Raju R Raval, MD, DPHIL
Academic Title: Associate Professor in the College of Medicine
Research Program: Translational Therapeutics
About Me
More info forI am a radiation oncologist who specializes in treating patients with central nervous system malignancies, including primary tumors such as glioblastoma, meningioma and ependymoma. I utilize modern treatment modalities for patients with brain and spine metastases. I completed my doctorate in molecular oncology (with graduate research in angiogenesis and tumor hypoxia) at the University of Oxford as a Rhodes Scholar, and I later received my medical degree from the University of Pennsylvania School of Medicine. As a member of the Translational Therapeutics Program at the OSUCCC – James, my laboratory focuses on translational cancer research using combinations of immunotherapy, immune modulation, targeted radiosensitization and radiation therapy. My recent research includes three clinical trials that use an immune checkpoint blockade during or after radiation for glioblastoma patients. My work has been published in more than a dozen medical journals, such as Clinical Cancer Research, Molecular Cancer Therapeutics and American Journal of Clinical Oncology. Additionally, I serve as an assistant professor of radiation oncology at The Ohio State University College of Medicine. Cancer is a terrible disease that impacts thousands of people every year. Each of us at The James is committed to working collaboratively to fight cancer and help our patients have longer, happier lives.
Clinical Expertise
More info for- Brain Cancers
- Central Nervous System Diseases
- Spinal Cord Tumors
Where I See Patients
More info forThe Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
460 W. 10th Ave. Columbus, Ohio 43210 800-293-5066 Location InformationEducation & Training
More info forInternship - Transplant Surgery
- Morristown Memorial Hospital
100 Madison Ave, Morristown, NJ
Residency - Radiation Oncology
- The Johns Hopkins Hospital
1800 Orleans St, Baltimore, MD
Medical School
- University Of Pennsylvania Health System
3400 Spruce St, Philadelphia, PA
- Morristown Memorial Hospital
Academic Office & Contact Information
More info forAcademic Office:
James Cancer Hospital A0212
460 W 10th Ave
Columbus, Ohio 43210-1240Email:
raval.18@osu.eduReviews
More info forPatient Satisfaction Review
The overall patient satisfaction rating is an average of all patient responses to the five questions gathered from the Outpatient Oncology survey, developed by Press Ganey Associates for use in oncology clinics across the country. On behalf of The James, Press Ganey administers the survey to patients who see our providers in an outpatient clinic office. For additional information about the patient satisfaction survey, please visit our
Patient Satisfaction Survey page The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of The James.
Publications
More info forOctober 4, 2024Impact of instrumentation material on local recurrence: a case-matched series using carbon fiber-PEEK vs. titanium.
Ward J, Damante M, Wilson S, Coelho V, Franceschelli D, Elguindy AN, Thomas EM, Zhu S, Blakaj D, Beyer S, Raval R, Singh R, Xu DS, Elder JB, Palmer JD, Chakravarthy VB
J Neurooncol
August 14, 2024"Intrasellar tumor-to-tumor metastasis: A single center experience with a systematic review".
Mansur G, Alsavaf MB, Pasquini L, Abouammo MD, Biswas C, Kumar P, Raval RR, Kobalka P, Carrau RL, Prevedello DM
Pituitary
July 1, 2024Safety and Feasibility of Stereotactic Radiosurgery for Patients with 15 or more Brain Metastases.
Upadhyay R, Palmer JD, Klamer BG, Perlow HK, Schoenhals JE, Ghose J, Rajappa P, Blakaj DM, Beyer S, Grecula JC, Sim AJ, Lu L, Zoller W, Elder JB, Chakravarti A, Thomas E, Raval RR
Adv Radiat Oncol
June 14, 2024NRG-BN002: Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed GBM.
Sloan AE, Winter K, Gilbert MR, Aldape K, Choi S, Wen PY, Butowski N, Iwamoto FM, Raval RR, Voloschin AD, Kamiya-Matsuoka C, Won M, Mehta MP
Neuro Oncol
May 30, 2024Disease Control and Toxicity Outcomes after Stereotactic Ablative Radiation Therapy for Recurrent and/or Metastatic Cancers in Young-Adult and Pediatric Patients.
Upadhyay R, Klamer B, Matsui J, Chakravarthy VB, Scharschmidt T, Yeager N, Setty BA, Cripe TP, Roberts RD, Aldrink JH, Singh R, Raval RR, Palmer JD, Baliga S
Cancers (Basel)
March 1, 2024Volumetric Modulated Arc Therapy Craniospinal Irradiation Utilizing a Vertebral Body Sparing Approach: An Alternative Approach to Improve Access and Minimize Toxicity.
Perlow HK, Matsui JK, Ewing A, Cadieux C, Dibs K, Upadhyay R, Blakaj DM, Beyer SJ, Thomas EM, Grecula JC, Raval RR, Palmer JD
Adv Radiat Oncol
February 1, 2024Advancing Beyond the Hippocampus to Preserve Cognition for Patients With Brain Metastases: Dosimetric Results From a Phase 2 Trial of Memory-Avoidance Whole Brain Radiation Therapy.
Perlow HK, Nalin AP, Ritter AR, Addington M, Ward A, Liu M, Nappi C, Blakaj DM, Beyer SJ, Thomas EM, Grecula JC, Raval RR, Kotecha R, Boulter D, Dawson EL, Zoller W, Palmer JD
Adv Radiat Oncol
December 27, 2023Stereotactic Radiosurgery for Women Older than 65 with Breast Cancer Brain Metastases.
Upadhyay R, Klamer BG, Perlow HK, White JR, Bazan JG, Jhawar SR, Blakaj DM, Grecula JC, Arnett A, Mestres-Villanueva MA, Healy EH, Thomas EM, Chakravarti A, Raval RR, Lustberg M, Williams NO, Palmer JD, Beyer SJ
Cancers (Basel)
October 30, 2023Vertebral Compression Fracture After Spine Stereotactic Body Radiotherapy: The Role of Vertebral Endplate Disruption.
Dibs K, Facer B, Mageswaran P, Raval R, Thomas E, Gogineni E, Beyer S, Pan J, Klamer B, Ayan A, Bourekas E, Boulter D, Fetko N, Cochran E, Zoller I, Chakravarthy V, Tili E, Elder JB, Lonser R, Elguindy A, Soghrati S, Marras W, Grecula J, Chakravarti A, Palmer J, Blakaj DM
Neurosurgery
October 27, 2023Immune checkpoint inhibition and single fraction stereotactic radiosurgery in brain metastases from non-small cell lung cancer: an international multicenter study of 395 patients.
Lehrer EJ, Khosla AA, Ozair A, Gurewitz J, Bernstein K, Kondziolka D, Niranjan A, Wei Z, Lunsford LD, Mathieu D, Trudel C, Deibert CP, Malouff TD, Ruiz-Garcia H, Peterson JL, Patel S, Bonney P, Hwang L, Yu C, Zada G, Picozzi P, Franzini A, Attuati L, Prasad RN, Raval RR, Palmer JD, Lee CC, Yang HC, Fakhoury KR, Rusthoven CG, Dickstein DR, Sheehan JP, Trifiletti DM, Ahluwalia MS
J Neurooncol
October 1, 2023Brachial Plexus Tolerance to Standard Fractionation Re-Irradiation: The Ohio State University Experience.
Dibs K, Palmer JD, Konieczkowski DJ, Gogineni E, Mitchell DL, Raval R, Baliga S, Barve R, Elguindy AN, Jhawar SR, Gamez ME, Blakaj DM
Int J Radiat Oncol Biol Phys
October 1, 2023Initial Report of Boswellia Serrata for Management of Cerebral Radiation Necrosis after Stereotactic Radiosurgery for Brain Metastases.
Upadhyay R, Elguindy AN, Sengupta S, Wang K, Beyer S, Thomas EM, Raval R, Palmer JD
Int J Radiat Oncol Biol Phys
October 1, 2023Volumetric Modulated Arc Therapy Craniospinal Irradiation Utilizing a Vertebral Body Sparing Approach: A Toxicity Analysis.
Perlow HK, Matsui JK, Ewing A, Cadieux C, Blakaj DM, Beyer S, Thomas EM, Grecula JC, Raval R, Palmer JD
Int J Radiat Oncol Biol Phys
October 1, 2023WBRT is Associated with Higher Rates of Hematologic Toxicity than Stereotactic Radiosurgery in Brain Metastasis Patients.
McCalla A, Upadhyay R, Perlow HK, Raval R, Beyer S, Blakaj DM, Grecula JC, Palmer JD, Thomas EM
Int J Radiat Oncol Biol Phys
October 1, 2023Advancing beyond the Hippocampus to Preserve Cognition for Patients with Brain Metastases: Dosimetric Results from a Phase 2 Trial of Memory-Avoidance Whole Brain Radiotherapy.
Perlow HK, Nalin A, Ritter A, Addington M, Ward A, Liu M, Nappi C, Blakaj DM, Beyer S, Thomas EM, Grecula JC, Raval R, Kotecha R, Boulter D, Dawson E, Zoller W, Palmer JD
Int J Radiat Oncol Biol Phys
October 1, 2023Patient-Reported Cognitive Outcomes and Survival after Stereotactic Radiosurgery for 15 or More Brain Metastases.
Upadhyay R, Palmer JD, Perlow HK, Schoenhals J, Ghose J, Rajappa P, Blakaj DM, Beyer S, Grecula JC, Sim AJ, Hardesty D, Elder JB, Chakravarti A, Thomas EM, Raval R
Int J Radiat Oncol Biol Phys
July 1, 2023Advances in Radiotherapy for Brain Metastases.
Matsui JK, Perlow HK, Upadhyay R, McCalla A, Raval RR, Thomas EM, Blakaj DM, Beyer SJ, Palmer JD
Surg Oncol Clin N Am
January 20, 2023Concurrent administration of immune checkpoint inhibitors and single fraction stereotactic radiosurgery in patients with non-small cell lung cancer, melanoma, and renal cell carcinoma brain metastases is not associated with an increased risk of radiation necrosis over non-concurrent treatment: An international multicenter study of 657 patients.
Lehrer EJ, Kowalchuk RO, Gurewitz J, Bernstein K, Kondziolka D, Niranjan A, Wei Z, Lunsford LD, Fakhoury KR, Rusthoven CG, Mathieu D, Trudel C, Malouff TD, Ruiz-Garcia H, Bonney P, Hwang L, Yu C, Zada G, Patel S, Deibert CP, Picozzi P, Franzini A, Attuati L, Prasad RN, Raval RR, Palmer JD, Lee CC, Yang HC, Harmsen WS, Jones BM, Sharma S, Ahluwalia MS, Sheehan JP, Trifiletti DM
Int J Radiat Oncol Biol Phys
January 1, 2023Comparing pre-operative versus post-operative single and multi-fraction stereotactic radiotherapy for patients with resectable brain metastases.
Perlow HK, Ho C, Matsui JK, Prasad RN, Klamer BG, Wang J, Damante M, Upadhyay R, Thomas E, Blakaj DM, Beyer S, Lonser R, Hardesty D, Raval RR, Prabhu R, Elder JB, Palmer JD
Clin Transl Radiat Oncol
December 5, 2022Myeloid cell heterogeneity in the tumor microenvironment and therapeutic implications for childhood central nervous system (CNS) tumors.
Kalathoor S, Rajendran S, Canella A, Raval R, Cripe TP, Mardis ER, Rajappa P
J Neuroimmunol
November 16, 2022Assessment of MRI image distortion based on 6 consecutive years of annual QAs and measurements on 14 MRI scanners used for radiation therapy.
Lu L, Yang X, Raterman B, Jiang X, Meineke M, Grecula J, Blakaj D, Palmer J, Raval R, Thomas E, Hintenlang D, Gupta N
J Appl Clin Med Phys
July 21, 2022Small Molecules and Immunotherapy Agents for Enhancing Radiotherapy in Glioblastoma.
Matsui JK, Perlow HK, Ritter AR, Upadhyay R, Raval RR, Thomas EM, Beyer SJ, Pillainayagam C, Goranovich J, Ong S, Giglio P, Palmer JD
Biomedicines
June 25, 2022Fractionated pre-operative stereotactic radiotherapy for patients with brain metastases: a multi-institutional analysis.
Palmer JD, Perlow HK, Matsui JK, Ho C, Prasad RN, Liu K, Upadhyay R, Klamer B, Wang J, Damante M, Ghose J, Blakaj DM, Beyer S, Grecula J, Arnett A, Thomas E, Chakravarti A, Lonser R, Hardesty D, Prevedello D, Prabhu R, Elder JB, Raval RR
J Neurooncol
June 1, 2022Craniospinal irradiation for respiratory failure secondary to central nervous system Erdheim-Chester disease.
Prasad RN, Kobalka PJ, Perlow HK, Prevedello DM, Blakaj DM, Raval RR, Palmer JD
Radiat Oncol J
May 2, 2022Phase 3 Trial of Chemoradiotherapy With Temozolomide Plus Nivolumab or Placebo for Newly Diagnosed Glioblastoma With Methylated MGMT Promoter.
Lim M, Weller M, Idbaih A, Steinbach J, Finocchiaro G, Raval RR, Ansstas G, Baehring J, Taylor JW, Honnorat J, Petrecca K, De Vos F, Wick A, Sumrall A, Sahebjam S, Mellinghoff IK, Kinoshita M, Roberts M, Slepetis R, Warad D, Leung D, Lee M, Reardon DA, Omuro A
Neuro Oncol
April 20, 202268Ga-DOTATATE PET-based Radiation Contouring Creates More Precise Radiation Volumes for Meningioma Patients.
Perlow HK, Siedow M, Gokun Y, McElroy J, Matsui J, Zoller W, Beyer S, Arnett A, Blakaj D, Boulter D, Fritz J, Miller E, Raval R, Kleefisch C, Bovi J, Palmer JD
Int J Radiat Oncol Biol Phys
March 31, 2022Phase I study of trametinib in combination with whole brain radiation therapy for brain metastases.
Palmer JD, Prasad RN, Fabian D, Wei L, Yildiz VO, Tan Y, Grecula J, Welliver M, Williams T, Elder JB, Raval R, Blakaj D, Haglund K, Bazan J, Kendra K, Arnett A, Beyer S, Liebner D, Giglio P, Puduvalli V, Chakravarti A, Wuthrick E
Radiother Oncol
March 22, 2022Accelerated hypofractionated radiation for elderly or frail patients with a newly diagnosed glioblastoma: A pooled analysis of patient-level data from 4 prospective trials.
Perlow HK, Prasad RN, Yang M, Klamer B, Matsui J, Marrazzo L, Detti B, Scorsetti M, Clerici E, Arnett A, Beyer S, Ammirati M, Chakravarti A, Raval RR, Brown PD, Navarria P, Scoccianti S, Grecula JC, Palmer JD
Cancer
January 11, 2022Dose-escalated accelerated hypofractionation for elderly or frail patients with a newly diagnosed glioblastoma.
Perlow HK, Yaney A, Yang M, Klamer B, Matsui J, Raval RR, Blakaj DM, Arnett A, Beyer S, Elder JB, Ammirati M, Lonser R, Hardesty D, Ong S, Giglio P, Pillainayagam C, Goranovich J, Grecula J, Chakravarti A, Gondi V, Brown PD, Palmer JD
J Neurooncol
January 1, 2022Spine Stereotactic Body Radiotherapy to Three or More Contiguous Vertebral Levels.
Dibs K, Blakaj DM, Prasad RN, Olausson A, Bourekas EC, Boulter D, Ayan AS, Cochran E, Marras WS, Mageswaran P, Thomas E, Lee H, Grecula J, Raval RR, Mendel E, Scharschmidt T, Lonser R, Chakravarti A, Elder JB, Palmer JD
Front Oncol
January 1, 2022Feasibility, safety, and efficacy of circumferential spine stereotactic body radiotherapy.
Dibs K, Palmer JD, Prasad RN, Olausson A, Bourekas EC, Boulter D, Ayan AS, Cochran E, Marras WS, Mageswaran P, Thomas E, Grecula J, Guiou M, Soghrati S, Tili E, Raval RR, Mendel E, Scharschmidt T, Elder JB, Lonser R, Chakravarti A, Blakaj DM
Front Oncol
November 1, 2021Dose-Escalated Accelerated Hypofractionation for Patients With a Newly Diagnosed Glioblastoma: A Pooled International Study.
Perlow HK, Yang M, Klamer B, Marrazzo L, Detti B, Scorsetti M, Clerici E, Arnett ALH, Beyer S, Ammirati M, Grecula JC, Chakravarti A, Raval R, Navarria P, Scoccianti S, Palmer JD
Int J Radiat Oncol Biol Phys
November 1, 2021Methylome Analysis of Rare Sinonasal Malignancies: Novel Venues for Clinical Applications.
Mladkova N, Dogan S, Yaney A, Snuderl M, Palmer JD, Gamez ME, Bonomi M, Prevedello D, Raval R, Chakravarti A, Carrau R, Blakaj DM
Int J Radiat Oncol Biol Phys
November 1, 2021Hypofractionated Dose-Escalation for Elderly Patients With a Newly Diagnosed Glioblastoma Improves Survival.
Perlow HK, Yang M, Klamer B, Raval R, Blakaj DM, Arnett ALH, Beyer S, Grecula JC, Ammirati M, Elder JB, Lonser RR, Hardesty D, Ong SS, Giglio P, Pillainayagam C, Goranovich J, Chakravarti A, Gondi V, Brown PD, Palmer JD
Int J Radiat Oncol Biol Phys
November 1, 2021Circumferential Stereotactic Body Radiotherapy for Spine Metastasis: The Feasibility, Toxicity and Local Control.
Dibs K, Palmer JD, Olausson A, Bourekas E, Boulter D, Ayan AS, Cochran ER, Yildiz V, Grecula JC, Arnett ALH, Raval R, Beyer S, Scharschmidt T, Elder JB, Chakravarti A, Mendel E, Blakaj DM
Int J Radiat Oncol Biol Phys
September 1, 2021Where Are the Women in Radiation Oncology? A Cross-Sectional Multi-Specialty Comparative Analysis.
Odei B, Kahn J, Holliday EB, Diaz DA, Bello-Pardo E, Odei J, Bae J, Arnett A, Raval R, Mitchell D
Adv Radiat Oncol
February 11, 2021Postoperative Stereotactic Body Radiotherapy for Spinal Metastasis and Predictors of Local Control.
Blakaj DM, Palmer JD, Dibs K, Olausson A, Bourekas EC, Boulter D, Ayan AS, Cochran E, Marras WS, Mageswaran P, Katzir M, Yildiz VO, Grecula J, Arnett A, Raval R, Scharschmidt T, Elder JB, Lonser R, Chakravarti A, Mendel E
Neurosurgery
February 1, 2021The role of VEGF receptor inhibitors in preventing cerebral radiation necrosis: a retrospective cohort study.
Alnahhas I, Rayi A, Palmer JD, Raval R, Folefac E, Ong S, Giglio P, Puduvalli V
Neurooncol Pract
January 1, 2021Potential Implications of the New USMLE Step 1 Pass/Fail Format for Diversity Within Radiation Oncology.
Odei B, Das P, Pinnix C, Raval R, Holliday EB
Adv Radiat Oncol
January 1, 2021Erratum to: Characterizing Benefit from Temozolomide in MGMT Promoter Unmethylated and Methylated Glioblastoma: A Systematic Review and Meta-analysis.
Alnahhas I, Alsawas M, Rayi A, Palmer JD, Raval R, Ong S, Giglio P, Murad MH, Puduvalli V
Neurooncol Adv
January 1, 2021Cerebellopontine angle ependymoma presenting as isolated hearing loss in an elderly patient: A case report and literature review.
Dibs K, Prasad RN, Madan K, Liu K, Jiang W, Ghose J, Blakaj DM, Palmer JD, Kobalka P, Prevedello DM, Raval RR
Surg Neurol Int
January 1, 2021Malignant ossifying fibromyxoid tumor of the brain treated with post-operative fractionated stereotactic radiation therapy: A case report and literature review.
Beyer S, Sebastian NT, Prasad RN, Chu J, Liu K, Madan K, Jiang W, Ghose J, Blakaj DM, Palmer JD, Eltobgy M, Otero J, Elder JB, Raval RR
Surg Neurol Int
October 1, 2020Whole-Brain Radiation Therapy Versus Stereotactic Radiosurgery for Cerebral Metastases.
Perlow HK, Dibs K, Liu K, Jiang W, Rajappa P, Blakaj DM, Palmer J, Raval RR
Neurosurg Clin N Am
August 13, 2020Recruitment Challenges and Opportunities for Radiation Oncology Residency Programs during the 2020-2021 Virtual Residency Match.
Odei B, Holliday EB, Jagsi R, Chino F, Schulmire C, Kudrimoti M, Chen A, Raval R, Fabian D
Int J Radiat Oncol Biol Phys
June 18, 2020Response to the Selective RET Inhibitor Selpercatinib (LOXO-292) in a Patient With RET Fusion-positive Atypical Lung Carcinoid.
Kander EM, Shah MH, Zhou Y, Goyal A, Palmer JD, Owen DH, Shilo K, Patel G, Raval RR, Gonzalez J, Nguyen M, Olek E, Kherani J, Rothenberg SM, Konda B
Clin Lung Cancer
June 1, 2020Clinical Outcomes and Multidisciplinary Patterns of Failure for Olfactory Neuroblastoma: The Ohio State Experience.
Wolfe AR, Blakaj D, London N, Blakaj A, Klamer B, Pan J, Wakely P, Prevedello L, Bonomi M, Bhatt A, Raval R, Palmer J, Prevedello D, Gamez M, Carrau R
J Neurol Surg B Skull Base
March 30, 2020Linear accelerator-based radiosurgery is associated with lower incidence of radionecrosis compared with gamma knife for treatment of multiple brain metastases.
Sebastian NT, Glenn C, Hughes R, Raval R, Chu J, DiCostanzo D, Bell EH, Grecula J, Arnett A, Gondal H, McGregor J, Elder JB, Lonser R, Chakravarti A, Trifiletti D, Brown PD, Chan M, Palmer JD
Radiother Oncol
Consulting and Related Relationships
More info forAt The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 09/30/2024, Dr. Raval has reported no relationships with companies or entities.
Patient Comments
Wouldn't go anywhere else
Outstanding and empathic care by Dr. Raval. Great bedside manner and explanations clear and thorough.
Dr. Rival is a very good Dr. I feel confident in him.
Super!
DR. RAVAL and staff are caring and willing to answer any questions
Dr. RAVAL and P.A. Megan make me feel like I am being taken care of very well. It is worth traveling and having my test and follow up appointment the same day. It make for a long day but very well worth it to me.
Dr. Raval is a very kind and compassionate doctor. I also value his expertise and recommendations for my daughter's care. He is one of our favorite doctors and I would highly recommend him to anyone needing a radiologist.
Kept very well informed. The medical staff had no problem answering questions.
Excellent care!
Doctor was excellent once he was in the exam room.
Great instilled confidence and showed competence well done
Dr. RAVAL is always concerned for my well being and my current health. Concerned that I am still in remission
I'm really pleased with my care team. I'd give them an A+. I deeply appreciate their scientific explanations of the brain mri etc.
Dr. Rival was thorough, compassionate, and answered all of our questions.
The most compassionate group ever!!
Good experience
Excellent.