Center for Cancer Metabolism
Research Team
Learn more about the research team behind the Center for Cancer Metabolism.
Director
I am a professor in the Department of Radiation Oncology at The Ohio State University and a member of the Translational Therapeutics Program at the OSUCCC – James, where my work is focused on determining the key molecular targets in cancer metabolism and translating those findings into the clinical setting.
Cancer Metabolism Researchers
Jieli "Shirley" Li, MD, PhD
Metabolic Disorders, Endocrine Cancers, Cancer Related Metabolism
I am an assistant professor-clinical in the Department of Pathology at the Ohio State University. My clinical service and academic interests focus on implementing innovate laboratory tests for in vitro diagnosis, prognosis and treatment planning of cancer and endocrine diseases.
Xiaoguang “Margaret” Liu, PhD
Targeted anti-cancer therapies, drug delivery, and biomanufacturing
I am a professor in the Department of Chemical and Biomolecular Biological Engineering at The Ohio State University.
Maria Mihaylova, PhD
Aging and Cancer, Cancer Metabolism, Tumor Microenvironment
I am an assistant professor in the Department of Biological Chemistry and Pharmacology at The Ohio State University and a member of the Molecular Carcinogenesis and Chemoprevention Program.
Ioanna Papandreou PhD
Lipid Metabolism, Lipid Droplets, Mitochondria, Hypoxia, and Tumor Microenvironment
I am a member of the Cancer Biology Program at the OSUCCC – James, where my research focus is on identifying new metabolic targets for therapeutic development.
I am an assistant professor in the Department of Internal Medicine at Ohio State and a member of the Molecular Carcinogenesis and Chemoprevention Program at the OSUCCC – James, where my research focuses on the role of diet and lifestyle in cancer risk and survival, specifically among patients with gastrointestinal cancers.
Chenran Wang, PhD
Tumor microenvironment, brain metastasis, glial microenvironment
We are investigating the immuno-metabolism in the brain tumor microenvironment to understand the immune suppressive mechanisms through the regulation of glia (mainly astrocyte and microglia) by brain metastasis.
Immunometabolism Researchers
Stanley Huang, PhD
Translational immunometabolism, macrophages, inflammation
As an Associate Professor in the Department of Microbial Infection & Immunity (MI&I) and the Pelotonia Institute for Immuno-Oncology (PIIO), my lab focuses on immunometabolism — dissecting and targeting the unique metabolic programs of immune cells to modulate their responses, with the goal of developing effective immunotherapy strategies for cancer and inflammatory diseases.
Haitao Wen, MD, PhD
Glucose, Mitochondrial Metabolism, Programmed Cell Death, Antitumor Immunity
As a member of the Molecular Carcinogenesis and Chemoprevention Program at the OSUCCC – James, the long-term goal of my lab is to investigate the function and mechanism of glucose and mitochondrial metabolism in the antitumor immunity during colorectal cancer (CRC) development.
Metabolomics, Proteomics Expertise
Amanda Hummon, PhD
Metabolomics, Lipidomics, Mass Spectrometry, Nutritional Modifications, Colon Cancer
I am a member of the Molecular Carcinogenesis and Chemoprevention at the OSUCCC – James, where my research interests lie at the intersection of analytical chemistry and chemical biology, with a focus on cancer biology.
I am a member of the Molecular Carcinogenesis and Chemoprevention Program at the OSUCCC – James, where I focus on the development of mass spectrometry (MS)-based metabolomics and proteomics tools in support of cancer research.
Jiangjiang "Chris" Zhu, PhD
Mass Spectrometry-based Metabolomics, Gut Microbiome and Cancer, Cancer Biomarker Discovery
I am an assistant professor in the Department of Human Sciences at The Ohio State University and a member of the Molecular Carcinogenesis and Chemoprevention Program at the OSUCCC – James, where I specialize in metabolomics studies for cancer.
Cancer Biology and Other Fields
Xiaolin Cheng PhD
Computational Drug Design, Molecular Biophysics, and Molecular Dynamics Simulation
I am an Associate Professor in the department of Medicinal Chemistry and Pharmacognosy at the Ohio State University.
Zobeida Cruz-Monserrate, PhD
Exercise, Obesity, and Pancreatic Cancer
I am the director of the Molecular and Cellular Biology Program and Laboratory in the Division of Gastroenterology, Hepatology and Nutrition (GHN) at The Ohio State University, as well as a member of the Molecular Carcinogenesis and Chemoprevention Program at the OSUCCC – James.
Ramesh Ganju, PhD
Inflammation, Obesity-Associated Cancers, Immune Cell Metabolism
I am a professor and vice chair of experimental pathology in the Department of Pathology at The Ohio State University.
Naduparambil Jacob, PhD
Lung Cancer, Aging, Inflammation, Radiation Toxicity and Dietary Countermeasures
I am a member of the Translational Therapeutic Program at the OSUCCC – James and the co-holder of two U.S. patents related to miRNA biomarkers for radiation biodosimetry and for monitoring bone-marrow reconstitution.
I am a member of the Translational Therapeutics Program at the OSUCCC – James, where my research focuses primarily on drug-resistant ovarian cancer and ovarian cancer therapeutics.
Haichang Li, DVM, PhD
Drug/Chemo-resistances, Cell signaling, Protein-protein interactions
I am an assistant professor in the Department of Veterinary Biosciences at The Ohio State University and a member of the Translational Therapeutics Program at the OSUCCC – James, where my research focus is to study the mechanism of cancer progression and treatment resistance.
I am a member of the Molecular Carcinogenesis and Chemoprevention Program at the OSUCCC – James, where my research focuses on the regulation of the DNA repair pathway nucleotide excision repair and its connection to cancer therapy.
I am an associate professor in the Department of Radiation Oncology at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where my lab team studies the DNA damage response (DDR) and how it can be exploited for personalized medicine.
Lufang Zhou, PhD, MS, BS
Mitochondrial Energetics and Ion Channels, Redox Signaling, Cancer Therapy and Heart Failure
My primary research focus is to delineate the mechanistic link between mitochondrial dysfunction and pathophysiology of human diseases, and translate the findings into the development of novel mitochondrial-targeted therapies.