Why Partner With the DDI?
The Drug Development Institute (DDI) can accelerate your research project into new therapies for patients by:
- Providing financial resources and strategic advisory capabilities
- Identifying a pathway for clinical development and commercialization
- Providing a systematic approach to managing the drug development process through timeline and milestone management, which keeps projects on track and moving forward
- Identifying internal and external resources and collaborators to advance projects
- Potentially securing a strategic partner for further preclinical and clinical development
- Helping researchers navigate the complex pharmaceutical drug development process and culture
The final goal is to create a unique, high-value, commercially-viable therapy that addresses an unmet medical need for patients.
Pilot Funding Opportunities
As part of our routine evaluation of new projects or efforts to add value to existing projects in our pipeline, the DDI offers pilot funding opportunities to researchers whose work qualifies for pilot funding to complete additional preclinical studies. Please email us at firstname.lastname@example.org for information.
How to Partner With the DDI
Seek advice on developing a new therapy:
If you need advice on how to develop a new therapy or how to attract an industry partner, contact us to schedule a meeting during our monthly consultation hours.
DDI consulting hours occur the fourth Wednesday of every month from 10 a.m.-Noon at 480 BRT. Please email email@example.com to schedule a 30-minute consultation.
Apply for project support:
The DDI is always eager to learn more about innovative new research projects that address unmet medical needs. While we have periodic requests for new proposals, you can discuss your projects with us at our monthly consulting hours. Please email firstname.lastname@example.org to schedule a 30-minute consultation.
What Makes a Good Drug Development Project?
From a drug development perspective, a project’s probability of success depends on several factors. Criteria for a good drug development project include but are not limited to:
- Unmet medical need
- Size of patient population, availability of treatment options, major therapeutic advantage over existing therapies, disease area with high level of morbidity and mortality
- Intellectual property
- Potential to create core intellectual property, plus the ability to expand coverage over time
- Commercial viability of target indication
- Scientific rationale such as:
- Validated target (loss and/or gain of function data)
- New mechanism of action for either established or novel target
- Availability of candidate agonists or antagonists
- Potency (Kd, Ki, IC50)
- Selectivity of agonists or antagonists – on-target vs. off-target effects
- Benchmark molecule(s) – positive and negative controls
- Robust enzymatic/biochemical assay(s)
- Cellular assay(s) with assessment of downstream effects (pharmacodynamic markers)
- Animal efficacy model with pharmacodynamic readout
For more information about ways to advance your drug development project, contact the DDI at email@example.com.