Translational Therapeutics
Members
Meet the leaders and members of the Translational Therapeutics Research Program at the OSUCCC – James who take basic science research from bench to bedside, turning cancer discoveries into clinical trials.
Leaders
I am a medical oncologist who specializes in creating cutting-edge treatments for patients with lung cancer.
I am a professor of Pediatrics at The Ohio State University and co-leader of the Translational Therapeutics Program at the OSUCCC – James.
I am a professor and chair of the Division of Medicinal Chemistry and Pharmacognosy at The Ohio State University College of Pharmacy.
Members
A comprehensive understanding of the tumor microenvironment will aid the development of holistic therapeutic strategies for the treatment of cancer.
I am a medical oncologist who specializes in treating thoracic malignancies, including non-small cell lung cancer, small cell lung cancer, thymoma and mesothelioma.
I am a member of the Translational Therapeutics Program at the OSUCCC – James, where my research is centered on characterizing the roles of different subsets of regulatory T (Treg) cells in the tumor microenvironment (TME) and their impact on cancer progression, as well as the fate commitment of antitumor T cells to exhaustion.
I am a radiation physicist in the Department of Radiation Oncology and a member of the Translational Therapeutics Program at the OSUCCC – James, where my research interests include medical image analysis, data analytics, normal tissue toxicity modeling and radiation dosimetry methods.
I became a cancer specialist because it’s an honor to care for and support people as they navigate what is likely the most challenging time in their life.
I am a member of the Translational Therapeutics Program at the OSUCCC – James, where my research explores the role of endogenous factors regulating tumor microenvironment, including tumor neovascularization and the development of new therapies.
I am a surgical oncologist who specializes in the treatment of melanoma and sarcoma.
As a member of the Translational Therapeutics Program at the OSUCCC – James, my research is focused on correlative analysis on clinical trial tissue and institutional cohorts, including genomic, epigenomic, transcriptomic, metabolomic and proteomic profiling, in order to detect novel tumor biomarkers that correlate with treatment efficacy and survival.
I am an assistant research professor in the College of Pharmacy at The Ohio State University and a member of the Translational Therapeutics Program at the OSUCCC – James.
I am a radiation oncologist and director of the Head and Neck Department of Radiation Oncology at The Ohio State University, where I also serve as an associate professor.
I’m a medical oncologist specializing in the treatment of head and neck cancers, including new chemo-radiation techniques, immunotherapy and management of patients with recurrent or metastatic cancers.
I am an Associate Professor (tenure track) in the Department of Veterinary Clinical Sciences, College of Veterinary Medicine.
I am a radiation oncologist who specializes in treating patients with thoracic malignancies like lung cancer, mesothelioma and thymoma/thymic carcinoma.
Professor Brüschweiler's research is highly cross-disciplinary in the area of biophysical chemistry as well as analytical chemistry.
I am a physician-scientist and medical oncologist at the OSUCCC – James, specializing in treating thoracic malignancies including non-small cell lung and small cell lung cancer, mesothelioma and thymoma.
I am a board-certified surgeon and formally trained surgical oncologist who has been engaged in the study of the immune response to cancer for the past two decades.
As a member of the Translational Therapeutics Program at the OSUCCC – James, I focus my research on how tumor cells permit selective oncolytic viral replication and how these same pathways influence the viral-induced immune-mediated response.
I am a professor and chair of the Department of Radiation Oncology at The Ohio State University College of Medicine.
I am a member of the Translational Therapeutics Program at the OSUCCC – James, where I bring a special perspective from the Chemical and Biomolecular Engineering Department in the College of Engineering.
My research is focused on the role of the gut and female reproductive tract microbiota in gynecologic cancer development, response to treatment and as a potential therapeutic target. To support this research, I have authored or co-authored more than 50 articles in such peer-reviewed scientific journals as Gynecologic Oncology, American Journal of Obstetrics and Gynecology, Obstetrics and Gynecology, Journal of Minimally Invasive Gynecologic Oncology and the International Journal of Gynecologic Cancer.
I am a professor in the Department of Pediatrics at The Ohio State University College of Medicine and a principal investigator at the Center for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children’s Hospital.
I’m a medical oncologist and researcher treating patients with sarcomas as well as poorly classified and difficult-to-treat tumors.
Our lab is developing a vaccine platform to boost host antitumor immunity.
I am a member of the Translational Therapeutics Program at the OSUCCC – James, where my research focuses on the Hippo signaling pathway and its role in neurofibromatosis type II cancers.
I am a clinical assistant professor in the Department of Pathology as well as the Department of Medicine, Division of Dermatology.
I am the interim CEO of the James Cancer Hospital and Solove Research Institute, where I also serve as chief medical officer.
I am a medical oncologist who specializes in treating urinary cancers including bladder, kidney, prostate, and testicular cancer.
I am a surgical oncologist who specializes in skin and soft tissue cancers, including melanoma, Merkel cell carcinoma, squamous cell carcinoma and basal cell carcinoma.
I am a gynecologic oncologist specializing in ovarian, uterine, endometrial, cervical and other female cancers.
I am a gynecologic oncologist who specializes in treating patients with endometrial, uterine, ovarian, vulvar, cervical and peritoneal cancers, as well as gestational trophoblastic disease.
I am a professor of Pediatrics at The Ohio State University, chief of the Division of Hematology/Oncology/BMT at Nationwide Children's Hospital, and a member of the Translational Therapeutics Program at the OSUCCC – James.
I am a surgical oncologist who specializes in treating patients with endocrine cancers and diseases, particularly those that arise in the thyroid, parathyroid and adrenal glands.
As a member of the Translational Therapeutics Program at the OSUCCC – James, I devote my research broadly to the tumor-host interaction, cancer immunology, cancer biology and the tumor microenvironment.
I’m a surgical oncologist with a specialty in diagnosing and treating patients with tumors of the pancreas, liver, bile duct and stomach.
A highly motivated and hardworking individual with a strong passion for basic cancer research involving identification of molecular signaling pathways and translational cancer research for early detection of ovarian cancer using exosome based protein biomarkers.
As a member of the Leukemia Research Program at the OSUCCC – James, I am focused on developing strategies to enhance cancer treatments with the goal of improving patient outcomes.
I am a pathologist specializing in patients with pancreatic diseases and gastrointestinal cancers and diseases.
I am a member of the Translational Therapeutics Program at the OSUCCC – James, where my research focuses on the development of next-generation, nanotechnology-driven platforms for fundamental and translational applications.
I am section chief of Breast Medical Oncology and an associate professor in the Division of Medical Oncology at the OSUCCC – James, where I specialize in breast cancer, immunotherapy, side effects from immunotherapy and rare subtypes of breast cancer like small-cell breast cancer.
I am a neuro-oncologist specializing in more than 35 forms of nervous system cancers, with a research focus on glioblastoma.
As a member of the Translational Therapeutics Program at the OSUCCC – James, I am interested in understanding and overcoming drug resistance in pancreatic cancer.
I am a board-certified radiation oncologist treating patients with radiation therapy as part of a multimodal, comprehensive treatment plan.
I am an assistant professor in the Department of Surgery - Division of Surgical Oncology at The Ohio State University and a member of the Translational Therapeutics Program at the OSUCCC – James.
As a member of the Translational Therapeutics Program at the OSUCCC – James, I conduct research focusing on the application of RNA nanotechnology for cancer therapy.
In my role as an otolaryngologist at the OSUCCC – James, I specialize in treating head and neck cancers.
I am a gastroenterologist who specializes in treating patients with pancreatic disorders.
I am a medical oncologist who specializes in treating peritoneal cancers stemming from gastrointestinal and gynecological origins, such as ovarian and colorectal cancer, and cancers of the appendix and small intestine.
I am a board-certified medical oncologist and assistant professor of medicine in the Thoracic Oncology Program at The Ohio State University.
My research primarily investigates the mechanisms that regulate the development, function, and homeostasis of innate immune cells.
I am a member of the Translational Therapeutic Program at the OSUCCC – James and the co-holder of four licensed U.S. patents related to miRNA biomarkers for radiation biodosimetry and for monitoring bone-marrow reconstitution.
As a member of the Translational Therapeutics Program at the OSUCCC – James, I am interested in clinical and translational research related to the study of breast cancer, head and neck cancer, and cutaneous malignancies.
As a dermatologist at The Ohio State University, I specialize in hospital dermatology and work with individuals who have complex medical diseases, drug and allergic reactions, and autoimmune skin diseases.
I am a medical oncologist who specializes in treating patients with lung cancer.
As a medical oncologist at the OSUCCC – James, I care for patients with solid tumors.
I am a medical oncologist specializing in thyroid, adrenocortical and neuroendocrine tumors.
The overarching goal of the Kroetz laboratory is to understand the molecular basis of interindividual variability in drug response and toxicity.
I am a urologist who has focused my entire professional career on bladder cancer, which is very prevalent but often suffers from a lack of awareness and research to support our understanding of it.
I am a member of the Translational Therapeutics Program at the OSUCCC – James and the founding director of the Pelotonia Institute for Immuno-Oncology (PIIO), which is dedicated to transforming the OSUCCC – James into a leader in basic and clinical immunology research, including prevention and survivorship.
I am a member of the Translational Therapeutics Program at the OSUCCC -James and a member of the Signature Program in Comparative and Translational Oncology at the OSU College of Veterinary Medicine.
I am a medical oncologist with a clinical specialization in bone and soft tissue sarcoma.
I am a tenured professor in the Department of Chemical and Biomolecular Engineering at The Ohio State University and a member of the Translational Therapeutics Program at the OSUCCC – James.
I am a board-certified medical physicist who specializes in image-guided radiation therapy, Gamma Knife radiosurgery, linear accelerator (linac)-based external beam radiation therapy, and low- and high-dose rate brachytherapy.
As a member of the Translational Therapeutics Program at the OSUCCC – James, my research is focused on translational tumor immunology, namely discovering new targets and pathways in the tumor microenvironment that can lead to improvements in patient responses to immune-based therapeutics.
I am a medical oncologist who specializes in treating gastrointestinal malignancies, such as esophageal cancers, colorectal cancers and hepatopancreaticobiliary tract cancers, which include cancers of the pancreas, ampulla, liver and biliary tract.
I lead a translational research program that identifies mechanisms by which lung cancer may become resistant to targeted therapies and develops strategies to overcome these mechanisms.
I am a radiation oncologist who specializes in treating patients with gastrointestinal cancers.
I am an assistant professor in the Division of Medical Oncology at the OSUCCC – James.
I am currently an associate professor in the Department of Biomedical Informatics and a member of the Center for Biostatistics at The Ohio State University.
I’m a medical oncologist and an Associate Professor in the Department of Internal Medicine.
Meisam Naeimi Kararoudi, DVM, PhD, is a research assistant professor of pediatrics at The Ohio State University College of Medicine.
I am a clinical professor in the Department of Pathology at The Ohio State University.
I am a medical oncologist who specializes in the treatment of breast cancer and gastrointestinal malignancies like esophageal, pancreatic and colorectal cancers, as well as hepatocellular carcinoma.
I am a professor in the Department of Obstetrics and Gynecology at The Ohio State University College of Medicine and the director of the Division of Gynecologic Oncology at the OSUCCC – James, where I've been a faculty member since 2005.
I am a medical oncologist who specializes in treating patients with thoracic malignancies, including lung cancer, mesothelioma and thymic cancers.
I am a member of the Translational Therapeutics Program at the OSUCCC – James, where my laboratory is focused on identifying therapeutic targets for kidney diseases, particularly acute kidney injury and renal cell carcinoma.
Through my research as a member of the Translational Therapeutics Program at the OSUCCC – James, I seek to explore transcriptomic, epigenetic, metabolomics, proteomic and genomic profiles of patient biopsies in order to identify the mechanisms of chemo and radiation resistance in treatment refractory tumors.
I am a radiation oncologist specializing in the treatment of central nervous system (CNS) malignancies, such as primary and secondary brain tumors as well as cancers of the spine.
I am a surgeon who specializes in the surgical and endoscopic treatment of general surgical conditions.
I am a radiation oncologist who specializes in treating patients with gastrointestinal cancers, including esophageal cancer, pancreatic cancer, colorectal cancer and liver cancer.
I am a principal investigator in the Steve and Cindy Rasmussen Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital (NCH) and director of The Rajappa Laboratory at IGM.
I am a member of the Translational Therapeutics Program at the OSUCCC – James, where my research focuses on histopathologic diagnosis of tumors.
I am a radiation oncologist who specializes in treating patients with central nervous system malignancies, including primary tumors such as glioblastoma, meningioma and ependymoma.
A person’s ability to communicate defines who they are — and hearing is one of the most fundamental aspects of communication.
I am a principal investigator in the Center for Childhood Cancer and Blood Diseases at Nationwide Children’s Hospital and a member of the Translational Therapeutics Program at the OSUCCC – James, where my research seeks to understand the biology that drives progression in pediatric sarcomas.
I am an otolaryngologist-head and neck surgeon focused on providing the very best care for our patients with head and neck cancers.
As director of the Division of Medical Oncology at the OSUCCC – James, I oversee and support specialized units providing care and conducting research for breast, endocrine, gastrointestinal, genitourinary, lung, skin, head and neck cancers and sarcoma.
I am a medical oncologist who specializes in treating patients with advanced prostate and colorectal cancers, including soft tissue sarcoma.
I am an associate professor in the Division of Medical Oncology at The Ohio State University and a researcher in the Pelotonia Institute for Immuno-Oncology at the OSUCCC – James, where I also serve as a member of the Translational Therapeutics Program.
I am an assistant professor in the Division of Biostatistics at The Ohio State University College of Public Health and a member of the Translational Therapeutics Program at the OSUCCC – James, where my research focuses on clinical trial design and analysis, especially precision medicine, Bayesian designs and multiple hypothesis testing.
I am an associate professor in The Ohio State University College of Veterinary Medicine and a member of the Translational Therapeutics Program at the OSUCCC – James, where I specialize in cancer surgery and clinical trial design in companion animals.
I’m an Assistant Professor at the Ohio State University Department of Neurology.
I am a research associate professor in the Division of Pharmaceutics and Pharmaceutical Chemistry at The Ohio State University College of Pharmacy and a member of the Translational Therapeutics Program at the OSUCCC – James.
I am a urologic surgeon with expertise in the management of genitourinary malignancies and a special interest in using robotic and minimally invasive surgery to treat cancers of the kidney, bladder, and prostate.
I am a heart-failure transplant cardiologist, and I believe that the gift of life is truly amazing.
I am the Lucius A Wing Chair of Cancer Research and Therapy, and a member of the Translational Therapeutics Program at the OSUCCC – James, where I seek to improve the long-term outcome of patients by modulating the therapeutic window of widely used chemotherapeutics.
I am a medical oncologist who specializes in the treatment of breast cancer.
I am a medical oncologist who specializes in the study and treatment of neuroendocrine cancer, thyroid cancer and adrenocortical cancer.
I am a medical oncologist who specializes in treating patients diagnosed with bone and soft tissue sarcomas.
I am a surgical oncologist and serve as the director of the Division of Surgical Oncology at the OSUCCC – James.
The Turro group has developed agents that can be used to deliver drugs and inhibitors to tumors, which remain "caged" or inactive until activated with red and near-infrared light.
I am the Stefanie Spielman Chair in Cancer Imaging and a member of the Translational Therapeutics Program at the OSUCCC – James, where my research focuses on the creation of new molecularly targeted pharmaceuticals visualized in vivo through diagnostic imaging technologies.
I am an otolaryngologist who specializes in treating tumors and cancers of the head and neck, with a particular focus on tumors of the skull base and sinonasal cavity.
I am a professor of medicine and director of the Division of Medical Oncology at The Ohio State University College of Medicine.
I am an assistant professor in the Department of Pathology at The Ohio State University and a member of the Translational Therapeutics Program at the OSUCCC – James, where my research focuses on stress response phenotypes that enhance tumor cell immunogenicity.
I am an assistant professor in the Division of Hematology at The Ohio State University and a member of the Translational Therapeutics Program at the OSUCCC —– James.
I am an assistant professor in the departments of Pediatrics and Biomedical Informatics at The Ohio State University.
I am a medical oncologist specializing in treating patients with breast cancer, including female and male breast cancers, ductal breast carcinomas, lobular carcinomas, medullary carcinomas and inflammatory breast cancers.
I am an assistant professor in the Department of Otolaryngology – Head and Neck Surgery at The Ohio State University and a member of the Translational Therapeutics Program at the OSUCCC – James.
I am a medical oncologist who specializes in managing the treatment of patients with breast cancer.
I am an adjunct professor in The Ohio State University College of Pharmacy, Division of Medicinal Chemistry and Pharmacognosy, and co-director of the Medicinal Chemistry Shared Resource (High-Throughput Screening Core) at the OSUCCC – James, where I also am in the Translational Therapeutics Program.
I am a professor in the College of Pharmacy at The Ohio State University and a member of the Translational Therapeutics Program at the OSUCCC – James.
I am a medical oncologist who specializes in treating genitourinary malignancies, including prostate, bladder, kidney and testicular cancer.
I bring a special perspective as an engineer in the Translational Therapeutics Program at the OSUCCC – James, where I am developing a navigation system to help surgeons visualize perioperative images and define better tumor margins in real time.
I am an assistant professor in the Division of Medical Oncology at The Ohio State University and a member of the TBD Program at the OSUCCC – James.
As a medical oncologist at the OSUCCC – James, I specialize in treating patients with reproductive and urinary system malignancies including prostate, bladder, kidney and testicular cancers.