Translating Research Into Patient Care Excellence in Outcomes

The nationally renowned experts of the OSUCCC – James Skull Base Cancer Research Center are dedicated to developing and conducting cutting-edge research that advances innovative breakthroughs and treatments for patients with skull base tumors while also preparing today’s international scholars to join the ranks of world-class medical researchers.

These specialists, sub-specialists and super sub-specialists are leading research in high-tech, state-of-the-art laboratories not available anywhere else in central Ohio (and one of only a handful in the country) – transforming the way skull base tumors are prevented, detected, treated and, yes, cured.

Tumors are complex, and today, cancer is no longer solely defined by location or even by stage – there is no routine skull base or head and neck cancer. Each patient’s disease is different, acting and reacting differently to the bodies they are in and the treatments aimed at stopping them.

If you would like to learn more about the OSUCCC – James Skull Base Cancer Research Center, research fellowship opportunities, visiting scholar opportunities or post-doctoral opportunities, please call 614-293-7190 or email us at Becky.Al-Saleem@osumc.edu.

Mission

The OSUCCC – James Skull Base Research Center team’s mission is to work collaboratively to create and conduct impactful, groundbreaking research that leads to advanced surgical treatment and training and even more refined clinical procedures and therapies for skull base tumors.

Additionally, by recruiting the very best of visiting and international scholars, the Center’s experts can offer some of the most advanced, innovative training available anywhere on the worldwide medical stage – enabling many researchers to return to countries outside of the United States armed with the very latest skull base cancer research techniques and discoveries.

Plus, the Center’s internationally recognized principal investigators offer this world-class training in state-of-the-art laboratories not found anywhere else in central Ohio and among only a handful in the country.

Who We Are

The OSUCCC – James Skull Base Research Center team of research experts – led by internationally renowned surgeons Ricardo L. Carrau, MD (otolaryngology) and Daniel M. Prevedello, MD, (neurosurgery) – spans a broad range of disciplines: from medical oncologists, endocrinologists, surgical oncologists and radiation oncologists to molecular and biological pathologists, neuroradiologists and more – each specializing in specific areas of skull base research.

It’s that sub-specialization and singular focus that enables this team to discover, develop and deliver research outcomes that lead to the most advanced surgical treatments (including a wide range of tailored head-and-neck and neurological surgeries in which the experts utilize open, endoscopic and microscopic approaches), refined clinical procedures, and highly targeted, precision therapies for each patient – which can mean improved outcomes, faster responses, fewer side effects and more hope for skull base cancer patients everywhere.

The OSUCCC – James Skull Base Research Center is also one of a select few of its kind in the country, not only because of some of the most advanced technology and equipment found in its state-of-the-art laboratories, but also because of the Center’s collaboration among a unique, world-class group of scientists and researchers – placing the OSUCCC – James at the forefront of skull base tumor research worldwide.

Areas of expertise include:

  • Neurosurgery
  • Otolaryngology
  • Head and Neck Surgery
  • Skull Base Surgery

Each of these research areas has a specific focus, and each is led by world-renowned principal investigators, physician researchers, biologists, graduate students, postdoctoral scientists and research assistants:

For more information on the principal investigators or the researchers and scientists listed above, please click on a name.

What We Do

Working collaboratively, the OSUCCC – James Skull Base Cancer Research Center team shares knowledge, expertise and world-class skills to move research and discoveries from the bench to the bedside.

At any given time, numerous advanced skull base research projects are in progress within the Center, and all are designed and dedicated to discover, develop and deliver research outcomes leading to the most advanced surgical treatments, refined clinical procedures, and highly targeted, precision therapies for each patients with skull base tumors and other head and neck diseases.

Through integrative scientific research, case-based study and interdisciplinary collaboration within the lab as well as within the operating room, the OSUCCC – James skull base research experts evaluate current surgical approaches while brainstorming emerging surgical methodologies. In fact, these discussions are often continued from surgery into the lab where new techniques are measured, tested, refined and ultimately returned to the operating room where groundbreaking open, endoscopic and microscopic skull base procedures are used to improve outcomes for patients with skull base tumors.

International Scholars Program

By recruiting the very best of visiting and international scholars, the OSUCCC – James Skull Base Research Center’s experts can offer some of the most advanced, innovative training available anywhere on the worldwide medical stage – enabling many researchers to return to countries outside of the United States armed with the very latest skull base cancer research techniques and discoveries.

Visiting and international scholars can expect to study in a state-of-the-art anatomy laboratory, receiving extensive hands-on experience with cadaveric dissection, anatomical research, surgical-approaches description and refinement, and endoscopic endonasal approaches to the sinonasal cavity and brain.

In addition to the extensive hands-on cadaveric surgical training and collaboration, the international scholars program includes the opportunity to follow internationally renowned surgeons Ricardo L. Carrau, MD, (otolaryngology-head and neck surgery) and Daniel M. Prevedello, MD, (neurosurgery) in clinic and in the operating room. Scholars have a front-row seat during complex skull base surgeries while also observing the program leaders interacting with patients during clinic hours. In addition, the program offers intensive, ongoing case discussion through the weekly Skull Base Conference and monthly Pituitary Conference.

Visiting scholars also have the opportunity to collaborate in written manuscripts for nationally recognized research and science publications as well as for medical journals.

Clinical Research Accomplishments, Scientific Presentations and Publications

The OSUCCC – James Skull Base Research Center experts often present their findings and accomplishments to medical experts from around the world through presentations, publications, and numerous national and international meetings and conferences they attend throughout each year.

This includes giving more than 100 scientific presentations annually as well as earning coverage in medical journal publications.

Translational Research Accomplishments and Breakthroughs

The basic anatomical research and surgical techniques simulated in the cadaveric specimens in the OSUCCC – James Skull Base Cancer Research Center’s lab give our visiting and international scholars and guests a firsthand experience with procedures while also offering a greater anatomical knowledge.

This translates to even better surgical outcomes (including a greater extent of resection and neurological function preservation), improved patient satisfaction and even better control of the disease.

Additionally, the simulated surgical procedures in the cadaver can often lead to innovative new approaches to a disease as well as to improvements or refinements in an existing surgical technique. These are discussed with the Center’s experts and, when considered feasible, sometimes lead to new research involving multiple specimens in the lab – and perhaps eventually be utilized in the operating room.

If you would like to learn more about the OSUCCC – James Skull Base Cancer Research Center, research fellowship opportunities, visiting scholar opportunities or post-doctoral opportunities, please call 614-293-7190 or email us at Becky.Al-Saleem@osumc.edu.

Contact Us

Becky Al-Saleem
Office Assistant
2001 Polaris Parkway
Columbus, OH 43240


614-293-7190
Becky.Al-Saleem@osumc.edu

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Ricardo Carrau, MD

Division Leader


Ricardo Carrau

 

Dr. Carrau is a tenured professor, director of the Comprehensive Skull Base Surgery Program and co-director of ALT-VISION.

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Daniel Prevedello, MD

Division Leader


Daniel Prevedello

 

Dr. Prevedello is a professor in the Department of Neurological Surgery and the director for the Minimally Invasive Cranial Surgery Program.

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