Payal Desai, MD

The James Cancer Center
Payal Desai

A physician, or doctor, is extensively trained to diagnose and treat complex medical problems. Often, physicians focus their practice on certain disease categories, treatment methods or patient types. Physicians can diagnose and treat illness, prescribe medication, offer medical consultation and advice, perform surgery and more.


  • Hematology

Clinical Expertise

  • Hemophilia A
  • Purpura, Thrombotic Thrombocytopenic
  • von Willebrand Diseases
  • Hemophilia B
  • Benign Hematology
  • Anemia, Sickle Cell
  • Blood Coagulation
  • Thrombocytopenia
  • Thrombophilia
  • Thrombosis
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I am a hematologist and my area of expertise is treating patients with sickle cell disease, a non-cancerous blood disease that can cause a variety of very serious complications for patients. At the OSUCCC – James, I am a part of a multidisciplinary team that treats these patients and provides them with unique opportunities for clinical trials of alternative therapies to treat their disease.

I serve as director of sickle cell research for The Ohio State University and am co-director of the Sickle Cell Program. In addition, I’m involved in a variety of related national organizations, including the boards of the American Society of Hematology Sickle Cell Disease Guideline Committee and the Sickle Cell Adult Provider Network. I also serve an associate professor of internal medicine for Ohio State and have authored more than a dozen articles for publication as well as presented nearly 40 abstracts and presentations.

What I enjoy most working at The James is the tremendous desire of people to work together to provide optimal care for patients. We put aside our egos, collaborate and strive toward providing the best care and treatment for our patients in an effort to improve lives and outcomes.

Education and Background


  • University of Louisville School of Medicine

    Louisville, KY


  • University of Louisville Hospital

    Louisville, KY


  • Hematology/Oncology

    University of North Carolina Hospitals

    Chapel Hill, NC

Board Certifications

  • American Board of Internal Medicine
  • American Board of Internal Medicine (Subspecialty: Hematology)

Academic Department

I see patients at

JamesCare at Ohio State East Hospital

181 Taylor Avenue, Columbus, Ohio 43203


Consulting and Related Relationships

At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 12/20/2018, Dr. Desai has reported relationships with the companies or entities listed below. If you have questions about the relationships listed below, please ask the faculty member. If you have questions about how these relationships are monitored by The Ohio State University Wexner Medical Center, please contact our Compliance Office.

  • Ironwood Pharmaceuticals
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