Pierre Giglio, MD
Physician
Specialty:Neurooncology,Neurology
Gender: Male
Academic Title: Associate Professor in the College of Medicine
Research Program: Translational Therapeutics
About Me
More info forI am a neuro-oncologist specializing in more than 35 forms of nervous system cancers, with a research focus on glioblastoma. I also serve as an associate professor in the neurology department at the OSUCCC – James, and working alongside the talented cancer researchers and clinicians in the division of neuro-oncology is a truly rewarding experience. Additionally, I was named to the Castle Connolly list of “Regional Top Doctors” from 2015 to 2019. At The James, we are advocates for our patients and continuously seek new ways to provide the most effective treatments possible. Treating nervous system cancers requires a management approach that includes not just one physician but a team of specialists, including neurosurgeons, radiation oncologists, pathologists, neuroimaging specialists and more. Our team works with innovative technologies to perform genetic and molecular analysis of brain tumors. The combination of our expertise and technological capabilities at The James means patients receive individualized treatment plans for their specific needs. Research is also a major component of my career. As a member of the Translational Therapeutics Program at the OSUCCC – James, my research is focused on developing neuro-oncology clinical trials centering on newly diagnosed and recurrent glioblastoma, the most lethal form of brain cancer. I am particularly interested in designing clinical trials that feature targeted therapies for the treatments of patients with these tumors. I am also exploring cancer that has metastasized (spread) to the central nervous system in hopes of developing therapies based on correlative molecular studies. My work includes dozens of clinical research studies. Recently, I investigated a therapy for brain tumors utilizing components of the citrus, ginger and mushroom families that was published in the journal Tumor Biology. My work has also been published in several other top medical journals, including Anticancer Research and Neuro-Oncology. I have also presented my research to such organizations as the Brain Tumor Trials Collaborative, the International Symposium on Pediatric Neuro-Oncology and the American Society of Clinical Oncology.
Clinical Expertise
More info for- Skull Base Tumors
- Metastasis Cancers
- Brain Cancers
- Glioblastoma
- Pituitary Tumor
- Hypercholesterolemia
- Meningioma
- Brain Stem Tumor
- Hypertension
- Gliomas
- Spinal Cord Tumors
- Neurosurgery
Where I See Patients
More info forEducation & Training
More info forInternship - Internal Medicine
- University at Buffalo
Ste 7230, Buffalo, NY
Residency - Neurology
- University at Buffalo
Ste 7230, Buffalo, NY
Fellowship - Psychiatry & Neurology, Neuromuscular Medicine
- University of Chicago School of Medicine
5841 S Maryland Ave, Chicago, IL
Medical School
- University of Malta Medical School
Medical School, Block A, Level 0, Mater Dei Hospital, Guardamangia
Fellowship - Neuro-oncology
- University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd, Houston, TX
- University at Buffalo
Academic Office & Contact Information
More info forAcademic Office:
410 W 10th Ave
Columbus, Ohio 43210-1228Phone:
614-688-7592Email:
giglio.14@osu.eduReviews
More info forPatient Satisfaction Review
The overall patient satisfaction rating is an average of all patient responses to the five questions gathered from the Outpatient Oncology survey, developed by Press Ganey Associates for use in oncology clinics across the country. On behalf of The James, Press Ganey administers the survey to patients who see our providers in an outpatient clinic office. For additional information about the patient satisfaction survey, please visit our
Patient Satisfaction Survey page The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of The James.
Publications
More info forApril 1, 2024Final report of the phase II NEXT/CNS-GCT-4 trial: GemPOx followed by marrow-ablative chemotherapy for recurrent intracranial germ cell tumors.
Shatara M, Blue M, Stanek J, Liu YA, Prevedello DM, Giglio P, Puduvalli VK, Gardner SL, Allen JC, Wong KK, Nelson MD, Gilles FH, Adams RH, Pauly J, O'Halloran K, Margol AS, Dhall G, Finlay JL
Neurooncol Pract
January 1, 2024Unsupervised machine learning models reveal predictive clinical markers of glioblastoma patient survival using white blood cell counts prior to initiating chemoradiation.
Wang W, Kumm ZT, Ho C, Zanesco-Fontes I, Texiera G, Reis RM, Martinetto H, Khan J, McCandless MG, Baker KE, Anderson MD, Chohan MO, Beyer S, Elder JB, Giglio P, Otero JJ
Neurooncol Adv
December 4, 2023Glioblastoma pseudoprogression and true progression reveal spatially variable transcriptional differences.
Wang W, Tugaoen JD, Fadda P, Toland AE, Ma Q, Elder JB, Giglio P, James Cancer Center Integrated Neuro-Oncology Team , Otero JJ
Acta Neuropathol Commun
February 1, 2023Multicenter Phase II Trial of the PARP Inhibitor Olaparib in Recurrent IDH1- and IDH2-mutant Glioma.
Fanucci K, Pilat MJ, Shyr D, Shyr Y, Boerner S, Li J, Durecki D, Drappatz J, Puduvalli V, Lieberman FS, Gonzalez J, Giglio P, Ivy SP, Bindra RS, Omuro A, LoRusso P
Cancer Res Commun
November 17, 2022Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
Liau LM, Ashkan K, Brem S, Campian JL, Trusheim JE, Iwamoto FM, Tran DD, Ansstas G, Cobbs CS, Heth JA, Salacz ME, D'Andre S, Aiken RD, Moshel YA, Nam JY, Pillainayagam CP, Wagner SA, Walter KA, Chaudary R, Goldlust SA, Lee IY, Bota DA, Elinzano H, Grewal J, Lillehei K, Mikkelsen T, Walbert T, Abram S, Brenner AJ, Ewend MG, Khagi S, Lovick DS, Portnow J, Kim L, Loudon WG, Martinez NL, Thompson RC, Avigan DE, Fink KL, Geoffroy FJ, Giglio P, Gligich O, Krex D, Lindhorst SM, Lutzky J, Meisel HJ, Nadji-Ohl M, Sanchin L, Sloan A, Taylor LP, Wu JK, Dunbar EM, Etame AB, Kesari S, Mathieu D, Piccioni DE, Baskin DS, Lacroix M, May SA, New PZ, Pluard TJ, Toms SA, Tse V, Peak S, Villano JL, Battiste JD, Mulholland PJ, Pearlman ML, Petrecca K, Schulder M, Prins RM, Boynton AL, Bosch ML
JAMA Oncol
July 21, 2022Small Molecules and Immunotherapy Agents for Enhancing Radiotherapy in Glioblastoma.
Matsui JK, Perlow HK, Ritter AR, Upadhyay R, Raval RR, Thomas EM, Beyer SJ, Pillainayagam C, Goranovich J, Ong S, Giglio P, Palmer JD
Biomedicines
June 11, 2022Translational landscape of glioblastoma immunotherapy for physicians: guiding clinical practice with basic scientific evidence.
Kreatsoulas D, Bolyard C, Wu BX, Cam H, Giglio P, Li Z
J Hematol Oncol
March 31, 2022Phase I study of trametinib in combination with whole brain radiation therapy for brain metastases.
Palmer JD, Prasad RN, Fabian D, Wei L, Yildiz VO, Tan Y, Grecula J, Welliver M, Williams T, Elder JB, Raval R, Blakaj D, Haglund K, Bazan J, Kendra K, Arnett A, Beyer S, Liebner D, Giglio P, Puduvalli V, Chakravarti A, Wuthrick E
Radiother Oncol
March 28, 2022Infigratinib in Patients with Recurrent Gliomas and FGFR Alterations: A Multicenter Phase II Study.
Lassman AB, Sepúlveda-Sánchez JM, Cloughesy T, Gil-Gil MJ, Puduvalli VK, Raizer J, De Vos FYF, Wen PY, Butowski N, Clement PMJ, Groves MD, Belda-Iniesta C, Giglio P, Soifer HS, Rowsey S, Xu C, Avogadri F, Wei G, Moran S, Roth P
Clin Cancer Res
January 11, 2022Dose-escalated accelerated hypofractionation for elderly or frail patients with a newly diagnosed glioblastoma.
Perlow HK, Yaney A, Yang M, Klamer B, Matsui J, Raval RR, Blakaj DM, Arnett A, Beyer S, Elder JB, Ammirati M, Lonser R, Hardesty D, Ong S, Giglio P, Pillainayagam C, Goranovich J, Grecula J, Chakravarti A, Gondi V, Brown PD, Palmer JD
J Neurooncol
November 1, 2021Hypofractionated Dose-Escalation for Elderly Patients With a Newly Diagnosed Glioblastoma Improves Survival.
Perlow HK, Yang M, Klamer B, Raval R, Blakaj DM, Arnett ALH, Beyer S, Grecula JC, Ammirati M, Elder JB, Lonser RR, Hardesty D, Ong SS, Giglio P, Pillainayagam C, Goranovich J, Chakravarti A, Gondi V, Brown PD, Palmer JD
Int J Radiat Oncol Biol Phys
October 6, 2021Targeted Therapy for BRAF Mutant Brain Tumors.
Rayi A, Alnahhas I, Ong S, Giglio P, Puduvalli VK
Curr Treat Options Oncol
October 1, 2021Assessment of Leptomeningeal Carcinomatosis Diagnosis, Management and Outcomes in Patients with Solid Tumors Over a Decade of Experience.
Rinehardt H, Kassem M, Morgan E, Palettas M, Stephens JA, Suresh A, Ganju A, Lustberg M, Wesolowski R, Sardesai S, Stover D, Vandeusen J, Cherian M, Prieto Eibl MDPG, Miah A, Alnahhas I, Giglio P, Puduvalli VK, Ramaswamy B, Williams N, Noonan AM
Adv Psychosom Med
August 20, 2021Intraoperative 3 T MRI is more correlative to residual disease extent than early postoperative MRI.
Huntoon K, Makary MS, Damante M, Giglio P, Slone W, Elder JB
J Neurooncol
May 1, 2021Large Adult Spinal Diffuse Midline Histone H3 Lysine27-to-Methionine-Mutant Glioma With Intramedullary and Extramedullary Components Presenting With Progressive Hydrocephalus: A Case Report Highlighting Unique Imaging Findings and Treatment.
Einstein EH, Bonda D, Hosseini H, Harel A, Palmer JD, Giglio P, Barve R, Gould M, Lonser RR, D'Amico RS
Cureus
April 15, 2021Impact of cerebrospinal fluid flow study in patients undergoing intrathecal chemotherapy via ventricular catheter reservoir.
Eltobgy M, Huntoon K, Musgrave N, Shaikhouni A, Hardesty DA, Giglio P, Elder JB
J Neurooncol
February 1, 2021The role of VEGF receptor inhibitors in preventing cerebral radiation necrosis: a retrospective cohort study.
Alnahhas I, Rayi A, Palmer JD, Raval R, Folefac E, Ong S, Giglio P, Puduvalli V
Neurooncol Pract
January 1, 2021Erratum to: Characterizing Benefit from Temozolomide in MGMT Promoter Unmethylated and Methylated Glioblastoma: A Systematic Review and Meta-analysis.
Alnahhas I, Alsawas M, Rayi A, Palmer JD, Raval R, Ong S, Giglio P, Murad MH, Puduvalli V
Neurooncol Adv
January 1, 2021Prognostic implications of epidermal and platelet-derived growth factor receptor alterations in 2 cohorts of IDHwt glioblastoma.
Alnahhas I, Rayi A, Guillermo Prieto Eibl MDP, Ong S, Giglio P, Puduvalli V
Neurooncol Adv
September 1, 2020False-positive 1p/19q Testing Results in Gliomas: Clinical and Research Consequences.
Alnahhas I, Rayi A, Thomas D, Ong S, Giglio P, Puduvalli V
Am J Clin Oncol
March 13, 2020A Bayesian Adaptive Randomized Phase II Multicenter Trial of Bevacizumab with or without Vorinostat in Adults with Recurrent Glioblastoma.
Puduvalli VK, Wu J, Yuan Y, Armstrong TS, Vera E, Wu J, Xu J, Giglio P, Colman H, Walbert T, Raizer J, Groves MD, Tran D, Iwamoto F, Avgeropoulos N, Paleologos N, Fink K, Peereboom D, Chamberlain M, Merrell R, Penas Prado M, Yung WKA, Gilbert MR
Neuro Oncol
Consulting and Related Relationships
More info forAt The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 09/30/2024, Dr. Giglio has reported relationships with the companies or entities listed below. If you have questions about the relationships listed below, please ask the faculty member. If you have questions about how these relationships are monitored by The Ohio State University Wexner Medical Center, please contact our Compliance Office.
- Stocks
Patient Comments
Dr. Gilio is incredible. It doesn't get any better. It is rare to find a doctor with his mix of intelligentce and personable nature. He will make sure his patients understand what is being told to them and genuinely cares abou their well-being.
Dr Gigilio takes the time to answer all questions and has all information needed to explain.
I had a follow-up visit with Dr. Giglio, and we discussed all of my questions.
Dr. Giglio is always upbeat, thorough, and encouraging.
I am very pleased with dr. G
I give you all a raving review because your ream deserves it
Excellent care and spent time answering all my questions
Best oncologist I've ever had in 15+ years
Very impressed with care and aware this doctor has helped coordinate with information to help plan for lymphoma chemo that needed to start quickly.
Dr. Giglio gives me excellent care. I know I'm in the best medical care when I'm seen by him.
A score of five isn't good enough for Dr. Giglio. He puts me so at ease and explains everything very clearly and calmly. I can't express how much I appreciate him.
I am fairly new to this provider and have a very complicated history and my condition has very available treatment. Dr Giglio listened so carefully, gave me time to ask all my questions, and carefully thought thru his recommendations.
We trust dr Giglio
Good
Great doctor.
They are doing a good job
They were very pleased with the amount of time the oncologist gave us in the examination and also in discussing options and what enters into those options.
This was my first appointment with this specific provider. I've never been more impressed by an experience with a doctor. In my opinion it went exactly how it should have gone in a perfect world, and ours is not a perfect world. I don't expect that level to be maintained, but the fact that the doctor was able to do it once, says much about the type of doctor they are and what level of care to expect at future visits.
I was high anxiety. He was patient, positive and ensured all questions were answered but he didn't push
Dr Giglio is a very caring doctor. He makes sure I understand everything and is incredibly thorough.
Doctor took the extra time needed to explain & deserve my many issues regarding my health.
Very good.
I love my doctor, he is very thourough and informative.
Dr. Giglio cares about his patients. He is a wonderful physician.
Dr. Giglio and the nurses that saw me were all very bright and helpful. Dr. Giglio was very thorough and showed me the relevant parts of the MRI scans. He is always very patient and kind. I am glad that if I need treatment some day I will be able to have it done at OSU.
Dr. Giglio and Dr. Li are excellent care providers. They take time to explain your situation and answer questions you may have.
Excellent care from all involved.