Claire F Verschraegen, MD
Leadership Title: Diane Nye and Michael Rayden Chair in Innovative Cancer Research
Academic Title: Professor in the College of Medicine
Research Program: Translational Therapeutics
About Me
More info forI am a professor of medicine and director of the Division of Medical Oncology at The Ohio State University College of Medicine. I also hold the Diane Nye and Michael Rayden Chair in Innovative Cancer Research at Ohio State and serve as associate director for translational research at the OSUCCC – James. I am a board-certified medical oncologist who specializes in treating patients with rare cancers, including mesothelioma, metastatic melanoma, sarcomas and gynecologic malignancies. Another of my specialties is the study of new anticancer drugs and treatments for solid tumors. My work has been continuously funded for more than 20 years, including grant support for phase I, II and III clinical trials. I have been appointed by the National Cancer Institute (NCI) to serve on many committees, such as the NCI Gynecological Cancer Steering Committee, which approves the federally-sponsored randomized studies for gynecological cancers. I was recruited to Ohio State in 2017 from the University of Vermont, where I was a professor of medicine, director of Hematology/Oncology, director of the cancer service line and co-director of the University of Vermont Cancer Center. I earned my master's degree and medical degree at the Université Libre de Bruxelles in Belgium and trained at the Institut Jules Bordet in internal medicine/oncology. I then completed a cancer research fellowship at the Stehlin Foundation for Cancer Research and an internal medicine residency training at the University of Houston followed by a medical oncology fellowship at The University of Texas MD Anderson Cancer Center. In my 30 years as an academic medical oncologist, much progress has been made in treating some cancers through novel targeted therapies and immunotherapies — a result of the well-planned clinical and translational studies to which I have devoted the greatest part of my professional life. I am privileged to continue this mission at the OSUCCC – James, with which I share a vision of creating a cancer-free world.
Clinical Expertise
More info for- Paraneoplastic Syndromes, Ocular
- Uveal Cancers
- Gynecologic Cancers
- Sarcoma
- Melanoma
- Carcinoma, Basal Cell
- Carcinoma, Merkel Cell
- Mesothelioma
- Carcinoma, Squamous Cell
Where I See Patients
More info forEducation & Training
More info forFellowship
- Christus Stehlin Foundation for Cancer Research
10301 Stella Link Rd Ste 110, Houston, TX
Medical School
- Universite Libre de Bruxelles
Campus Erasme, Route de Lennik 808 CP 610, B-1070 Brussels
Fellowship - Internal Medicine
- Universite Libre De Bruxelles Faculte De Medicine Et De Pharmacie
115 Boulevard De Waterloo, Burssels
Residency - Internal Medicine
- Universite Libre De Bruxelles Faculte De Medicine Et De Pharmacie
115 Boulevard De Waterloo, Burssels
Residency - Internal Medicine
- University of Texas Health Science Center-Houston
6410 Fannin St Ste 722, Houston, TX
Fellowship - Hematology & Oncology
- University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd, Houston, TX
- Christus Stehlin Foundation for Cancer Research
Academic Office & Contact Information
More info forAcademic Office:
Lincoln Tower 1335
1800 Cannon Dr
Columbus, Ohio 43210Email:
verschraegen.1@osu.eduReviews
More info forPatient Satisfaction Review
The overall patient satisfaction rating is an average of all patient responses to the five questions gathered from the Outpatient Oncology survey, developed by Press Ganey Associates for use in oncology clinics across the country. On behalf of The James, Press Ganey administers the survey to patients who see our providers in an outpatient clinic office. For additional information about the patient satisfaction survey, please visit our
Patient Satisfaction Survey page The comments are submitted by patients and reflect their view and opinions. The comments are not endorsed by and do not necessarily reflect the views of The James.
Videos
More info forPublications
More info forJuly 1, 2024Quality of life and patient-reported toxicities in patients with advanced Merkel cell carcinoma treated with combined nivolumab and ipilimumab with or without stereotactic body radiation therapy.
Hoogland AI, Brohl AS, Small BJ, Michael L, Wuthrick E, Eroglu Z, Blakaj D, Verschraegen C, Khushalani NI, Jim HSL, Kim S
Cancer Med
February 12, 2024Integrated multiomic profiling of breast cancer in the Chinese population reveals patient stratification and therapeutic vulnerabilities.
Jiang YZ, Ma D, Jin X, Xiao Y, Yu Y, Shi J, Zhou YF, Fu T, Lin CJ, Dai LJ, Liu CL, Zhao S, Su GH, Hou W, Liu Y, Chen Q, Yang J, Zhang N, Zhang WJ, Liu W, Ge W, Yang WT, You C, Gu Y, Kaklamani V, Bertucci F, Verschraegen C, Daemen A, Shah NM, Wang T, Guo T, Shi L, Perou CM, Zheng Y, Huang W, Shao ZM
Nat Cancer
January 12, 2024A Comprehensive Review of Immunotherapy Clinical Trials for Metastatic Urothelial Carcinoma: Immune Checkpoint Inhibitors Alone or in Combination, Novel Antibodies, Cellular Therapies, and Vaccines.
Patel DM, Mateen R, Qaddour N, Carrillo A, Verschraegen C, Yang Y, Li Z, Sundi D, Mortazavi A, Collier KA
Cancers (Basel)
January 1, 2024Hedgehog pathway inhibitors for locally advanced and metastatic basal cell carcinoma: A real-world single-center retrospective review.
Patel S, Armbruster H, Pardo G, Archambeau B, Kim NH, Jeter J, Wu R, Kendra K, Contreras CM, Spaccarelli N, Dulmage B, Pootrakul L, Carr DR, Verschraegen C
PLoS One
January 1, 2024Safety and efficacy of peptide receptor radionuclide therapy in neuroendocrine tumors: A single center experience.
Sukrithan V, Armbruster H, Rogers S, Vogt SM, Grenade C, Verschraegen C, Zhou Y, Goyal A, Natwa M, Hussein A, Barr H, Konate D, Batdorf R, Brown A, Williams B, Zhao S, Wei L, Xu M, Shah MH, Konda B
PLoS One
July 5, 2023Phase I Study of SYNB1891, an Engineered E. coli Nissle Strain Expressing STING Agonist, with and without Atezolizumab in Advanced Malignancies.
Luke JJ, Piha-Paul SA, Medina T, Verschraegen CF, Varterasian M, Brennan AM, Riese RJ, Sokolovska A, Strauss J, Hava DL, Janku F
Clin Cancer Res
May 12, 2023Phase 1 dose-escalation study evaluating the safety, pharmacokinetics, and clinical activity of OBI-3424 in patients with advanced or metastatic solid tumors.
Tsimberidou AM, Verschraegen CF, Wesolowski R, Shia CS, Hsu P, Pearce TE
Br J Cancer
May 9, 2023Phase I study of SYNB1891, an engineered E coli Nissle strain expressing STING agonist, with and without atezolizumab in advanced malignancies.
Luke JJ, Piha-Paul SA, Medina T, Verschraegen CF, Varterasian M, Brennan AM, Riese RJ, Sokolovska A, Strauss JF, Hava DL, Janku F
Clin Cancer Res
April 7, 2023Clinical markers of immunotherapy outcomes in advanced sarcoma.
Husain M, Quiroga D, Kim HG, Lenobel S, Xu M, Iwenofu H, Chen JL, Verschraegen C, Liebner D, Tinoco G
BMC Cancer
March 11, 2023Emerging Trends in Immunotherapy for Adult Sarcomas.
Husain M, Chen L, Liebner D, Beane J, Rubinstein M, Pollock R, Verschraegen C, Tinoco G
Oncologist
January 1, 2023Salvage lenvatinib/everolimus combination therapy after immune checkpoint inhibitor and VEGFR tyrosine kinase inhibitor for metastatic renal cell carcinoma.
Kwok C, Khorasanchi A, Psutka SP, Hinkley M, Dason S, Sundi D, Yang Y, Yang Y, Verschraegen C, Gross EE, Orcutt D, Yin M
Front Oncol
January 1, 2023Lung-heart toxicity in a randomized clinical trial of hypofractionated image guided radiation therapy for breast cancer.
Van Parijs H, Cecilia-Joseph E, Gorobets O, Storme G, Adriaenssens N, Heyndrickx B, Verschraegen C, Nguyen NP, De Ridder M, Vinh-Hung V
Front Oncol
September 28, 2022Candidate Bevacizumab Biosimilar CT-P16 versus European Union Reference Bevacizumab in Patients with Metastatic or Recurrent Non-Small Cell Lung Cancer: A Randomized Controlled Trial.
Verschraegen C, Andric Z, Moiseenko F, Makharadze T, Shevnya S, Oleksiienko A, Yañez Ruiz E, Kim S, Ahn K, Park T, Park S, Ju H, Ohe Y
BioDrugs
June 6, 2022Low-Dose Enzalutamide in Metastatic Prostate Cancer-Longevity Over Conventional Survival Analysis.
Vinh-Hung V, Gorobets O, Natchagande G, Sargos P, Yin M, Nguyen NP, Verschraegen C, Folefac E
Clin Genitourin Cancer
February 23, 2022Metastatic Spiradenocarcinoma Managed With PD-1 Inhibition.
Wargo JJ, Carr DR, Plaza JA, Verschraegen CF
J Natl Compr Canc Netw
February 11, 2022Long-term avelumab in advanced non-small-cell lung cancer: summaries and post hoc analyses from JAVELIN Solid Tumor.
Hrinczenko B, Iannotti N, Goel S, Spigel D, Safran H, Taylor MH, Bennouna J, Wong DJ, Kelly K, Verschraegen C, Bajars M, Manitz J, Ruisi M, Gulley JL
Future Oncol
January 24, 2022Pyrotinib plus capecitabine for patients with human epidermal growth factor receptor 2-positive breast cancer and brain metastases (PERMEATE): a multicentre, single-arm, two-cohort, phase 2 trial.
Yan M, Ouyang Q, Sun T, Niu L, Yang J, Li L, Song Y, Hao C, Chen Z, Orlandi A, Ishii N, Takabe K, Franceschini G, Ricci F, Verschraegen C, Liu Z, Zhang M, Lv H, Liu L, Yang X, Xiao H, Gao Z, Li X, Dong F, Chen X, Qiao J, Zhang G
Lancet Oncol
November 4, 2021Cardiopulmonary-related patient-reported outcomes in a randomized clinical trial of radiation therapy for breast cancer.
Van Parijs H, Vinh-Hung V, Fontaine C, Storme G, Verschraegen C, Nguyen DM, Adriaenssens N, Nguyen NP, Gorobets O, De Ridder M
BMC Cancer
August 18, 2021Phase 1 study of M2698, a p70S6K/AKT dual inhibitor, in patients with advanced cancer.
Tsimberidou AM, Shaw JV, Juric D, Verschraegen C, Weise AM, Sarantopoulos J, Lopes G, Nemunaitis J, Mita M, Park H, Ellers-Lenz B, Tian H, Xiong W, Kaleta R, Kurzrock R
J Hematol Oncol
July 14, 2021Phase II Randomized Study of CMB305 and Atezolizumab Compared With Atezolizumab Alone in Soft-Tissue Sarcomas Expressing NY-ESO-1.
Chawla SP, Van Tine BA, Pollack SM, Ganjoo KN, Elias AD, Riedel RF, Attia S, Choy E, Okuno SH, Agulnik M, von Mehren M, Livingston MB, Keedy VL, Verschraegen CF, Philip T, Bohac GC, Yurasov S, Yakovich A, Lu H, Chen M, Maki RG
J Clin Oncol
June 1, 2021Anthracycline-free or short-term regimen as adjuvant chemotherapy for operable breast cancer: A phase III randomized non-inferiority trial.
Yu KD, Liu XY, Chen L, Mo M, Wu J, Liu GY, Di GH, Verschraegen C, Stover DG, Zhuang ZG, Bertucci F, Orlandi A, Wang J, Lippi G, Wu KJ, Osman MA, Fan L, Shao ZM
Lancet Reg Health West Pac
May 18, 2021Genomic features of rapid versus late relapse in triple negative breast cancer.
Zhang Y, Asad S, Weber Z, Tallman D, Nock W, Wyse M, Bey JF, Dean KL, Adams EJ, Stockard S, Singh J, Winer EP, Lin NU, Jiang YZ, Ma D, Wang P, Shi L, Huang W, Shao ZM, Cherian M, Lustberg MB, Ramaswamy B, Sardesai S, VanDeusen J, Williams N, Wesolowski R, Obeng-Gyasi S, Sizemore GM, Sizemore ST, Verschraegen C, Stover DG
BMC Cancer
April 23, 2021Refractory dermatitis contributed by pityriasis versicolor: a case report.
Li M, Spaccarelli N, Kendra K, Wu RC, Verschraegen C
J Med Case Rep
April 20, 2021Advances in epigenetic therapeutics with focus on solid tumors.
Jin N, George TL, Otterson GA, Verschraegen C, Wen H, Carbone D, Herman J, Bertino EM, He K
Clin Epigenetics
March 10, 2021Breast cancer preoperative 18FDG-PET, overall survival prognostic separation compared with the lymph node ratio.
Vinh-Hung V, Everaert H, Gorobets O, Van Parijs H, Verfaillie G, Vanhoeij M, Storme G, Fontaine C, Lamote J, Perrin J, Farid K, Nguyen NP, Verschraegen C, De Ridder M
Breast Cancer
February 1, 2021Status of the Clinician Investigator in America: An Essential Healthcare Provider Driving Advances in Cancer Care.
Holcombe RF, Verschraegen CF, Chapman AE, Gaffney D, Goldberg RM, Mesa RA, Milhem M, Mims M, Mitchell EP, Mulkerin D, Vijayakumar S
J Natl Compr Canc Netw
November 20, 2020Increased bleeding risk associated with concurrent vascular endothelial growth factor receptor tyrosine kinase inhibitors and low-molecular-weight heparin.
Patel SH, George TL, Wang TF, Vogt SM, Folefac E, Xu M, Yang Y, Parikh AB, Verschraegen CF, Clinton SK, Yin M
Cancer
November 2, 2020Deep and Durable Response to Nivolumab and Temozolomide in Small-Cell Lung Cancer Associated With an Early Decrease in Myeloid-Derived Suppressor Cells.
Owen DH, Benner B, Pilcher C, Good L, Savardekar H, Norman R, Ghattas C, Shah M, Konda B, Verschraegen CF, Wesolowski R, Behbehani GK, Carson WE, Otterson GA
Clin Lung Cancer
September 30, 2020Benchmarks for Academic Oncology Faculty.
Anthony L, Atweh G, Bhatia R, Carey LA, Chang JC, Edelman MJ, Kantoff PW, Markham MJ, Messersmith W, Nelson EL, Oettel K, O'Regan R, Verschraegen CF, Vose JM
JCO Oncol Pract
September 1, 2020Efficacy and safety of first-line avelumab in patients with advanced non-small cell lung cancer: results from a phase Ib cohort of the JAVELIN Solid Tumor study.
Verschraegen CF, Jerusalem G, McClay EF, Iannotti N, Redfern CH, Bennouna J, Chen FL, Kelly K, Mehnert J, Morris JC, Taylor M, Spigel D, Wang D, Grote HJ, Zhou D, Munshi N, Bajars M, Gulley JL
J Immunother Cancer
July 27, 2020Molecular subtyping and genomic profiling expand precision medicine in refractory metastatic triple-negative breast cancer: the FUTURE trial.
Jiang YZ, Liu Y, Xiao Y, Hu X, Jiang L, Zuo WJ, Ma D, Ding J, Zhu X, Zou J, Verschraegen C, Stover DG, Kaklamani V, Wang ZH, Shao ZM
Cell Res
May 6, 2020Inferring the role of the microbiome on survival in patients treated with immune checkpoint inhibitors: causal modeling, timing, and classes of concomitant medications.
Spakowicz D, Hoyd R, Muniak M, Husain M, Bassett JS, Wang L, Tinoco G, Patel SH, Burkart J, Miah A, Li M, Johns A, Grogan M, Carbone DP, Verschraegen CF, Kendra KL, Otterson GA, Li L, Presley CJ, Owen DH
BMC Cancer
April 7, 2020Low-Dose Enzalutamide in Late-Elderly Patients (≥ 75 Years Old) Presenting With Metastatic Castration-Resistant Prostate Cancer.
Vinh-Hung V, Natchagande G, Joachim C, Gorobets O, Drame M, Bougas S, Folefac E, Nguyen NP, Verschraegen C, Yin M
Clin Genitourin Cancer
Consulting and Related Relationships
More info forAt The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 09/30/2024, Dr. Verschraegen has reported relationships with the companies or entities listed below. If you have questions about the relationships listed below, please ask the faculty member. If you have questions about how these relationships are monitored by The Ohio State University Wexner Medical Center, please contact our Compliance Office.
- Sun Pharma Advanced Research Company Limited
Patient Comments
Dr VERSCHAGEN. Awesome.
Dr Verschagen and her team are amazing
Best decision I every made was coming to the James.
This was an excellent experience as they always are. Dr. V. Knows my history and is always aware of my latest tests.
Great, knowledgeable, easy to understand or have explained.
Could not ask for better care! Dr. V and NP Sarah are great. True rockstars
Dr Verschraegen and her staff have always shown the utmost respect and care. They have always called me back whenever I needed guidance or help. I honestly believe they have helped lengthen my life and gave me hope for my future!
Dr. V was amazing. Very thorough, very direct and she answered all our questions. I feel very fortunate to have her as my provider.
An excellent experience.
My Dad is very satisfied and happy with his new doctor this round.
First time I felt confident in my care plan since this started
I was privileged to have creme de la creme Care. Thank You.
On a scale of 1 to 5. All 10's
Dr Vershragen provided excellent care and has excellent bedside manner - easy to communicate with
Dr Verschraegen was very patient and included us in the discussion with our mom. I was on my sisters phone by FT since I was out of state.
Dr. Old is a amazing doctor
Caring and compassion personified!!!!
Dr. Verschraegen gives me 100% attention when she is in exam room.
All treatment long, always very thorough, professional.
I have no complaints - - - only very complimentary to all staff & doctors -
Dr. and staff are excellent!
I'm treated as a person not a disease. Thank you for remembering that you treat people that have a disease process.
Excellent!