Who We Are
The OSUCCC – James Guo Lab is led by Principal Investigator Peixuan Guo, PhD, an internationally renowned researcher who serves as the Sylvan Frank Endowed Chair in Pharmaceutics and Drug Delivery Systems in the College of Pharmacy, the director for the Center for RNA Nanobiotechnology and Nanomedicine, and the president of the International Society of RNA Nanotechnology and Nanomedicine.
Dr. Guo proved the concept of RNA nanotechnology in 1998 (Guo P et al, Mol Cell. 1998 2:149 Inter-RNA interaction of phage phi29 pRNA to form a hexameric complex for viral DNA transportation; featured in Cell at the same time). He also constructed the first motor for viral DNA packaging, discovered the third type of biomotors using revolving mechanism without rotation, invented the method for using motor channel for the sensing of DNA, RNA and peptides for cancer diagnosis and genome sequencing, and received patents that are now licensed to the world’s largest company in high throughput DNA sequencing.
The Guo Lab comprises an internationally recognized team of researchers and scientists who focus on RNA nanotechnology, mechanism of biomotor and single-pore sensing for diagnosis of diseases and sequencing of DNA, RNA and proteins.
This diverse team of experts includes extremely talented scientists and researchers from across numerous medical and research disciplines: