Terence Williams, MD, PhD

The James Cancer Center
Terence Williams

A physician, or doctor, is extensively trained to diagnose and treat complex medical problems. Often, physicians focus their practice on certain disease categories, treatment methods or patient types. Physicians can diagnose and treat illness, prescribe medication, offer medical consultation and advice, perform surgery and more.


  • Radiation Oncology

Clinical Expertise

  • Esophageal Cancers
  • Gastrointestinal Cancers
  • Radiotherapy
  • Rectal Cancers
  • Stomach Cancers
  • Lip Cancers
  • Colorectal Cancers
  • Laryngeal Cancers
  • Radiotherapy, Intensity-Modulated
  • Small Cell Lung Carcinoma
  • Pancreatic Cancers
  • Liver Cancers
  • Oropharyngeal Cancers
  • Mouth Cancers
  • Lung Cancers
  • Colon Cancers
  • Carcinoid Tumor
  • Gallbladder Cancers
  • Anal Cancers
  • Anal Gland Cancer
  • Carcinoma, Non-Small-Cell Lung
Insurance Information



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I am a radiation oncologist who specializes on treating patients with thoracic and gastrointestinal cancers (with a particular emphasis on non-small cell lung cancer, pancreatic cancer, and hepatobiliary malignancies). I work with world-class colleagues in various disciplines such as surgical oncology and medical oncology to provide the best possible care for our patients.

My clinical interests include adapting novel radiotherapy techniques (such as stereotactic body radiotherapy) to improve outcomes for our patients, and utilizing functional imaging such as MRI and PET-CT to better understand how tumors respond to therapy. I am actively involved in bringing novel clinical trials to the Ohio State University, as well as developing our own clinical trials that will both provide the most innovative treatments for our patients. I serve key roles on multiple National Cancer Institute groups to develop trials incorporating new drug and radiation combinations.

Additionally, I head a research lab investigating new ways to treat cancer. My lab is funded to conduct research in DNA damage response mechanisms in normal and tumor cells after radiation or chemotherapy, particularly as it relates to oncogene activity. Oncogenes are proteins in tumor cells that are mutated and drive tumor growth and resistance to treatments. In addition, my research team and I attempt to better understand how tumors bring in nutrients into tumors cells and how these pathways may be exploited for therapeutic efficacy. Finally, we are actively involving in profiling tumors at the molecular level to identify new pathways that are aberrant and may be driving treatment resistance, as well as developing new molecular “signatures” that could predict outcomes or response to therapies.

I’ve received funding and awards from the National Cancer Institute, the National Institute of Health, the American Society of Radiation Oncology (ASTRO), American Society of Clinical Oncology (ASCO), American Cancer Society (ACS), and the Radiologic Society of North America (RSNA). I have given talks both at national and international conferences and universities regarding my research. We have also published numerous articles in medical journals including Cancer Research, Clinical Cancer Research, Journal of Clinical Oncology, Proceedings of the National Academy of Sciences, Molecular Cancer Therapeutics, and the Journal of Clinical Investigation.

Education and Background


  • Albert Einstein College of Medicine

    Bronx, NY


  • University of Michigan Medical Center

    Ann Arbor, MI

Board Certifications

  • American Board of Radiology (Subspecialty: Radiation Oncology)

Academic Department

I see patients at

The James Cancer Hospital and Solove Research Institute

460 West 10th Avenue, Columbus, Ohio 43210


Consulting and Related Relationships

At The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 12/20/2018, Dr. Williams has reported no relationships with companies or entities.


Clinical Trials | Lead

  • ALLIANCE-A021501

  • OSU-17163

  • OSU-18215

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