John Phay, MD

The James Cancer Center
John Phay

A physician, or doctor, is extensively trained to diagnose and treat complex medical problems. Often, physicians focus their practice on certain disease categories, treatment methods or patient types. Physicians can diagnose and treat illness, prescribe medication, offer medical consultation and advice, perform surgery and more.


  • Surgical Oncology

Clinical Expertise

  • Adrenal Gland Cancers
  • Neuroendocrine Tumors
  • Endocrine Cancers
  • Parathyroid Diseases
  • Pituitary Cancers
  • Carcinoma, Neuroendocrine
  • Carcinoid Tumor
  • Adrenocortical Adenoma
  • Adrenocortical Carcinoma
  • Thyroid Cancer
  • Parathyroid Cancers
  • Gastrointestinal Cancers
  • Robotics
  • Minimally Invasive Surgical Procedures
Insurance Information



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I’m an endocrine surgeon, focusing on three endocrine glands: the thyroid, parathyroid and adrenal glands. I also serve as associate professor for the Ohio State University College of Medicine. In my career, I have performed more than 3,000 neck surgeries and 100+ robotic adrenalectomies. I was rated in the top 10 percent of physicians in the nation for patient satisfaction in 2016 and 2017.

In addition to a busy clinical practice, I have a research lab focused on thyroid cancer with two ongoing research projects. The first is examining a novel AMPK activator for the treatment of thyroid cancer. I’m currently studying the mechanism of action to potentially use synergistically with known BRAF inhibitors. My second research project is creating a molecular imaging agent for medullary thyroid cancer (MTC) and parathyroid tumors. The calcium sensing-receptor (CaSR) is expressed primarily on parathyroids, thyroid C-cells and the kidney, as well as in MTC. Further development may allow pre-operative and intra-operative detection to improve surgical outcomes.

Here at Ohio State we’re fortunate to have one of the few – and best – multidisciplinary treatment teams in the country. We care for patients while also focusing on cutting-edge research. Our team at the OSUCCC – James is a part of two large, multi-investigator NIH grants of more than $25 million dollars funding thyroid cancer research. The camaraderie and expertise among my colleagues is fantastic. There is a singular focus among us, and that’s to create a cancer-free world.

Education and Background


  • University of California San Francisco Medical Center

    San Francisco, CA


  • Washington University Hospital

    St. Louis, MO

Board Certifications

  • American Board of Surgery

Academic Department

  • Department of Surgery
  • Division of Surgical Oncology

I see patients at

The James at Martha Morehouse Outpatient Care

2050 Kenny Road, Columbus, Ohio 43221


Consulting and Related Relationships

At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 12/20/2018, Dr. Phay has reported relationships with the companies or entities listed below. If you have questions about the relationships listed below, please ask the faculty member. If you have questions about how these relationships are monitored by The Ohio State University Wexner Medical Center, please contact our Compliance Office.

  • Anasys


Clinical Trials | Lead

  • OSU-17368

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