Advising on Pharmaceutical Discovery and Development Strategy

As one of the largest and most research-intensive public universities in the nation, The Ohio State University has a breadth of resources. The Ohio State University Comprehensive Cancer Center (OSUCCC) has five highly interactive cancer research programs involving 293 scientists from 11 of the 15 colleges at Ohio State.

The Drug Development Institute (DDI) is staffed by scientists with experience in the pharmaceutical industry at all stages of the drug discovery and development process. Our team advises on how a project should be advanced from the earliest stages of discovery to clinical trial phases and beyond.

Our broad areas of expertise include:

  • Molecular Biology
  • Medicinal and Process Chemistry
  • Preclinical and Clinical Pharmacology
  • Pharmaceutical Industry Project Management
  • Interactive Network of Specialized Drug Development Resources

Directing Preclinical Drug Development Activities

The DDI leverages world-class research and drug development resources at The Ohio State University to advance projects from early drug discovery through preclinical and clinical development. We coordinate and manages all of the necessary early-stage drug development activities to ensure a seamless integration of project teams and timely progression of projects When appropriate, we partner with external contract research organizations to help obtain critical data.

Managing Intellectual Property

Intellectual property is the tangible, marketable core of every DDI-invested project. Each project has an intellectual property strategy defined before DDI investment. The intellectual property strategy is used to guide the drug development strategy and influences overall pipeline decisions as well. The DDI works closely with licensing officers at the Ohio State Technology Commercialization Office (TCO) to ensure that our invested projects are appropriately disclosed, patented and protected. The DDI and TCO also work together on external partnering, licensing negotiations and contract terms for invested projects.

Developing a Commercialization Strategy

The DDI evaluates the commercial viability of every technology prior to investment and regularly throughout the development process. We recognize that the pharmaceutical competitive landscape is constantly evolving and that the clinical need for a product may change dramatically within a short time. To understand and respond to changes in commercial potential, the DDI leverages both internal and external resources:

  • The DDI works with the Ohio State Fisher College of Business Center for Innovation Strategies (CIS) to analyze the commercial potential and market position for every invested drug development project. The CIS is experienced in triaging early-stage technologies and developing commercialization strategies.

  • The DDI has an advisory board consisting of highly experienced pharmaceutical industry professionals. The board advises on commercial viability and taps into its extensive networks of contacts to provide expert advice when needed.

Partnering and Managing Relationships

The DDI cultivates relationships between internal and external partners, manages alliances and is flexible with the kinds of partnerships and investment models that are developed. Pipeline projects are available for partnering at all stages in the research and development process. The DDI pipeline provides potential partners with innovative de-risked drug candidates with industry-standard data packages and consolidated intellectual property.

Leveraging Resources

The DDI leverages internal and external resources to accelerate projects. Resources include:

  • World-renowned researchers working at one of the largest public universities in the nation
  • Partnerships with OSUCCC Shared Resources that provide an integrated network of specialized and cost-effective services to facilitate innovative translational science as well as access to state-of-the-art technology and instrumentation
  • Other core resources such as assay development, compound profiling and more
  • Business analysts at the CIS
  • Licensing expertise at the TCO
  • Strategic partnerships with recognized experts in the Pharma and compound development industries as well as the government
  • Contracted capabilities such as toxicity studies
  • Partnership and collaboration with Ohio State's Pelotonia Institute for Immuno-Oncology (PIIO)

For more information, contact the DDI at

Contact the DDI

Phone: 614-685-6957 

Meet Us

The DDI Team will be at the following conference.

AACR Annual Meeting

Atlanta, Ga.
March 30-April 3, 2019

Schedule a Meeting

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