Peter G Shields, MD
Leadership Title: Julius F. Stone Chair in Cancer Research
Academic Title: Emeritus in the College of Medicine
Research Program: Cancer Control
About Me
More info forI am a medical oncologist specializing in the care of patients with lung cancer. I passionately help people achieve the best outcomes possible, and I provide my patients comprehensive, compassionate care that is tailored to their unique needs and values. As a physician-scientist and a member of the Cancer Control Program at the OSUCCC – James, I am proud to be a leader in cancer prevention research. Currently, my primary focus is on identifying biomarkers that can be used in the clinic to assess breast and lung cancer risk, particularly those related to genetics and to lifestyle factors such as diet and tobacco use. My role has also included educating and mentoring the next generation of physician-scientists. I currently hold a T32 cancer prevention training grant for postdoctoral fellows funded by the National Cancer Institute. I am an emeritus professor of both Internal Medicine at The Ohio State University College of Medicine, and of the Division of Epidemiology for the College of Public Health. My experience included more than a decade serving as the deputy director of The James, during which I was also the Julius F. Stone Chair in Cancer Research. My responsibilities included overseeing the research programs at The James through strategic planning, recruitment, funding studies and development of research infrastructure. I established university-wide collaborations that translate basic research discoveries into cancer prevention and treatment strategies. Examples include the Beating Lung Cancer in Ohio (BLCIO) and the Study of Infections and Immune REspoNse (SIIREN) studies. I have published more than 300 studies in peer-reviewed scientific journals on topics ranging from toxicology and epidemiology to behavior and health disparities. I have directed multiple large research projects, including epidemiology studies and clinical trials funded by the National Cancer Institute (NCI) and the National Institute of Drug Abuse (NIDA). I previously led a study funded by the Department of Defense Breast Cancer Center of Excellence that focused on understanding why alcohol consumption can lead to breast cancer. Other projects focused on topics including tobacco-related cancer risks, the health impacts of electronic cigarettes and health policy. I am a fellow in the American College of Epidemiology. I previously served as president of the American Society of Preventive Oncology, and I led the Molecular Epidemiology Group of the American Association for Cancer Research.
Clinical Expertise
More info for- Lung Cancers
- Carcinoma, Non-Small-Cell Lung
- Mesothelioma
Research Interests
More info for- Carcinoid Tumor
Where I See Patients
More info forEducation & Training
More info forFellowship - Hematology & Oncology
- George Washington University Medical Center
900 23Rd St Nw, Washington, DC
Internship - Internal Medicine
- George Washington University Medical Center
900 23Rd St Nw, Washington, DC
Residency - Internal Medicine
- George Washington University Medical Center
900 23Rd St Nw, Washington, DC
Medical School
- Icahn School of Medicine at Mount Sinai
1 Gustave L Levy Pl, New York, NY
- George Washington University Medical Center
Academic Office & Contact Information
More info forAcademic Office:
James Cancer Hospital
460 W 10th Ave
Columbus, Ohio 43210-1240Phone:
614-688-6563Email:
shields.167@osu.eduVideos
More info forPublications
More info forSeptember 26, 2024Lung cancer patients' illness perceptions: Prognostic for psychological and physical health trajectories.
Valentine TR, Park KR, Presley CJ, Shields PG, Andersen BL
Health Psychology
September 7, 2024Functional resilience and overall survival in adults treated for advanced non-small-cell lung cancer.
Presley CJ, Tang J, Benedict J, Grogan M, Reisinger S, Janse S, Wong ML, Arrato NA, Davenport A, Shields PG, Andersen BL
Lung Cancer
September 2, 2024Restrictions of cigarette and e-cigarette flavor and filter ventilation on demand and substitution in the Experimental Tobacco Marketplace.
Freitas-Lemos R, Tegge AN, Tomlinson DC, Athamneh LN, Stein JS, Stepanov I, Shields PG, Hatsukami DK, Bickel WK
Drug Alcohol Depend
August 3, 2024Estimating the causal effect of filter ventilation levels in cigarettes on past 30-day smoking.
Eaton AA, Hatsukami DK, Stepanov I, Shields PG, Carroll DM
Nicotine Tob Res
June 20, 2024Sex-related DNA methylation is associated with inflammation and gene expression in the lungs of healthy individuals.
Patel D, McElroy JP, Weng DY, Sahar K, Reisinger SA, Freudenheim JL, Wewers MD, Shields PG, Song MA
Sci Rep
May 31, 2024Selective Reduction of Socioeconomic Disparities in the Experimental Tobacco Marketplace: Effects of Cigarette and E-cigarette Flavor Restrictions.
Freitas-Lemos R, Tegge AN, Shevorykin A, Tomlinson DC, Athamneh LN, Stein JS, Sheffer CE, Shields PG, Hatsukami DK, Bickel WK
Nicotine Tob Res
April 5, 2024CLO24-061: Overall Survival (OS) Impact for NSCLC Patients With irAE and Non-irAE Hospital Admissions During First-Line Pembrolizumab Treatment.
Khorasanchi A, Zhao S, Wei L, Li M, Ho K, Abu-Sbeih H, Goodyear E, Secor A, Shields P, He K, Kaufman J, Memmott R, Alahmadi A, Carbone D, Otterson G, Meara A, Presley C, Owen D
J Natl Compr Canc Netw
February 20, 2024A Phase II Trial of Primary Tumor SBRT Boost Prior to Concurrent Chemoradiation for Locally-Advanced Non-Small Cell Lung Cancer.
Williams TM, Miller E, Welliver M, Brownstein J, Otterson G, Owen D, Haglund K, Shields P, Bertino E, Presley C, He K, Naduparambil J, Walston S, Pan J, Yang X, Knopp M, Essan JK, McElroy J, Mo X, McElroy S, Carbone D, Bazan J
Int J Radiat Oncol Biol Phys
January 4, 2024mRNA vaccines against SARS-CoV-2 induce divergent antigen-specific T-cell responses in patients with lung cancer.
Song NJ, Chakravarthy KB, Jeon H, Bolyard C, Reynolds K, Weller KP, Reisinger S, Wang Y, Li A, Jiang S, Ma Q, Barouch DH, Rubinstein MP, Shields PG, Oltz EM, Chung D, Li Z
J Immunother Cancer
November 1, 2023Association Between Pretreatment Chest Imaging and Immune Checkpoint Inhibitor Pneumonitis Among Patients With Lung Cancer.
Wong A, Riley M, Zhao S, Zimmer J, Viveiros M, Wang JG, Esguerra V, Li M, Lopez G, Kendra K, Carbone DP, He K, Alahmadi A, Kaufman J, Memmott RM, Shields PG, Brownstein J, Haglund K, Welliver M, Otterson GA, Presley CJ, Wei L, Owen DH, Ho K
J Natl Compr Canc Netw
October 31, 2023Illegal product purchasing in the experimental tobacco marketplace: Effects of menthol cigarette and cigarette ventilation ban.
Freitas-Lemos R, Tegge AN, Tomlinson DC, Yeh YH, Stein JS, Michael Cummings K, Fong GT, Shields PG, Hatsukami DK, Bickel WK
Drug Alcohol Depend
October 11, 2023Accelerated epigenetic age, inflammation, and gene expression in lung: comparisons of smokers and vapers with non-smokers.
Song MA, Mori KM, McElroy JP, Freudenheim JL, Weng DY, Reisinger SA, Brasky TM, Wewers MD, Shields PG
Clin Epigenetics
September 1, 2023Role of untargeted omics biomarkers of exposure and effect for tobacco research.
Shields PG
Addict Neurosci
August 18, 2023COVID-19 or Cancer Stress? Anxiety and Depressive Symptoms in Patients with Advanced Lung Cancer.
Blevins TR, Lo SB, Coker CA, Arrato NA, Reisinger SA, Shields PG, Andersen BL
Int J Behav Med
June 22, 2023Long-term impact of daily E-cigarette exposure on the lungs of asthmatic mice.
Song MA, Wold LE, Aslaner DM, Archer KJ, Patel D, Jeon H, Chung D, Shields PG, Christman JW, Chung S
Nicotine Tob Res
May 26, 2023A Pilot Cross-Sectional Study of Immunological and Microbiome Profiling Reveals Distinct Inflammatory Profiles for Smokers, Electronic Cigarette Users, and Never-Smokers.
Shields PG, Ying KL, Brasky TM, Freudenheim JL, Li Z, McElroy JP, Reisinger SA, Song MA, Weng DY, Wewers MD, Whiteman NB, Yang Y, Mathé EA
Microorganisms
March 1, 2023Smoking Cessation, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology.
Shields PG, Bierut L, Arenberg D, Balis D, Cinciripini PM, Davis J, Edmondson D, Feliciano J, Hitsman B, Hudmon KS, Jaklitsch MT, Leone FT, Ling P, McCarthy DE, Ong MK, Park ER, Prochaska J, Sandoval AJ, Sheffer CE, Spencer S, Studts JL, Tanvetyanon T, Tindle HA, Tong E, Triplette M, Urbanic J, Videtic G, Warner D, Whitlock CW, McCullough B, Darlow S
J Natl Compr Canc Netw
October 7, 2022Lung mitochondrial DNA copy number, inflammatory biomarkers, gene transcription and gene methylation in vapers and smokers.
Mori KM, McElroy JP, Weng DY, Chung S, Fadda P, Reisinger SA, Ying KL, Brasky TM, Wewers MD, Freudenheim JL, Shields PG, Song MA
EBioMedicine
July 1, 2022Association of Allostatic Load With Overall Mortality Among Patients With Metastatic Non-Small Cell Lung Cancer.
Obeng-Gyasi S, Li Y, Carson WE, Reisenger S, Presley CJ, Shields PG, Carbone DP, Ceppa DP, Carlos RC, Andersen BL
JAMA Netw Open
June 6, 2022Saliva and Lung Microbiome Associations with Electronic Cigarette Use and Smoking.
Ying KL, Brasky TM, Freudenheim JL, McElroy JP, Nickerson QA, Song MA, Weng DY, Wewers MD, Whiteman NB, Mathe EA, Shields PG
Cancer Prev Res (Phila)
June 1, 2022Illness perception profiles and psychological and physical symptoms in newly diagnosed advanced non-small cell lung cancer.
Valentine TR, Presley CJ, Carbone DP, Shields PG, Andersen BL
Health Psychology
June 1, 2022Functional Trajectories and Resilience Among Adults With Advanced Lung Cancer.
Presley CJ, Arrato NA, Shields PG, Carbone DP, Wong ML, Benedict J, Reisinger SA, Han L, Gill TM, Allore H, Andersen BL, Janse S
JTO Clin Res Rep
February 1, 2022Cancer Treatment During COVID-19: Resilience of Individuals With Advanced Non-Small Cell Lung Cancer Versus Community Controls.
Arrato NA, Lo SB, Coker CA, Covarrubias JJ, Blevins TR, Reisinger SA, Presley CJ, Shields PG, Andersen BL
J Natl Compr Canc Netw
January 8, 2022Serum Albumin: Early Prognostic Marker of Benefit for Immune Checkpoint Inhibitor Monotherapy But Not Chemoimmunotherapy.
Guo Y, Wei L, Patel SH, Lopez G, Grogan M, Li M, Haddad T, Johns A, Ganesan LP, Yang Y, Spakowicz DJ, Shields PG, He K, Bertino EM, Otterson GA, Carbone DP, Presley C, Kulp SK, Mace TA, Coss CC, Phelps MA, Owen DH
Clin Lung Cancer
December 30, 2021COVID-19 mRNA booster vaccines elicit strong protection against SARS-CoV-2 Omicron variant in patients with cancer.
Zeng C, Evans JP, Chakravarthy K, Qu P, Reisinger S, Song NJ, Rubinstein MP, Shields PG, Li Z, Liu SL
Cancer Cell
December 2, 2021Risk perceptions and continued smoking as a function of cigarette filter ventilation level among US youth and young adults who smoke.
Carroll DM, Tessier KM, Cummings KM, O'Connor RJ, Reisinger S, Shields PG, Stepanov IS, Luo X, Hatsukami DK, Rees VW
Tob Control
November 21, 2021Impaired neutralizing antibody response to COVID-19 mRNA vaccines in cancer patients.
Zeng C, Evans JP, Reisinger S, Woyach J, Liscynesky C, Boghdadly ZE, Rubinstein MP, Chakravarthy K, Saif L, Oltz EM, Gumina RJ, Shields PG, Li Z, Liu SL
Cell Biosci
November 1, 2021A Phase II Trial of Primary Tumor SBRT Boost Prior to Concurrent Chemoradiation for Locally-Advanced Non-Small Cell Lung Cancer (LA-NSCLC).
Williams TM, Welliver MX, Brownstein JM, Otterson G, Owen D, Pan J, Haglund KE, Shields PG, Bertino EM, Presley C, He K, Miller ED, Yang X, Knopp M, Essan JK, McElroy S, Carbone DP, Bazan JG
Int J Radiat Oncol Biol Phys
October 19, 2021The experimental tobacco marketplace: Effects of low-ventilated cigarette exposure.
Freitas-Lemos R, Tegge AN, Stein JS, DeHart WB, Reisinger SA, Shields PG, Hatsukami DK, Bickel WK
Addict Behav
October 9, 2021Psychological Symptom Trajectories and Non-Small Cell Lung Cancer Survival: A Joint Model Analysis.
Andersen BL, McElroy JP, Carbone DP, Presley CJ, Smith RM, Shields PG, Brock GN
Psychosomatic Medicine
May 3, 2021Functional Disability Among Older Versus Younger Adults With Advanced Non-Small-Cell Lung Cancer.
Presley CJ, Arrato NA, Janse S, Shields PG, Carbone DP, Wong ML, Han L, Gill TM, Allore HG, Andersen BL
JCO Oncol Pract
April 20, 2021Bone Metastases, Skeletal-Related Events, and Survival in Patients With Metastatic Non-Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitors.
Qin A, Zhao S, Miah A, Wei L, Patel S, Johns A, Grogan M, Bertino EM, He K, Shields PG, Kalemkerian GP, Gadgeel SM, Ramnath N, Schneider BJ, Hassan KA, Szerlip N, Chopra Z, Journey S, Waninger J, Spakowicz D, Carbone DP, Presley CJ, Otterson GA, Green MD, Owen DH
J Natl Compr Canc Netw
January 1, 2021Prospective Statewide Study of Universal Screening for Hereditary Colorectal Cancer: The Ohio Colorectal Cancer Prevention Initiative.
Pearlman R, Frankel WL, Swanson BJ, Jones D, Zhao W, Yilmaz A, Miller K, Bacher J, Bigley C, Nelsen L, Goodfellow PJ, Goldberg RM, Paskett E, Shields PG, Freudenheim JL, Stanich PP, Lattimer I, Arnold M, Prior TW, Haut M, Kalady MF, Heald B, Paquette I, Draper DJ, Brell JM, Mahesh S, Weeman K, Bastola S, Zangmeister J, Gowda A, Kencana F, Malcolm A, Liu Y, Cole S, Bane C, Li C, Rehmus E, Pritchard CC, Shirts BH, Jacobson A, Cummings SA, de la Chapelle A, Hampel H
JCO Precis Oncol
October 22, 2020Impact of cigarette filter ventilation on U.S. smokers' perceptions and biomarkers of exposure and potential harm.
Carroll DM, Stepanov I, O'Connor R, Luo X, Cummings KMM, Rees VW, Bickel WK, Berman ML, Ashley DL, Bansal-Travers M, Shields PG, Hatsukami DK
Cancer Epidemiol Biomarkers Prev
September 9, 2020Lipid laden macrophages and electronic cigarettes in healthy adults.
Shields PG, Song MA, Freudenheim JL, Brasky TM, McElroy JP, Reisinger SA, Weng DY, Ren R, Eissenberg T, Wewers MD, Shilo K
EBioMedicine
July 29, 2020Brief report: inhaled corticosteroid use and the risk of checkpoint inhibitor pneumonitis in patients with advanced cancer.
Li M, Spakowicz D, Zhao S, Patel SH, Johns A, Grogan M, Miah A, Husain M, He K, Bertino EM, Shields PG, Wei L, Carbone DP, Otterson GA, Presley CJ, Owen DH
Cancer Immunol Immunother
May 21, 2020Clinical and Molecular Correlates of Tumor Mutation Burden in Non-Small Cell Lung Cancer.
Sharpnack MF, Cho JH, Johnson TS, Otterson GA, Shields PG, Huang K, Carbone DP, He K
Lung Cancer
May 19, 2020Quantitation by liquid chromatography-nanoelectrospray ionization-high resolution tandem mass spectrometry of DNA adducts derived from methyl glyoxal and carboxyethylating agents in leukocytes of smokers and non-smokers.
Cheng G, Reisinger SA, Shields PG, Hatsukami DK, Balbo S, Hecht SS
Chem Biol Interact
May 1, 2020Adverse effects of electronic cigarettes on the disease-naive oral microbiome.
Ganesan SM, Dabdoub SM, Nagaraja HN, Scott ML, Pamulapati S, Berman ML, Shields PG, Wewers ME, Kumar PS
Sci Adv
May 1, 2020Adverse effects of electronic cigarettes on the disease-naive oral microbiome.
Ganesan SM, Dabdoub SM, Nagaraja HN, Scott ML, Pamulapati S, Berman ML, Shields PG, Wewers ME, Kumar PS
Sci Adv
April 3, 2020NIH Workshop Report: E-cigarette or Vaping Product Use Associated Lung Injury (EVALI): Developing a Research Agenda.
Crotty Alexander LE, Ware LB, Calfee CS, Callahan SJ, Eissenberg T, Farver C, Goniewicz ML, Jaspers I, Kheradmand F, King TE, Meyer NJ, Mikheev V, Shields PG, Shihadeh A, Strongin R, Tarran R
Am J Respir Crit Care Med
Consulting and Related Relationships
More info forAt The Ohio State University Wexner Medical Center, we support a faculty member’s research and consulting in collaboration with medical device, research and/or drug companies because a faculty member’s expertise can guide important advancements in the practice of medicine and improve patient care. In order to provide effective management of these relationships, the university requires annual disclosures from all faculty members with external interests related to their university responsibilities. As of 09/30/2024, Dr. Shields has reported relationships with the companies or entities listed below. If you have questions about the relationships listed below, please ask the faculty member. If you have questions about how these relationships are monitored by The Ohio State University Wexner Medical Center, please contact our Compliance Office.
- Burns White LLC
- Norfolk Southern Corp.
- Steptoe & Johnson, LLP
- Monsanto Company
- Duane Morris LLP
- Maron Marvel Bradley & Anderson LLC
- Hall Evans Law Firm
- Harris Beach Law Firm
- Milllberg Gordon LLC
- McDermott & Bonenberger PLLC
- Vorys, Sater, Seymour & Pease, LLP
- Knight Nicastro Law Firm
- Reifers Holmes Law Firm
- Bern Capelli Law firm
- Dentons
- Milton Leach Law Firm
- Mohan Law Firm
- Quinn Cova LLP