James Rocco, MD, PhD

The James Cancer Center
James Rocco

A physician, or doctor, is extensively trained to diagnose and treat complex medical problems. Often, physicians focus their practice on certain disease categories, treatment methods or patient types. Physicians can diagnose and treat illness, prescribe medication, offer medical consultation and advice, perform surgery and more.


  • Otolaryngology

Clinical Expertise

  • Pharyngeal Cancers
  • Tongue Cancers
  • Lip Cancers
  • Minimally Invasive Surgical Procedures
  • Robotics
  • Parotid Cancers
  • Laryngeal Cancers
  • Maxillary Sinus Cancers
  • Head and Neck Cancer
  • Skull Base Tumors
  • Nose Cancers
  • Oropharyngeal Cancers
  • Carotid Body Tumor
  • Salivary Gland Cancers
  • Hypopharyngeal Cancers
  • Tonsillar Cancers
  • Ear Cancer
  • Paranasal Sinus Cancers
Insurance Information



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My focus is providing the very best care for our head and neck cancer patients. I do this by combining my 20 years’ experience as a surgeon with the expertise of colleagues who can provide radiation and medical therapies if needed and with those who provide support for patients as they recover from treatment. As a team, we work together with patients to find the treatments that have the best chance of curing their cancer while minimizing side effects.

I was excited to have the opportunity to come to OSUCCC – James in 2015 to serve as Director of the Head and Neck Oncologic Surgery Division and Head and Neck Service Line Director. I came from the Massachusetts Eye and Ear Infirmary and Massachusetts General Hospital Department of Surgery multi-disciplinary head and neck cancer clinic, where I worked for 14 years following my MD/PhD from Mount Sinai Medical School and my residency training at the Johns Hopkins Hospital in Baltimore. I was also named to the Castle Connolly list of “Regional Top Doctors” from 2011-2018.

In addition to my clinical work, I direct an active NIH-supported laboratory research group that looks for characteristics of tumors that can be used to predict how well patients will respond to different types of therapy. This research is aimed at making it easier to guide personalized treatment approaches.

Working at the OSUCCC – James is very inspiring. Everyone is committed to cutting-edge research methods and developing crucial relationships with our patients so we can provide exceptional individualized care. It’s very rewarding to see the results of our work in our patients’ lives.

Education and Background


  • Mount Sinai School of Medicine

    New York, NY


  • Johns Hopkins Hospital

    Baltimore, MD

Board Certifications

  • American Board of Otolaryngology

Academic Department

I see patients at

The James Cancer Hospital and Solove Research Institute

460 West 10th Avenue, Columbus, Ohio 43210


Consulting and Related Relationships

At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 12/20/2018, Dr. Rocco has reported no relationships with companies or entities.


Clinical Trials | Lead


  • OSU-17128

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