Jacob M Kaufman, MD, PHD
Academic Title: Assistant Professor in the College of Medicine
Research Program: Translational Therapeutics
About Me
More info forI am a medical oncologist who specializes in treating patients with lung cancer. I want to provide care that is as individualized as possible. That means understanding as much as we can about the biology of the patient's cancer, as well as the goals and priorities of each patient, and then using this to select the best possible approach to treatment. The multidisciplinary treatment teams at The James work together to select, plan and carry out those treatments, and to support patients through this process on many levels. As a member of the Translational Therapeutics Program at the OSUCCC – James, my research is focused on understanding how the specific genetic background of each cancer affects their behaviors in patients, such as immune system evasion and response to treatments. My laboratory specifically focuses on the effects of mutations in the LKB1 gene (also known as STK11). Tumors with these mutations are difficult to treat because they do not respond to our best targeted drugs, such as EGFR and ALK inhibitors, and are also resistant to our best immunotherapy treatments. I hope to use a better understanding of these processes to develop novel and improved treatments that are guided by precise knowledge of the tumor biology. This is an incredible time to be involved in cancer research. Dozens of precision treatments have been developed in lung cancer over the past 20 years that have completely changed our approach to treating patients, and as a result, patient outcomes and survival continue to improve year after year. I am passionate about being part of the discovery process that fuels these advances in patient care and collaborating with fellow researchers to achieve our goal of a cancer-free world. At the OSUCCC – James, specialists from across all fields are available and eager to work together on projects to advance our understanding of cancer and improve patient care and outcomes. In particular, the Pelotonia Institute for Immuno-Oncology (PIIO) provides a focal point for integrating researchers who study better ways to harness the immune system to target cancer. The PIIO is made possible by an incredible level of community engagement and fundraising through Pelotonia, which brings together the greater Columbus and Ohio areas in support of cancer research. This level of community support is so special and is really unique to this institution. In addition to my clinical and research work, I serve as an assistant professor in the Division of Medical Oncology at The Ohio State University. I have also been published in numerous scientific journals, including JAMA, Cancer Research and Journal of Thoracic Oncology.
Clinical Expertise
More info for- Lung Cancers
- Medical Oncology
Where I See Patients
More info forEducation & Training
More info forFellowship - Hematology & Oncology
- Duke University Medical Center
Box 3808, Durham, NC
Residency - Internal Medicine
- Duke University Medical Center
Box 3808, Durham, NC
Medical School
- Vanderbilt University School of Medicine
203 Light Hall, Nashville, TN
- Duke University Medical Center
Academic Office & Contact Information
More info forAcademic Office:
Biomedical Research Tower
460 W 12th Ave
Columbus, Ohio 43210-2210Email:
jacob.kaufman@osumc.eduReviews
More info forPatient Satisfaction Review
The overall patient satisfaction rating is an average of all patient responses to the five questions gathered from the Outpatient Oncology survey, developed by Press Ganey Associates for use in oncology clinics across the country. On behalf of The James, Press Ganey administers the survey to patients who see our providers in an outpatient clinic office. For additional information about the patient satisfaction survey, please visit our
Patient Satisfaction Survey page The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of The James.
Publications
More info forApril 5, 2024CLO24-061: Overall Survival (OS) Impact for NSCLC Patients With irAE and Non-irAE Hospital Admissions During First-Line Pembrolizumab Treatment.
Khorasanchi A, Zhao S, Wei L, Li M, Ho K, Abu-Sbeih H, Goodyear E, Secor A, Shields P, He K, Kaufman J, Memmott R, Alahmadi A, Carbone D, Otterson G, Meara A, Presley C, Owen D
J Natl Compr Canc Netw
November 1, 2023Association Between Pretreatment Chest Imaging and Immune Checkpoint Inhibitor Pneumonitis Among Patients With Lung Cancer.
Wong A, Riley M, Zhao S, Zimmer J, Viveiros M, Wang JG, Esguerra V, Li M, Lopez G, Kendra K, Carbone DP, He K, Alahmadi A, Kaufman J, Memmott RM, Shields PG, Brownstein J, Haglund K, Welliver M, Otterson GA, Presley CJ, Wei L, Owen DH, Ho K
J Natl Compr Canc Netw
Consulting and Related Relationships
More info forAt The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 09/30/2024, Dr. Kaufman has reported no relationships with companies or entities.
Patient Comments
Again, Dr. Kaufman is an exceptional doctor.
Dr. Kaufman explained everything in great detail. He was patient and answered all of our questions and I felt he is very patient centered
Dr Kaufman was very friendly, professional, easy to talk to, and he had no problem answering any questions we asked. By the time we were done, we felt like we could trust him and agreed to his recomendations. Both my husband and I attended this meeting with him.
If the care providers are running a bit late that means, to me, that they're doing a thorough job.... It was never over-the top... Within reasonable limits and I was always informed
We felt like the only patient to be seen
Very comfortable.
Answered all questions & listened to concerns.
Dr. Kaufmann & Sarah NP. BEST EVER!!
Dr Kaufman is a good listener, exceptionally intelligent and conscientious, very kind and did not rush me despite my extensive questions. At this point he has my complete Trust.