Anjali Mishra, PhD
College of Medicine
Res Asst Professor
Molecular Carcinogenesis and Chemoprevention
Lymphoma, T-Cell, Cutaneous, Leukemia, Myeloid, Acute, Sezary Syndrome, Cancer, Leukemia, Mycosis Fungoides, Multiple Myeloma, Lymphoma, Listeriosis, Trisomy
Dr. Mishra's research has shown stage-related ‘interleukin-15 (IL-15)’ mRNA and protein over-expression in lesional skin and circulating tumor cells of CTCL patients. Using IL-15 transgenic (tg) mice, Dr. Mishra's lab has characterized an animal model of spontaneous epidermotropic T-cell lymphoma that clinically and pathologically mimics human CTCL. The research efforts of her laboratory are focused on understanding the mechanisms of lymphomagenesis and designing therapeutic strategies for CTCL, by characterizing and targeting deregulated oncogenic pathways in IL-15 tg mice and in CTCL patients.