Biomedical Informatics

Co-Directors: Dongjun Chung, PhD, and Lang Li, PhD

Technical Director of BISR: Maciej Pietrzak, PhD

The BISR supports advanced cancer research conducted by OSUCCC – James members by facilitating high-throughput, novel experiments that link multidimensional phenotypic and biomolecular data sets to address hypotheses related to cancer biology, treatment and prevention.

The BISR utilizes and coordinates various types of data-intensive techniques for comprehensive and integrative analysis of high-throughput, high-dimensional biological data. By working closely with OSUCCC – James researchers, the BISR customizes and implements various data analysis workflows to meet the unique needs of their projects, interprets and presents results together with research teams, contributes to publications and grant applications, and integrates into the research teams.

The BISR also assists researchers with the identification of relevant public domain data, other local data and commercial data sources, and implements mining and integrative analysis of these data sets, to fully reveal the potential of the locally generated data, generate new hypotheses and validate findings. In addition, the BISR provides big data management and sharing (DMS), analysis workflow development and standardization, novel bioinformatics tool development, and Cloud computing services to OSUCCC – James investigators. We regularly provide various workshops and seminars addressing bioinformatics questions and needs of OSUCCC – James researchers. The workshops contain hands-on activities to help researchers understand the process of data analysis and the interpretation of the results.

For more information, please visit go.osu.edu/bisr-bmi.

Key program objectives

The Specific Aims of BISR are to:

• Aim 1: Provide state-of-the-art bioinformatics and computational biology services.
• Aim 2: Provide big data management and sharing, and Cloud computing services.

Expertise

BISR leadership and staff provide OSUCCC – James investigators with state-of-the-art informatics tools, high-quality informatics analysis, and expert computational biology consultative services. Below is a list of key staff who are currently available for collaboration, direct appointment and billable work:

• Dongjun Chung, PhD – BISR Co-Director
• Lang Li, PhD – BISR Co-Director
• Maciej Pietrzak, PhD – BISR Technical Director
• Qin Ma, PhD – Faculty Advisor
• Anjun Ma, PhD – Faculty Advisor
• Lijun Cheng, PhD – Faculty Advisor
• Amy Hite, PhD – Faculty
• Ayse Selen Yilmaz, MS – Senior Bioinformatics Analyst
• Patrick Stevens, MS – Bioinformatics Analyst
• Garrett Kinnebrew, MD – Bioinformatics Analyst
• Shaohong Feng, MS – Bioinformatics Analyst