Amanda Hummon, PhD
College of Arts and Sciences
Chemistry and Biochemistry
Molecular Carcinogenesis and Chemoprevention
Dr. Hummon's research interests lie at the intersection of analytical chemistry and chemical biology, with a focus on cancer biology. Her lab develops analytical methods to evaluate the proteome, phosphoproteome and metabolome in cancer cells, while exploring the deregulation in cancer-associated signal transduction pathways. They use global mass spectrometric profiling to quantitatively assess the altered abundance of biomolecules in cancer cells, particularly in colon cancer. They have used this approach to examine patient samples, mouse xenografts and immortalized cell lines. Dr. Hummon's lab also develops imaging mass spectrometry methods to track the penetration and metabolism of chemotherapies in tumors and three-dimensional cell cultures.