Members

I am an associate professor in the Department of Radiation Oncology at The Ohio State University and the first recipient of the Block Lectureship Junior Faculty Award .

I am co-leader of the Cancer Biology Program at the OSUCCC – James, where my work focuses on the regulation of pre-mRNA splicing and how its disruption can lead to pediatric diseases such as cancer.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research is focused on molecular diagnosis of ocular melanoma, identification of novel targets for ocular melanoma therapy and hereditary predisposition to ocular melanoma.

I am an assistant professor in the Department of Cancer Biology and Genetics at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research investigates transcriptional regulation by the Mediator complex.

I am an assistant professor in the Department of Molecular Medicine and Therapeutics at The Ohio State University College of Medicine and a member of the Cancer Biology Program at the OSUCCC – James.

I am a medical oncologist who specializes in the treatment of breast cancer, one of the most common types of cancer in women in the United States.

I am an assistant professor in the Department of Cancer Biology and Genetics at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on how communication between cells regulates embryonic development and how disruptions in cell signaling contribute to human disease.

I am a professor in the Department of Biomedical Engineering at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James.

I am a member of the Cancer Biology Program at the OSUCCC – James.

I am the Director of the Comparative Pathology and Digital imaging Shared Resource (CPDISR) and an Assistant Professor - Clinical Track in the Department of Veterinary Biosciences in the OSU College of Veterinary Medicine.

I am the John W Wolfe Chair in Human Cancer Genetics and a member of the Cancer Biology Program at the OSUCCC – James, where I study the molecular changes in genes that lead to cancer.

My lab uses theoretical and computational approaches based on statistical physics to uncover basic mechanistic principles underlying our innate and adaptive immune response.

I am a member of the Cancer Biology Program at the OSUCCC – James and the co-holder of two U.S. patents related to medical research.

Many chemotherapeutic agents, including anthracyclines (e.g., doxorubicin) and tyrosine kinase inhibitors, disrupt autophagic flux by impairing lysosomal degradation and mitochondrial quality control, contributing to excessive oxidative stress and cellular apoptosis.

My research aims to understand vascular dysfunction/disease, focusing on atherosclerosis, peripheral artery disease, and the intersection of vascular biology and other diseases, particularly cancer, chemotherapy-induced cardiotoxicity, and diabetes-associated cardiovascular complications.

I am a distinguished professor of Biomedical Informatics, chief of the Division of Biostatistics and Population Health, and director of the Center for Biostatistics at the College of Medicine.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on how the centrosome organelle is assembled and how defects in this process might lead to chromosome segregation errors associated with human cancer cells.

I am an assistant professor in the Department of Microbial Infection and Immunity at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on investigating the molecular mechanisms that control interferon (IFN) synthesis and response.

I am a professor in the Department of Cancer Biology and Genetics at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where I focus my research on proteomics.

I am a professor and vice chair of experimental pathology in the Department of Pathology at The Ohio State University.

I am a member of the Cancer Biology Program at the OSUCCC – James, where I use a combination of engineering and biophysical and molecular techniques to identify how biomechanical properties of cancer cells and the tumor microenvironment (TME) influence oncogenic epithelial to mesenchymal transition (EMT).

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on understanding the epigenetic programming of T cells during infection and cancer.

As a member of the Cancer Biology Program at the OSUCCC – James, I have a long-standing interest in RNase P, an endonuclease involved in tRNA biogenesis.

I am a professor in the Department of Pediatrics at The Ohio State University and Nationwide Children’s Center for Microbial Pathogenesis, as well as a member of the Cancer Biology Program at the OSUCCC – James, where my research centers on microbial resistance to innate immunity.

I am an assistant professor in the Department of Molecular Genetics at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where I seek to develop a better understanding of the mechanisms controlling eukaryotic cell growth and proliferation.

I am a member of the Pelotonia Institute for Immuno-Oncology and the Cancer Biology Program at the OSUCCC – James, where my research focuses on investigating the mechanisms of regulation by unfolded protein response (UPR) and endoplasmic reticulum (ER) stress in the context of liver diseases, including cancer and fatty liver.

I am a professor in the Department of Molecular Genetics at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James.

I am a colorectal surgeon who specializes in the evaluation and management of patients with cancer of the colon, rectum and anus.

I am a tenured professor in the Department of Obstetrics and Gynecology at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James.

My group is focused on developing basic and translational models of pediatric sarcomas - devastating and aggressive solid tumors with limited therapeutic options.

A major component of the ongoing research in my laboratory is geared towards deciphering the crosstalk between DNA damage signaling and innate immune mechanisms.

I am an associate professor in the Department of Physics at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where my research interests lie in the area of quantitative biology, ranging from cellular mechanics to high-resolution, fluorescence live-cell microscopy.

As director of the Center for Childhood Cancer and Blood Diseases at Nationwide Children's Hospital, I lead a team of pediatric researchers who are working to better understand the development of childhood cancer and to transform diagnostic and treatment strategies.

As a member of the Cancer Biology Program at the OSUCCC – James, I focus my research on two cancer-related areas.

I am a professor in the Department of Biomedical Informatics at The Ohio State University and a member of the Molecular Biology and Cancer Genetics Program at the OSUCCC – James, where I study how diverse cells impact cancer development.

I am a professor in the Department of Materials Science and Engineering at The Ohio State University, and a member of the Cancer Biology Program at the OSUCCC – James.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research seeks to identify mechanisms that enable cancer cells to overcome cellular stresses associated with oncogenic growth.

Our lab investigates the molecular mechanisms driving breast and lung cancer, with a primary focus on microRNAs (miRNAs) and inflammatory mediators such as S100A7 and PLCG2.

I possess a broad computational biology and bioinformatics background with extensive training and expertise in multi-omics data analysis for RNA biology and epitranscriptomics.

I am an associate professor in the Department of Microbial Infection and Immunity at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on the areas of molecular and cellular immunology as they relate to the pathogenesis of human disease.

As a member of the Cancer Biology Program at the OSUCCC – James, I study the genetic, epigenetic and topological mechanisms that govern gene expression programs in normal and transformed lymphocytes.

I am an assistant professor in the Department of Cancer Biology and Genetics at The Ohio State University College of Medicine, where I study how cancer cells dysregulate cell cycle progression and DNA damage response.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research focus is on identifying new metabolic targets for therapeutic development.

I am the Louis Levy Professor for Cancer and a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on biological processes in breast cancer.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on mature T-cell leukemia chromosomal rearrangements.

I am an associate professor in the Department of Molecular Genetics at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on DNA double-strand break (DSB) repair in the S. pombe model system.

I am a urologist who specializes in treating patients with genitourinary cancers, including bladder, urethral, urothelial, testicular, penile and sarcoma of the urinary tract.

I am a professor and chair of the Department of Physics at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on the regulation of gene expression and cell differentiation by pioneer transcription factors and epigenetic factors.

Raphael Pollock, MD, PhD, is a practicing surgical oncologist and director of The Ohio State University Comprehensive Cancer Center (OSUCCC).

As a member of the Cancer Biology Program at the OSUCCC – James, I have two main research interests, both of which are driven by engineering principles for developing technological solutions for fundamental understanding, new diagnostic tools and new instrumentation for improving treatment outcomes.

I am a distinguished professor in polymer science in the Department of Food, Agricultural and Biological Engineering at the College of Food, Agirculture and Environmental Sciences at The Ohio State University.

As a member of the Cancer Biology Program at the OSUCCC – James, I focus my research on the development of microtechnology platforms for the isolation and characterization of circulating tumor biomarkers for cancer diagnostics and therapeutics.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on mathematical methods relevant to clinical treatment as well as public health.

I am an assistant professor in the Department of Pathology at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James.

Brian Searle is an Assistant Professor at the Ohio State University Medical Center in the Department of Biomedical Informatics and a member of the Pelotonia Institute for Immuno-Oncology (PIIO).

I am a member of the Molecular Biology and Cancer Genetics Program at the OSUCCC – James, where my research focuses on embryonic cancers, particularly neuroblastomas.

I am an assistant professor in the Department of Radiation Oncology at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on elucidating the mechanisms of cancer metastasis and developing therapies to improve outcomes for patients with metastatic disease, particularly metastatic breast cancer and metastatic soft tissue sarcoma (STS).

I am an associate professor in the Department of Biomedical Engineering at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James.

I am a member of the Cancer Biology Program at the OSUCCC – James, where I bring an engineering perspective to my research.

As a member of the Cancer Biology Program at the OSUCCC – James, I focus my research on epigenetic mechanisms that alter gene expression in response to changes in homeostasis.

I am an academy professor and professor emeritus in the Department of Mechanical and Aerospace Engineering at The Ohio State University, and a member of the Cancer Biology Program at the OSUCCC – James.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on mechanisms of genome maintenance.

I am a urologic oncology specialist providing medical and surgical care to patients with bladder and urothelial cancers.

I am a professor of Cancer Biology and Genetics at The Ohio State University, associate director for Cancer Research Training and Education Coordination (CRTEC), director of the Genomics Shared Resource at the OSUCCC – James, and a member of the Cancer Biology Program.

I am a professor in the Department of Cancer Biology and Genetics at The Ohio State University and co-leader of the Cancer Biology Program at the OSUCCC – James.

As a member of the Cancer Biology Program at the OSUCCC – James, the overarching goals of my laboratory are to elucidate points of fragility for glioblastoma using cell and molecular biology, as well as animal models, and to exploit these findings to develop treatment modalities and/or improve current standards of care, thereby altering the dismal prognosis associated with these tumors.

As a member of the Cancer Biology Program at the OSUCCC – James, I focus my research on basic and translational research projects that aim to understand the molecular mechanisms of colorectal cancer metastasis, recurrence, tumor dormancy and drug resistance.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on post-transcriptional gene regulation during development in the germline of the model system Drosophila melanogaster.

I am the founding executive director of the Steve and Cindy Rasmussen Institute for Genomic Medicine at Nationwide Children’s Hospital (NCH).

I'm a professor in the William G Lowrie Department of Chemical and Biomolecular Engineering and the Department of Biomedical Engineering at The Ohio State University.

I am a member of the OSUCCC – James Cancer Biology Program, where my research focuses on cellular processes related to the two defining characteristics of cancer: uncontrolled cell division and metastasis.

I am an assistant professor in the Department of Veterinary Biosciences at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC-James, where my research primarily focuses on understanding important molecular mechanisms and biology underlying breast cancer progression, metastasis, therapy resistance and recurrence, as well as identifying novel potential biomarkers and therapeutic targets for breast cancer treatment.

I am a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses on developing and implementing tools to study protein post-translational modifications.

I am a professor in the Department of Radiation Oncology at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where my team studies the DNA damage response (DDR) and how the process can be exploited for personalized medicine.

I am a professor at The Ohio State University with dual appointments in the Department of Biomedical Engineering and the Department of Surgery.

I am an associate professor in the Department of Pathology at The Ohio State University and a member of the Cancer Biology Program at the OSUCCC – James, where my research focuses primarily on HIV-persistent infections, HIV-associated malignancies and oncoviruses that cause cancers.