Robert Rupert, MD

The James Cancer Center
Robert Rupert

A physician, or doctor, is extensively trained to diagnose and treat complex medical problems. Often, physicians focus their practice on certain disease categories, treatment methods or patient types. Physicians can diagnose and treat illness, prescribe medication, offer medical consultation and advice, perform surgery and more.


  • Medical Oncology
  • Hematology

Clinical Expertise

  • Laryngeal Cancers
  • Second Primary Cancers
  • Head and Neck Cancer
  • Blood Cancers
  • Hematologic Diseases
  • Skull Base Tumors
  • Hodgkin Lymphoma
  • Non-Hodgkin Lymphoma
  • Oropharyngeal Cancers
  • Mouth Cancers
  • Lung Cancers
  • Digestive System Cancers
  • Paraneoplastic Syndromes
  • Neuroendocrine Tumors
  • Unknown Primary Tumor
  • Lip Cancers
Insurance Information



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I’m a general medical oncologist with additional focus on hematology and thrombosis. I have extensive experience treating patients with solid tumors and hematologic disorders. As a member of both the Head and Neck Medical Oncology and the general hematology oncology groups at the OSUCCC – James, I’m able to apply my broad-based knowledge to treat a variety of cancer patients and hematologic issues. I feel fortunate every day to work with the brave patients and caring staff at our facilities.

I serve as medical director of oncology at JamesCare at Ohio State East Hospital and as an assistant professor in the Department of Internal Medicine. There’s a tremendous amount of camaraderie and mutual respect here, and I’m honored to be a part of this world-class organization.

At The James, we value a multidisciplinary approach to care. I enjoy collaborating with colleagues, patients, patients’ family members and outside healthcare providers to come up with individualized treatment plans. We are not reluctant to utilize innovative, cutting-edge approaches and therapies.

Finding ways to improve cancer treatment is another important part of my career. I’m a member of several clinical trial cooperative groups, including the Leukemia Group B (CALGB), the Cancer Trials Support Unit (CTSU), the National Surgical Adjuvant Breast and Bowel Project (NSABP) as well as the Radiation Therapy Oncology Group (RTOG).

Education and Background


  • Ohio State University College of Medicine

    Columbus, OH


  • Ohio State University Wexner Medical Center

    Columbus, OH


  • Hematology/Oncology

    Ohio State University Wexner Medical Center

    Columbus, OH

Board Certifications

  • American Board of Internal Medicine
  • American Board of Internal Medicine (Subspecialty: Hematology)
  • American Board of Internal Medicine (Subspecialty: Medicine Oncology)

Academic Department

I see patients at

The James Cancer Hospital and Solove Research Institute

460 West 10th Avenue, Columbus, Ohio 43210


JamesCare at Ohio State East Hospital

181 Taylor Avenue, Columbus, Ohio 43203


Consulting and Related Relationships

At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 12/20/2018, Dr. Rupert has reported no relationships with companies or entities.

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