. I want to provide care that is as individualized as possible. That means understanding as much as we can about the biology of the patient's cancer, as well as the goals and priorities of each patient, and then using this to select the best possible approach to treatment. The multidisciplinary treatment teams at The James work together to select, plan and carry out those treatments, and to support patients through this process on many levels. As a member of the Translational Therapeutics Program at the OSUCCC – James, my research is focused on understanding how the specific genetic background of each cancer affects their behaviors in patients, such as immune system evasion and response to treatments. My laboratory specifically focuses on the effects of mutations in the LKB1 gene (also known as STK11). Tumors with these mutations are difficult to treat because they do not respond to our best targeted drugs, such as EGFR and ALK inhibitors, and are also resistant to our best immunotherapy treatments. I hope to use a better understanding of these processes to develop novel and improved treatments that are guided by precise knowledge of the tumor biology. This is an incredible time to be involved in cancer research. Dozens of precision treatments have been developed in lung cancer over the past 20 years that have completely changed our approach to treating patients, and as a result, patient outcomes and survival continue to improve year after year. I am passionate about being part of the discovery process that fuels these advances in patient care and collaborating with fellow researchers to achieve our goal of a cancer-free world. At the OSUCCC – James, specialists from across all fields are available and eager to work together on projects to advance our understanding of cancer and improve patient care and outcomes. In particular, the Pelotonia Institute for Immuno-Oncology (PIIO) provides a focal point for integrating researchers who study better ways to harness the immune system to target cancer. The PIIO is made possible by an incredible level of community engagement and fundraising through Pelotonia, which brings together the greater Columbus and Ohio areas in support of cancer research. This level of community support is so special and is really unique to this institution. In addition to my clinical and research work, I serve as an assistant professor in the Division of Medical Oncology at The Ohio State University. I have also been published in numerous scientific journals, including JAMA, Cancer Research and Journal of Thoracic Oncology.

  • Clinical Expertise

    • Lung Cancers
    • Medical Oncology
  • Where I See Patients

    Ohio State Brain and Spine Hospital

    Ohio State Brain and Spine Hospital

    Location Information
  • Education & Training

    Fellowship - Hematology & Oncology

    • Duke University Medical Center
      Box 3808, Durham, NC

    Residency - Internal Medicine

    • Duke University Medical Center
      Box 3808, Durham, NC

    Medical School

    • Vanderbilt University School of Medicine
      203 Light Hall, Nashville, TN
  • Academic Office & Contact Information

    Academic Office:

    Biomedical Research Tower
    460 W 12th Ave
    Columbus, Ohio 43210-2210

  • Reviews

    Patient Satisfaction Review

    The overall patient satisfaction rating is an average of all patient responses to the five questions gathered from the Outpatient Oncology survey, developed by Press Ganey Associates for use in oncology clinics across the country. On behalf of The James, Press Ganey administers the survey to patients who see our providers in an outpatient clinic office. For additional information about the patient satisfaction survey, please visit our Patient Satisfaction Survey page

    The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of The James.

    4.8 out of 5 overall

    Kept you informed about your condition and treatment
    4.8 / 5
    Amount of time spent with you
    4.7 / 5
    Concern for your questions and issues
    4.8 / 5
    Skill and knowledge
    4.8 / 5
    Overall quality of care
    4.8 / 5

    Patient Comments

    Reviewed on September 11, 2024

    Again, Dr. Kaufman is an exceptional doctor.

    Reviewed on September 9, 2024

    Dr. Kaufman explained everything in great detail. He was patient and answered all of our questions and I felt he is very patient centered

    Reviewed on June 24, 2024

    Dr Kaufman was very friendly, professional, easy to talk to, and he had no problem answering any questions we asked. By the time we were done, we felt like we could trust him and agreed to his recomendations. Both my husband and I attended this meeting with him.

    Reviewed on May 6, 2024

    If the care providers are running a bit late that means, to me, that they're doing a thorough job.... It was never over-the top... Within reasonable limits and I was always informed

    Reviewed on April 29, 2024

    We felt like the only patient to be seen

    Reviewed on February 22, 2024

    Very comfortable.

    Reviewed on July 28, 2023

    Answered all questions & listened to concerns.

    Reviewed on July 19, 2023

    Dr. Kaufmann & Sarah NP. BEST EVER!!

    Reviewed on July 8, 2023

    Dr Kaufman is a good listener, exceptionally intelligent and conscientious, very kind and did not rush me despite my extensive questions. At this point he has my complete Trust.

  • Publications

    April 5, 2024

    CLO24-061: Overall Survival (OS) Impact for NSCLC Patients With irAE and Non-irAE Hospital Admissions During First-Line Pembrolizumab Treatment.

    Khorasanchi A, Zhao S, Wei L, Li M, Ho K, Abu-Sbeih H, Goodyear E, Secor A, Shields P, He K, Kaufman J, Memmott R, Alahmadi A, Carbone D, Otterson G, Meara A, Presley C, Owen D

    J Natl Compr Canc Netw

    November 1, 2023

    Association Between Pretreatment Chest Imaging and Immune Checkpoint Inhibitor Pneumonitis Among Patients With Lung Cancer.

    Wong A, Riley M, Zhao S, Zimmer J, Viveiros M, Wang JG, Esguerra V, Li M, Lopez G, Kendra K, Carbone DP, He K, Alahmadi A, Kaufman J, Memmott RM, Shields PG, Brownstein J, Haglund K, Welliver M, Otterson GA, Presley CJ, Wei L, Owen DH, Ho K

    J Natl Compr Canc Netw

  • Consulting and Related Relationships

    At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 09/30/2024, Dr. Kaufman has reported no relationships with companies or entities.